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Keywords: oestrogen
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Articles
Clin Sci (Lond) (2016) 130 (14): 1147–1163.
Published: 01 June 2016
... inequalities oestrogen sex testosterone To approach medicine from a gender perspective is a relatively recent attempt to see as an opportunity the fact that the two sexes may have different experiences and manifestations of the same disease. The two sexes may, indeed, present with different symptoms...
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Clin Sci (Lond) (2016) 130 (1): 9–18.
Published: 30 November 2015
... in the development of hypertension in both men and women is an increase in sympathetic nerve activity (SNA). Brain regions important for the regulation of SNA, such as the subfornical organ, the paraventricular nucleus and the rostral ventral lateral medulla, also express specific subtypes of oestrogen receptors...
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Clin Sci (Lond) (2015) 129 (10): 885–893.
Published: 01 September 2015
..., HR correlated inversely ( P <0.05) with HF. In conclusion, ExFHA women demonstrate augmented vagal yet unchanged sympathetic HR modulation, both at rest and during orthostatic stress. Although the role of oestrogen deficiency is unclear, these findings are in contrast with studies reporting...
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Clin Sci (Lond) (2013) 125 (7): 311–318.
Published: 07 June 2013
... Health Initiative or HERS (Heart and Estrogen/progestin Replacement Study) did not provide primary or secondary prevention against cardiovascular events. Men are also thought to be at risk of cardiovascular disease at earlier ages than women, and these mechanisms too are not likely to be as simple...
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Clin Sci (Lond) (2010) 119 (12): 493–513.
Published: 01 September 2010
... for oestrogens, androgens and progestins [ 43 ]. GPCRs (G-protein-coupled receptors) for oestrogen and progesterone have been identified on the cell surface, but remain a subject of controversy. Correspondence: Professor Amparo C. Villablanca (email [email protected] ). 4 5 2010 7 7...
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Clin Sci (Lond) (2010) 118 (6): 375–389.
Published: 15 December 2009
...Hilary V.O. Carswell; I. Mhairi Macrae; Tracy D. Farr Evidence exists for the potential protective effects of circulating ovarian hormones in stroke, and oestrogen reduces brain damage in animal ischaemia models. However, a recent clinical trial indicated that HRT (hormone-replacement therapy...
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Clin Sci (Lond) (2009) 117 (10): 355–364.
Published: 07 September 2009
.... In parallel, we show that castration in rats is followed by a decrease in circulating endothelial progenitor cells, but that testosterone and dihydrotestosterone replacement fails to restore endothelial progenitor cells towards normal levels. This is associated with persistently low oestrogen levels after...
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Clin Sci (Lond) (2006) 111 (2): 107–118.
Published: 13 July 2006
...Shanhong Ling; Paul Komesaroff; Krishnankutty Sudhir Although pre-menopausal women enjoy relative cardiovascular protection, hormone (oestrogen±progestin)-replacement therapy has not shown cardiovascular benefits in post-menopausal women, suggesting that the effects of oestrogens...
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Clin Sci (Lond) (2002) 103 (s2002): 434S–437S.
Published: 01 September 2002
.../reperfusion increased significantly by approx. 2-fold over sham-operated rats, and this elevation was dose-dependently suppressed by the 17β-oestradiol treatment. These results suggest that oestrogen exhibits protective effects against renal dysfunction and tissue injury induced by ischaemia/reperfusion...
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Clin Sci (Lond) (2001) 101 (1): 93–99.
Published: 13 June 2001
... of cardiovascular events in the first year of Key words : coagulation, factor VII, hormone replacement therapy, oestrogen, progestin. Abbreviations : AT, antithrombin; F1 2, fragment 1 2; HDL-C, high-density lipoprotein cholesterol ; HRT, hormone replacement therapy; LDL-C, low-density lipoprotein cholesterol ; TAT...
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Clin Sci (Lond) (2001) 100 (5): 473–479.
Published: 29 March 2001
...Helena TEEDE; Andrea VAN DER ZYPP; Henryk MAJEWSKI Although gender and oestrogen treatment influence production of the vasorelaxant, NO, their influence on factors downstream in the NO signal-transduction pathway, specifically protein kinase G (PKG), remains unknown. We aimed to study the influence...
