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Keywords: p-glycoprotein
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Clin Sci (Lond) (2021) 135 (11): 1333–1351.
Published: 02 June 2021
... care. With interdisciplinary collaboration among oncologists, cardiologists, and pharmacists, there is potential to prevent and reduce drug-related toxicities of treatments. The cytochrome P450 (CYP450) family of enzymes and the P-glycoprotein (P-g) transporter play a crucial role in drug metabolism...
Clin Sci (Lond) (2017) 131 (15): 1831–1840.
Published: 05 July 2017
...Yasmin Pontual; Vanessa S.S. Pacheco; Sérgio P. Monteiro; Marcel S.B. Quintana; Marli J.M. Costa; Valeria C. Rolla; Liane de Castro Polymorphism in the ABCB1 gene encoding P-glycoprotein, a transmembrane drug efflux pump, contributes to drug resistance and has been widely studied. However...