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Clin Sci (Lond) (2016) 130 (24): 2257–2265.
Published: 04 November 2016
... thought to be the underlying cause of a variety of heritable pain disorders. This review provides an overview of the current literature concerning the role of VGSCs in the generation of pain and heritable pain disorders. 1 Both authors have contributed equally to the manuscript...
Clin Sci (Lond) (2006) 110 (2): 175–191.
Published: 17 January 2006
... disease states, including Alzheimer's disease, depression, pain and asthma. In addition, the role of BDNF (brain-derived neurotrophic factor) in synaptic plasticity and memory formation is discussed. Unlike the other neurotrophins, BDNF is secreted in an activity-dependent manner that allows the highly...
Clin Sci (Lond) (2002) 103 (3): 311–321.
Published: 15 August 2002
... Society and the Medical Research Society © 2002 2002 blood flow diabetic rat endothelium-dependent relaxation endothelium-derived hyperpolarizing factor nerve conduction neuropathy nitric oxide pain protein kinase C sensory thresholds 311Clinical Science (2002) 103, 311 321 (Printed in...
Clin Sci (Lond) (2000) 98 (1): 15–20.
Published: 19 November 1999
...Björn E. ERIKSSON; Bita SADIGH; Jan SVEDENHAG; Christer SYLVÉN It has been proposed that adenosine mediates ischaemic pain in humans. Patients with cardiac Syndrome X are hypersensitive to potential pain stimuli, including adenosine. On the other hand, recent findings suggest that low-dose...
Clin Sci (Lond) (1998) 96 (1): 117–125.
Published: 01 January 1999
...Massimo PAGANI; Daniela LUCINI Chronic fatigue syndrome is a debilitating illness of unknown aetiology, with estimated levels of prevalence of up to about 8.7/100 000 in the U.S.A. Like pain fatigue it is a personal, emotionally rich experience, which may originate from peripheral or central sites...
Clin Sci (Lond) (1993) 84 (3): 305–311.
Published: 01 March 1993
... substance P and calcitonin-gene-related peptide have been measured in patients with diabetic polyneuropathy to determine whether differences in small primary sensory afferent activity are related to the presence or absence of painful symptoms. 2. Calcitonin-gene-related peptide was undetectable in the...
Clin Sci (Lond) (1991) 81 (6): 793–798.
Published: 01 December 1991
...Birger Fagher; Mario Monti; Peter Nilsson-Ehle; Björn Åukesson 1. Gluteal adipose tissue was examined in 13 patients with generalized adiposis dolorosa, a clinical condition characterized by painful adiposity with a chronic intractable course. The total metabolic activity of fat cells, isolated by...
Clin Sci (Lond) (1988) 74 (5): 553–557.
Published: 01 May 1988
...D. J. Newham; D. A. Jones; G. Ghosh; P. Aurora 1. The effect of muscle length on the development of muscle pain and fatigue has been studied. 2. Eight normal young adults performed maximal eccentric contractions of the elbow flexors. The muscles of one arm were exercised at short length, and the...
Clin Sci (Lond) (1981) 60 (2): 145–155.
Published: 01 February 1981
... normal subjects. The contribution of pain to the cardiorespiratory changes was also investigated in normal subjects by using hypnosis to relieve pain during and after isometric exercise. 2. The patients and normal subjects performed fatiguing isometric forearm exercises on a handgrip dynamometer on at...