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Keywords: ornithine decarboxylase
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Articles

Is polyamine synthesis involved in the proliferative response of the intestinal epithelium to urogastrone-epidermal growth factor?

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R. A. Goodlad, H. Gregory, N. A. Wright
Journal: Clinical Science
Clin Sci (Lond) (1989) 76 (6): 595–598.
https://doi.org/10.1042/cs0760595
Published: 01 June 1989
... groups given URO-EGF and difluoromethylornithine (DFMO), an inhibitor of the enzyme ornithine decarboxylase (ODC). 2. URO-EGF significantly increased intestinal cell proliferation throughout the gastrointestinal tract. The proliferative response of the colon was particularly pronounced. 3. DFMO reduced...
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Articles

Mechanisms of Structural Vascular Changes in Genetic Hypertension: Analyses on Cultured Vascular Smooth Muscle Cells from Spontaneously Hypertensive Rats

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Yukio Yamori, Takehiro Igawa, Toshimi Kanbe, Masahiro Kihara, Yasuo Nara, Ryoichi Horie
Journal: Clinical Science
Clin Sci (Lond) (1981) 61 (s7): 121s–123s.
https://doi.org/10.1042/cs061121s
Published: 01 December 1981
..., and ornithine decarboxylase (ODC) activity of SMC were increased in SHR and SHRSP in comparison with WKY rats. 4. The application of isoprenaline but not noradrenaline to the culture media increased ODC activity acutely in SMC from WKY rats and this increase was blocked by propranolol. 5. These results indicate...
View articletitled, Mechanisms of Structural Vascular Changes in Genetic Hypertension: Analyses on Cultured Vascular Smooth Muscle Cells from Spontaneously Hypertensive Rats
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