...M. Hatch; N. D. Vaziri 1. The purpose of the present study was to examine the effects of various diuretics on intestinal oxalate transport. Transmural oxalate fluxes were measured across isolated, short-circuited tissue segments removed from rabbits and placed in Ussing chambers. 2. The net...

.... 2. Serum concentrations were measured pre- and post-dialysis at the end of each study period. The whole dialysate was used for the determination of the overall calcium and oxalate removal by dialysis. The degree of saturation with calcium oxalate mono-hydrate was estimated by a computer program...

...Giovanni Gambaro; Massimo Vincenti; Francesco Marchini; Angela D'Angelo; Bruno Baggio 1. The demonstration of an inheritable anomaly of erythrocyte oxalate transport in ‘primary’ calcium nephrolithiasis suggested that this disease might be a generalized metabolic disorder characterized by a defect...

...Bruno Baggio; Giovanni Marzaro; Giovanni Gambaro; Francesco Marchini; Hibbard E. Williams; Arturo Borsatti 1. This study was performed to test the hypothesis that glycosaminoglycans may play an important role in the observed abnormalities in oxalate flux seen in patients with calcium oxalate...

... to contribute to the formation of oxalate from its immediate precursors, glycollate and glyoxylate, but the relative contributions of each enzyme to endogenous oxalate production is not known. 2. In rat liver homogenates, [ 14 C]oxalate production from labelled glycollate is halved and that from labelled...

... of having this disease and 11 patients in whom no information was available as to their oxalate metabolism. 2. Oxalate concentrations in haemodialysate fractions and blood samples, taken before and after dialysis, were determined. 3. The patient with primary hyperoxaluria had a plasma oxalate concentration...

...R. W. E. Watts; N. Veall; P. Purkiss; M. A. Mansell; E. F. Haywood 1. We have measured glomerular filtration rate (GFR), extracellular fluid volume (ECF), oxalate distribution volume (OxDV), plasma oxalate concentration (P Ox. ), plasma total clearance of oxalate (P C Ox. ), oxalate metabolic pool...

...Stephen B. Erickson; Kerry Cooper; Arthur E. Broadus; Lynwood H. Smith; Peter G. Werness; Henry J. Binder; John W. Dobbins 1. The effect of 1,25-dihydroxyvitamin D [1,25-(OH) 2 D] on dietary oxalate absorption and postprandial urine supersaturation with calcium oxalate was determined in 11 normal...

...R. W. E. Watts; N. Veall; P. Purkiss 1. We have measured the plasma oxalate concentration (P Ox ), urinary oxalate excretion (U Ox ), oxalate equilibrium distribution volume (ODV), oxalate metabolic pool size [(ODV) × (P Ox )], total plasma oxalate clearance (PC Ox ), renal (or dialyser) oxalate...

...R. W. E. Watts; N. Veall; P. Purkiss 1. We have measured the total plasma clearance, renal clearance and equilibrium distribution volume of [ 14 C]oxalate, and the urinary oxalate excretion rate and plasma oxalate levels at approximately 6 month intervals for up to 2.5 years in five patients...

...J. A. C. Prenen; P. Boer; E. J. Dorhout Mees; H. J. Endeman; S. M. Spoor; H. Y. Oei 1. The renal clearance of [ 14 C]oxalate was assessed by the constant-infusion technique and single-injection technique (plasma sampling only: one-compartment and two-compartment model; plasma and urine sampling...

...A. M. Finch; G. P. Kasidas; G. A. Rose 1. Urinary composition was studied in nine healthy adults on unrestricted diet and low-oxalate diet with and without individual oxalate-rich foods. 2. Urine oxalate was constant on the low-oxalate and constant high-oxalate diets and only fluctuated greatly...

... phosphate and an increase in the urinary excretion of oxalic acid and uric acid, but these changes were all fully reversible when EHDP was stopped. 4. The average rate of stone formation per patient per year decreased from 2·4 to 0·2 during treatment with EHDP and remained low during the following 24 months...

... an oral load of oxalate. 29 10 1976 16 3 1977 © 1977 The Biochemical Society and the Medical Research Society 1977 calcium crystalluria inhibitors oxalate pyrophosphate urolithiasis Clinical Science and Molecular Medicine (1977) 53, 141-148. The role of inhibitors and other...

...W. G. Robertson; M. Peacock; R. W. Marshall; R. Speed; B. E. C. Nordin 1. A retrospective cross-sectional study was carried out on data derived from single 24 h urine collections from 246 male idiopathic calcium stone-formers. 2. The daily urine volume and pH and the excretions of calcium, oxalate...