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Keywords: nuclear factor κB (NF-κB)
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Articles
Clin Sci (Lond) (2014) 127 (11): 645–654.
Published: 29 July 2014
...Ashley E. Walker; Rachelle E. Kaplon; Gary L. Pierce; Molly J. Nowlan; Douglas R. Seals Habitual aerobic exercise prevents age-related impairments in endothelium-dependent dilation (EDD). We have hypothesized that the pro-inflammatory transcription factor nuclear factor κB (NF-κB) impairs EDD with...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2014) 127 (3): 195–208.
Published: 03 April 2014
.../NF-κB/ miR-29 regulatory network may be a mechanism by which SMAD7 protects kidney from hypertensive kidney injury. Thus SMAD7 may be a novel therapeutic agent for hypertensive kidney disease. hypertensive nephropathy miR-29 nuclear factor κB (NF-κB) SMAD3 SMAD7 Sp1 • Pre...
Articles
Clin Sci (Lond) (2014) 127 (1): 15–17.
Published: 10 March 2014
... nuclear factor κB (NF-κB) oxidative stress Ubiquitously expressed ILK (integrin-linked kinase) predominantly localizes at focal adhesions to interact with β-integrins. Although ILK was originally considered to be a serine/threonine kinase, it appears to be a pseudokinase. ILK forms a signal...
Articles
Clin Sci (Lond) (2014) 127 (1): 19–31.
Published: 10 March 2014
... ILK could be a potential therapeutic target for inflammatory renal diseases. angiotensin II (AngII) inflammation integrin-linked kinase (ILK) kidney monocyte chemoattractant protein-1 (MCP-1) nuclear factor κB (NF-κB) • Chronic kidney disease is reaching epidemic proportions...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2014) 126 (10): 685–694.
Published: 27 January 2014
... 2014 diabetic nephropathy inflammation kidney nuclear factor κB (NF-κB) Toll-like receptor 2 Toll-like receptor 4 Diabetic nephropathy is the leading cause of ESKD (end-stage kidney disease), affecting approximately one-third of all patients with diabetes mellitus [ 1 ]. The disease...
Articles
Clin Sci (Lond) (2014) 126 (1): 85–94.
Published: 09 September 2013
... 3 7 2013 9 7 2013 9 7 2013 © The Authors Journal compilation © 2014 Biochemical Society 2014 angiotensin II collagen fibrosis inflammation lymphocyte lysyl oxidase (LOX) N -acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) nuclear factor κB (NF-κB) • Ac-SDKP...
Articles
Clin Sci (Lond) (2010) 118 (12): 691–705.
Published: 30 March 2010
...) nuclear factor κB (NF-κB) regeneration NF-κB (nuclear factor κB) was first described in 1986 as a nuclear transcription factor required for immunoglobulin kappa light chain transcription in B-cells [ 1 ]. Since then it has been demonstrated that NF-κB is constitutively expressed in all cell types...
Articles
Clin Sci (Lond) (2009) 116 (6): 451–465.
Published: 12 February 2009
... inflammation intracellular signalling nuclear factor κB (NF-κB) Rel NF-κB (nuclear factor κB)/Rel is a family of ubiquitously expressed transcription factors, which bind a common DNA sequence called the κB-binding site 5′-GGGRNWYYCC-3′ (where R is any purine, Y is any pyrimidine, N is any nucleotide...
Articles
Clin Sci (Lond) (2006) 110 (6): 645–654.
Published: 15 May 2006
...@umontreal.ca ). 16 9 2005 9 1 2006 17 1 2006 17 1 2006 The Biochemical Society 2006 endothelin-1 (ET-1) ET A gelatinase nuclear factor κB (NF-κB) matrix metalloproteinase (MMP) osteosarcoma Osteosarcoma is the most frequent primary bone malignancy and the third...
Articles
Clin Sci (Lond) (2006) 110 (2): 235–242.
Published: 17 January 2006
..., 813 71 Bratislava, Slovak Republic (email olga.pechanova@savba.sk ). 21 7 2005 7 9 2005 20 10 2005 20 10 2005 The Biochemical Society 2006 N -acetylcysteine genetic hypertension nuclear factor κB (NF-κB) nitric oxide synthase reactive oxygen species (ROS...