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Keywords: nuclear factor κB (NF-κB)
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Clin Sci (Lond) (2014) 127 (11): 645–654.
Published: 29 July 2014
...Ashley E. Walker; Rachelle E. Kaplon; Gary L. Pierce; Molly J. Nowlan; Douglas R. Seals Habitual aerobic exercise prevents age-related impairments in endothelium-dependent dilation (EDD). We have hypothesized that the pro-inflammatory transcription factor nuclear factor κB (NF-κB) impairs EDD...
Includes: Supplementary data
Clin Sci (Lond) (2014) 127 (3): 195–208.
Published: 03 April 2014
... regulatory network may be a mechanism by which SMAD7 protects kidney from hypertensive kidney injury. Thus SMAD7 may be a novel therapeutic agent for hypertensive kidney disease. hypertensive nephropathy miR-29 nuclear factor κB (NF-κB) SMAD3 SMAD7 Sp1 • Pre-treatment with SMAD7...
Clin Sci (Lond) (2014) 127 (1): 15–17.
Published: 10 March 2014
... (AngII) hypertension inflammation integrin-linked kinase (ILK) kidney nuclear factor κB (NF-κB) oxidative stress Ubiquitously expressed ILK (integrin-linked kinase) predominantly localizes at focal adhesions to interact with β-integrins. Although ILK was originally considered to be a serine...
Clin Sci (Lond) (2014) 126 (10): 685–694.
Published: 27 January 2014
... inflammation kidney nuclear factor κB (NF-κB) Toll-like receptor 2 Toll-like receptor 4 Diabetic nephropathy is the leading cause of ESKD (end-stage kidney disease), affecting approximately one-third of all patients with diabetes mellitus [ 1 ]. The disease is relentlessly increasing...
Clin Sci (Lond) (2010) 118 (12): 691–705.
Published: 30 March 2010
...: Professor Derek A. Mann (email derek.mann@newcastle.ac.uk ). 3 11 2009 6 1 2010 2 2 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 fibrosis hepatocellular carcinoma ischaemia/reperfusion injury non-alcoholic fatty liver disease (NAFLD) nuclear factor...
Clin Sci (Lond) (2009) 116 (6): 451–465.
Published: 12 February 2009
... The Authors Journal compilation © 2009 Biochemical Society 2009 cancer inflammation intracellular signalling nuclear factor κB (NF-κB) Rel The secondary lymphoid organs, including the lymph nodes, Peyer's patches, MALT and spleen, are sites where organized arrangement of cells allows proximal...
Clin Sci (Lond) (2006) 110 (6): 645–654.
Published: 15 May 2006
... Biosciences) from 0–10 μmol/l in DMEM containing 2.5% (v/v) FCS for various lengths of time [24 h for RT-PCR (reverse transcription–PCR), Northern blotting and Western blotting, and 5 min, 30 min and 4 h for NF-κB (nuclear factor κB) determination]. endothelin-1 (ET-1) ET A gelatinase nuclear factor...
Clin Sci (Lond) (2006) 110 (2): 235–242.
Published: 17 January 2006
... + N -acetylcysteine genetic hypertension nuclear factor κB (NF-κB) nitric oxide synthase reactive oxygen species (ROS) NO (nitric oxide) plays an important role in the maintenance of vascular tone, which affects the level of BP (blood pressure) [ 1 – 3 ]. In various models of hypertension...