...Ashley E. Walker; Rachelle E. Kaplon; Gary L. Pierce; Molly J. Nowlan; Douglas R. Seals Habitual aerobic exercise prevents age-related impairments in endothelium-dependent dilation (EDD). We have hypothesized that the pro-inflammatory transcription factor nuclear factor κB (NF-κB) impairs EDD...

... nephropathy miR-29 nuclear factor κB (NF-κB) SMAD3 SMAD7 Sp1 • Pre-treatment with SMAD7 before AngII infusion is able to inhibit progression of hypertensive kidney disease, indicating a preventive role of Smad7 in hypertensive kidney disease. SMAD7 may be therefore be a novel therapeutic...

... Correspondence: Professor Satoru Eguchi (email seguchi@temple.edu ). 28 1 2014 31 1 2014 31 1 2014 © The Authors Journal compilation © 2014 Biochemical Society 2014 angiotensin II (AngII) hypertension inflammation integrin-linked kinase (ILK) kidney nuclear factor κB (NF-κB...

... in the regulation of renal inflammation by modulating the canonical NF-κB pathway, and suggest a potential therapeutic target for inflammatory renal diseases. angiotensin II (AngII) inflammation integrin-linked kinase (ILK) kidney monocyte chemoattractant protein-1 (MCP-1) nuclear factor κB (NF-κB...

.... Furthermore, we have also provided in vitro and in vivo evidence to support that hyperglycaemia-induced HMGB1 release in the kidney may be potentiating inflammation through the TLR2 pathway [ 72 ]. diabetic nephropathy inflammation kidney nuclear factor κB (NF-κB) Toll-like receptor 2 Toll-like...

... 3 7 2013 9 7 2013 9 7 2013 © The Authors Journal compilation © 2014 Biochemical Society 2014 angiotensin II collagen fibrosis inflammation lymphocyte lysyl oxidase (LOX) N -acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) nuclear factor κB (NF-κB) • Ac-SDKP...

...: Professor Derek A. Mann (email derek.mann@newcastle.ac.uk ). 3 11 2009 6 1 2010 2 2 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 fibrosis hepatocellular carcinoma ischaemia/reperfusion injury non-alcoholic fatty liver disease (NAFLD) nuclear factor...

... inflammation intracellular signalling nuclear factor κB (NF-κB) Rel NF-κB (nuclear factor κB)/Rel is a family of ubiquitously expressed transcription factors, which bind a common DNA sequence called the κB-binding site 5′-GGGRNWYYCC-3′ (where R is any purine, Y is any pyrimidine, N is any nucleotide...

... ). 16 9 2005 9 1 2006 17 1 2006 17 1 2006 The Biochemical Society 2006 endothelin-1 (ET-1) ET A gelatinase nuclear factor κB (NF-κB) matrix metalloproteinase (MMP) osteosarcoma Osteosarcoma is the most frequent primary bone malignancy and the third most common...

..., 813 71 Bratislava, Slovak Republic (email olga.pechanova@savba.sk ). 21 7 2005 7 9 2005 20 10 2005 20 10 2005 The Biochemical Society 2006 N -acetylcysteine genetic hypertension nuclear factor κB (NF-κB) nitric oxide synthase reactive oxygen species (ROS...