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Keywords: oxidative injury
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Articles

Periodontal disease is associated with lower antioxidant capacity in whole saliva and evidence of increased protein oxidation

Dean V. SCULLEY, Simon C. LANGLEY-EVANS
Journal: Clinical Science
Clin Sci (Lond) (2003) 105 (2): 167–172.
https://doi.org/10.1042/CS20030031
Published: 01 August 2003
...Dean V. SCULLEY; Simon C. LANGLEY-EVANS The aim of this cohort study was to determine whether periodontitis and gingivitis are associated with impaired salivary antioxidant status and increased oxidative injury. One hundred and twenty-nine patients attending a routine dental check-up were recruited...
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Articles

Membrane structural changes support the involvement of mitochondria in the bile salt-induced apoptosis of rat hepatocytes

Susana SOLÁ, Maria A. BRITO, Dora BRITES, José J.G. MOURA, Cecília M.P. RODRIGUES
Journal: Clinical Science
Clin Sci (Lond) (2002) 103 (5): 475–485.
https://doi.org/10.1042/cs1030475
Published: 11 October 2002
... at the membrane—water surface in mitochondria exposed to hydrophobic bile salts, including modified lipid polarity and fluidity, altered protein order and increased oxidative injury. UDC, TUDC and cyclosporin A almost completely abrogated DC- and GCDC-induced membrane perturbations. We conclude that the toxicity...
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