... and hypertension) is present in cells from non-insulin-dependent diabetes patients with microalbuminuria, a known risk factor for cardiovascular and renal disease, is unknown. We therefore examined intracellular pH and calcium changes after acute exposure to insulin and angiotensin II in cultured skin fibroblasts...

...Keith N. Frayn; Christine M. Williams; Peter Arner coronary heart disease insulin resistance non-esterified fatty acids non-insulin-dependent diabetes obesity stress Clinical Science (1996) W, 243-253 (Printed in Great Britain) Editorial Review 243 Are increased plasma non-esterified...

... and alkaline phosphatase) that originate in renal proximal tubular cells. 2. Studies were performed on 118 non-insulin-dependent diabetic patients, 59 non-diabetic patients with chronic renal disease and 47 normal control subjects. First, the correlation between renal function, glycaemic control and urinary...

..., plasma atrial natriuretic peptide and urinary dopamine, in 165 Chinese patients with non-insulin-dependent diabetes mellitus controlled by diet or oral hypoglycaemic agents on two occasions over a 6-week period. Patients were divided into three groups based on the mean value of two 24 h urinary albumin...

...% of all insulin-dependent and non-insulin-dependent diabetic patients suffer from diabetic nephropathy, which is a clinical syndrome characterized by persistent albumin- uria, a progressive decline in glomerular filtration rate (GFR) and high blood pressure [ 1,3]. Both a reduction in protein intake...

..., a group at risk of future non-insulin-dependent diabetes, have abnormalities of insulin release at a time when insulin sensitivity and fasting glucose production are normal. 18 2 1991 27 2 1991 © 1991 The Biochemical Society and the Medical Research Society 1991 gestational diabetes...

... DNA insertion at this locus were found to have a higher risk of concurrence of non-insulin-dependent diabetes (NIDD) than controls ( P < 0.01). 3. Analysis of a single large NIDD pedigree ( n = 67 in four generations; 11 diabetic subjects) showed no linkage between the size of DNA inserts...