.... A frequency related vasoconstriction as well as [ 3 H]noradrenaline release were observed over the stimulating range of 0.25-32 Hz in both the Wistar-Kyoto and spontaneously hypertensive rats. The spontaneously hypertensive rat kidneys exhibited both an increased vasoconstrictor response and a greater [ 3 H...

... hypertension. pump was used, and changes in renal vascular resistance were recorded as increases in perfusion Key words: noradrenaline release, renal nerves, pressure (Collis & Vanhoutte, 1977). The renal renal perfusion, spontaneous hypertensive. nerves were stimulated by peri-arterial electrodes (6 or 16 Hz...

...J. P. Chalmers 1. Presynaptic regulation. The regulation of noradrenaline release by a wide variety of substances acting on presynaptic receptors suggests that local factors may play a greater role in the control of blood pressure than was previously believed and that a number of new approaches...