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Keywords: osteoarthritis
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Clin Sci (Lond) (2022) 136 (13): 1053–1069.
Published: 06 July 2022
...Xiao Ma; Dechao Cai; Yakun Zhu; Yao Zhao; Xianbo Shang; Chen Wang; Haotian Zhang; Ashuai Bian; Haoran Yu; Wendan Cheng Osteoarthritis (OA) is a heterogeneous condition characterized by cartilage degradation, subchondral sclerosis, and osteophyte formation, and accompanied by the generation of pro...
Clin Sci (Lond) (2020) 134 (23): 3159–3174.
Published: 09 December 2020
...Zhiyuan Guan; Jialin Jia; Chenggui Zhang; Tiantong Sun; Wang Zhang; Wanqiong Yuan; Huijie Leng; Chunli Song Gut microbiota dysbiosis has been studied under the pathological conditions of osteoarthritis (OA). However, the effect of antibiotic-induced gut flora dysbiosis on OA remains incompletely...
Includes: Supplementary data
Clin Sci (Lond) (2019) 133 (21): 2171–2187.
Published: 08 November 2019
... participatory limitations. Osteoarthritis (OA) is a progressive degenerative joint disease, usually observed at age 40, and not noticed before pain or diagnosis. Although exercise has health benefits, it is unclear whether outdoor jogging in higher PM (standard reference material 1649b, SRM 1649b) concentration...
Clin Sci (Lond) (2019) 133 (16): 1813–1824.
Published: 21 August 2019
... in Osteoarthritis (OA) pathophysiology. Attention was also paid to a further stromal cell type with a peculiar ultrastructure called telocytes (TCs), whose role is far from clarified. Methods: In the present in vitro study, we compared SDSCs isolated from healthy and OA subjects in terms of phenotype, morphology...
Clin Sci (Lond) (2013) 125 (2): 99–108.
Published: 26 March 2013
...Victoria Clérigues; Christopher L. Murphy; Maria Isabel Guillén; Maria José Alcaraz HO-1 (haem oxygenase-1) catalyses the degradation of haem and possesses anti-inflammatory and cytoprotective properties. The role of inflammatory mediators in the pathogenesis of OA (osteoarthritis) is becoming...
Clin Sci (Lond) (2012) 123 (11): 627–634.
Published: 01 August 2012
...David Metcalfe; Alison L. Harte; Mina Olga Aletrari; Nasser M. Al Daghri; Dara Al Disi; Gyanendra Tripathi; Philip G. McTernan OA (osteoarthritis) is a degenerative condition associated with obesity. A number of metabolic explanations have been proposed to explain the association between obesity...
Clin Sci (Lond) (2012) 122 (5): 239–251.
Published: 08 November 2011
...Victoria Clérigues; Maria Isabel Guillén; Francisco Gomar; Maria José Alcaraz IL (interleukin)-1β plays an important role in cartilage extracellular matrix degradation and bone resorption in OA (osteoarthritis) through the induction of degradative enzymes and pro-inflammatory mediators...
Includes: Supplementary data
Clin Sci (Lond) (2007) 113 (3): 149–155.
Published: 02 July 2007
... cytokines IL-1β (interleukin-1β) and TNF-α (tumour necrosis factor-α) or by H 2 O 2 . Synoviocytes from five OA (osteoarthritis) patients were used as controls. Immunoprecipitation assays using two different antibodies showed that RA, but not OA, cells expressed intact Trx80 protein in culture even when...
Clin Sci (Lond) (2001) 101 (6): 593–599.
Published: 26 October 2001
...Ilaria MAZZETTI; Brunella GRIGOLO; Lia PULSATELLI; Paolo DOLZANI; Tania SILVESTRI; Livia ROSETI; Riccardo MELICONI; Andrea FACCHINI Osteoarthritis and rheumatoid arthritis are characterized by focal loss of cartilage due to an up-regulation of catabolic pathways, induced mainly by pro-inflammatory...
Clin Sci (Lond) (1993) 85 (3): 343–351.
Published: 01 September 1993
... course of examination, from the knee joints of patients attending rheumatology and orthopaedic clinics. Fluid was available from 16 patients with osteoarthritis, 18 patients with rheumatoid arthritis, four patients with meniscal tear and one patient each with systemic lupus erythematosis, mono-arthritis...
Clin Sci (Lond) (1989) 76 (1): 113–117.
Published: 01 January 1989
...Gunnar Leivseth; Johnas Torstensson; Olav Reikerås 1. Twenty-five minute daily muscle stretching, perpendicular to the fibre direction of the adductor muscles without movement of the hip, was performed in patients with osteoarthritis of the hip. 2. Before and after treatment hip abduction...
Clin Sci (Lond) (1988) 74 (1): 97–99.
Published: 01 January 1988
... in arthritis. 2. We have quantified nucleosides and bases in synovial fluid and plasma by high-performance liquid chromatography in order to examine whether nucleotide metabolism is increased in patients with rheumatoid arthritis and osteoarthritis. 3. At least ten u.v.-absorbing compounds were detected...
Clin Sci (Lond) (1981) 61 (6): 703–710.
Published: 01 December 1981
... with rheumatoid arthritis. collagenase hydrocortisone indomethacin inhibitor (TIMP) osteoarthritis synovium © 1981 The Biochemical Society and the Medical Research Society 1981 6 3 1981 27 4 1981 Clinical Science (1981) 61,703-710 703 Production of collagenase and inhibitor (TIMP...
Clin Sci (1972) 42 (3): 383–393.
Published: 01 March 1972
...W. C. Dick; K. E. Collins; W. W. Buchanan 1. The uptake of a low dose of intravenously administered 99m Tc over the distal and proximal interphalangeal joints was found to be lower in normal subjects than in patients suffering from rheumatoid arthritis, osteoarthritis and psoriatic arthritis. 2...