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Clin Sci (Lond) (2001) 100 (2): 207–213.
Published: 09 January 2001
...Helena J. TEEDE; Barry P. MCGRATH; Alan TURNER; Harry MAJEWSKI The effects of combined oestrogen/progestin hormone replacement therapy (HRT) on platelet aggregation were studied using women on HRT or placebo. The study involved 32 postmenopausal women (aged 50–75 years) who were enrolled...
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Clin Sci (Lond) (2000) 98 (2): 201–207.
Published: 11 January 2000
... appropriate phase during which to test for abnormal vascular responses. INTRODUCTION Chronic pelvic pain in women is a common complaint which affects women of childbearing age [1]. A large proportion of women with this functionally disabling Key words : chronic pelvic pain, menstrual cycle, oestrogen, pelvic...
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Clin Sci (Lond) (1999) 97 (2): 225–232.
Published: 29 June 1999
...Gishel NEW; Stephen J. DUFFY; Karen L. BERRY; Richard W. HARPER; Ian T. MEREDITH Studies have recently demonstrated that long-term oestrogen therapy improves endothelium-dependent and endothelium-independent vasodilatation in the conductance vessels of biological males. We sought to determine...
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Clin Sci (Lond) (1999) 97 (1): 79–84.
Published: 01 June 1999
... isokinetic isometric oestrogen post-menopause progesterone 79Clinical Science (1999) 97, 79 84 (Printed in Great Britain) Changes in muscle strength in women following the menopause: a longitudinal assessment of the efficacy of hormone replacement therapy Julie P. GREEVES*, Nigel T. CABLE*, Thomas...
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Clin Sci (Lond) (1999) 96 (4): 357–364.
Published: 01 April 1999
... strength (maximal voluntary force; MVF), muscle cross-sectional area and bone mineral density were measured. Women entering the trial had oestrogen levels below 150 pmolċl -1 , confirming their post-menopausal hormonal status. In the treated group, MVF increased by 12.4±1.0% (mean±S.E.M.) of initial MVF...
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Clin Sci (Lond) (1985) 69 (2): 235–238.
Published: 01 August 1985
...N. Mishra; C. A. Hamilton; C. R. Jones; C. Leslie; J. L. Reid 1. α 2 -Adrenoceptors on blood platelets have been widely used as a model for α-adrenoceptors in less accessible tissues. 2. The effect of oestrogen (200 μg/day intramuscularly) on α 2 -adrenoceptor number and function was studied...
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Clin Sci (Lond) (1980) 58 (3): 255–257.
Published: 01 March 1980
... in the premenopausal group. 3. Oestrogen therapy reduced both serum and urinary magnesium values in oophorectomized women to premenopausal concentrations. 4. Erythrocyte magnesium concentrations were not affected by menstrual status or oestrogen therapy. 31 8 1979 31 10 1979 © 1980 The Biochemical...
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Clin Sci Mol Med (1978) 54 (2): 193–195.
Published: 01 February 1978
... the skeletal response was measured by photon absorptiometry, bone mineral loss was prevented by both the oestrogen and the progestogen. 3. We confirm that mestranol significantly reduced the urinary output of hydroxyproline-containing peptide, but this did not occur during gestronol therapy, suggesting...
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Clin Sci Mol Med (1975) 48 (5): 457–460.
Published: 01 May 1975
...T. Saruta; R. Nakamura; I. Saito; K. Kondo; S. Matuki 1. A large dose of oestrogen elevated the blood pressure in male Wistar rats. 2. Plasma renin substrate and renin activity increased significantly but plasma renin concentration was unchanged. 3. The increase in blood pressure induced...
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Clin Sci Mol Med (1974) 47 (2): 179–187.
Published: 01 August 1974
... in the mestranol group as compared with the controls, but there was no significant difference in Na e . 5. These findings support the hypothesis that oestrogen-induced fluid retention is the result of primary water retention with secondary redistribution of body sodium. 12 3 1974 © 1974 The Biochemical...