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1-5 of 5
Keywords: notch signalling pathway
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (2023) 137 (15): 1145–1150.
Published: 09 August 2023
... 05 07 2023 07 07 2023 © 2023 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2023 notch signalling pathway Polycystic kidney disease renin-angiotensin system Autosomal-dominant polycystic kidney disease (ADPKD) is a form of PKD, which...
Articles
Brian C. Belyea, Fang Xu, Margaret Wiltsie, Hayes Fountain, Jennifer Charlton, Agnes B. Fogo, Maria Luisa Soledad Sequeira-Lopez, Roberto Ariel Gomez
Journal:
Clinical Science
Clin Sci (Lond) (2023) 137 (1): 35–45.
Published: 05 January 2023
... developed in both glomeruli and proximal tubules, had increased proliferation marks, and had increased levels of Myc. The present work implicates the Notch signaling pathway as a central player in PKD pathogenesis and suggests that the Notch-Myc axis may be an important target for therapeutic intervention...
Includes: Supplementary data
Articles
Ning Hu, Xiaoyi Zhang, Xuanzhe Zhang, Yongjun Guan, Ruyuan He, Enfu Xue, Xiaoyi Zhang, Wenhong Deng, Jia Yu, Weixing Wang, Qiao Shi
Journal:
Clinical Science
Clin Sci (Lond) (2022) 136 (7): 455–471.
Published: 06 April 2022
... the production of proinflammatory factors, thus mitigating pancreatic injury. These findings suggest that hyperglycemia induces excessive Notch signaling after AP and further aggravates AP by promoting pancreatic macrophage polarization towards the M1 phenotype. The Notch signaling pathway is a potential target...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (10): 1209–1212.
Published: 20 May 2021
.... Correspondence: Anton J.M. Roks ( [email protected] ) 19 04 2021 06 05 2021 07 05 2021 © 2021 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2021 cardiovascular disease cGMP mechanotransduction notch signalling pathway rho-associated...
Articles
Karla B. Neves, Hannah E. Morris, Rhéure Alves-Lopes, Keith W. Muir, Fiona Moreton, Christian Delles, Augusto C. Montezano, Rhian M. Touyz
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (6): 753–773.
Published: 17 March 2021
... stress. We identify novel pathways underlying the peripheral arteriopathy induced by Notch3 gain-of-function mutation, phenomena that may also be important in cerebral vessels. notch signalling pathway stroke vascular smooth muscle oxidative stress Notch proteins are cell membrane receptors...
Includes: Supplementary data