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Keywords: non-steroidal anti-inflammatory drugs
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Articles
Effects of indomethacin on energy metabolism in rat jejunal tissue in vivo
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (2002) 102 (5): 541–546.
Published: 18 April 2002
...Molly JACOB; Ingvar BJARNASON; Robert J. SIMPSON The non-steroidal anti-inflammatory drugs (NSAIDs) are a widely used group of drugs in clinical medicine. However, their propensity to cause gastrointestinal damage limits their clinical utility. The pathogenesis of this toxicity is not well...
Articles
Effects of indomethacin on energy metabolism in rat and human jejunal tissue in vitro
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (2001) 101 (5): 493–498.
Published: 25 September 2001
...Molly JACOB; Ingvar BJARNASON; Robert J. SIMPSON Non-steroidal anti-inflammatory drugs (NSAIDs) are known to cause enteropathy, but the mechanism by which this toxicity occurs is less well established. This paper sets out to test the hypothesis that these drugs affect oxidative phosphorylation...
Articles
Non-steroidal anti-inflammatory drugs and renal response to exercise: a comparison of indomethacin and nabumetone
Available to PurchaseNiels Vidiendal OLSEN, Niels Georg JENSEN, Jesper Melchior HANSEN, Niels Juel CHRISTENSEN, Niels FOGH-ANDERSEN, Inge-Lis KANSTRUP
Journal:
Clinical Science
Clin Sci (Lond) (1999) 97 (4): 457–465.
Published: 24 August 1999
...Niels Vidiendal OLSEN; Niels Georg JENSEN; Jesper Melchior HANSEN; Niels Juel CHRISTENSEN; Niels FOGH-ANDERSEN; Inge-Lis KANSTRUP Nabumetone, a newer non-steroidal anti-inflammatory drug (NSAID) which preferentially blocks cyclo-oxygenase-2 activity, may be less nephrotoxic than indomethacin...
Articles
Assessment of Gentamicin—Induced Nephrotoxicity in Rats Treated with Low Doses of Ibuprofen and Diclofenac Sodium
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1996) 91 (2): 187–191.
Published: 01 August 1996
...M. M. Farag; M. Mikhail; R. Shehata; E. Abdel-Meguid; S. Abdel-Tawab 1. The effects of two non-steroidal anti-inflammatory drugs, ibuprofen (20 mg day −1 kg −1 ) and diclofenac sodium (2.5 mg day −1 kg −1 ), on the severity of gentamicin-induced nephrotoxicity were evaluated in rats. 2...
Articles
Additive antiproteinuric effect of angiotensin-converting enzyme inhibition and non-steroidal anti-inflammatory drug therapy: A clue to the mechanism of action
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1991) 81 (3): 367–372.
Published: 01 September 1991
...Jan E. Heeg; Paul E. de Jong; Dick de Zeeuw 1. Both the angiotensin-converting enzyme inhibitor, lisinopril, and the non-steroidal anti-inflammatory drug, indomethacin, lower urinary protein excretion in renal disease and improve the selectivity of the residual proteinuria. Despite the clearly...