... exocrine pancreatic disease is similar between humans and pigs with CF, the CF pig model has the potential to contribute significantly to the understanding of CFRD pathogenesis. We determined the structure of the endocrine pancreas in fetal, newborn and older CF and non-CF pigs and assessed endocrine...

... The Biochemical Society 2005 liver metaplasia neoplasia pancreas regeneration transdifferentiation Adequate replacement of tissues and organs following injury or disease still remains a major challenge in medicine. Since the first cornea transplant in 1905, major advances have been made...

... data and taken with the results of that study suggest that the pancrease is about five-fold more sensitive than the gallbladder to circulating CCK-8. These results therefore support those of Malagelada et al. [12], who found the pancreas to be eight-fold more sensitive than the gallbladder to exogenous...

.... Activities of aromatase, which converts testosterone into oestradiol, comparable with those found in pre-menopausal uterus ( P < 0.5) were found in all seven samples of pancreatic carcinoma tissue, and in a pooled sample of foetal pancreas. Measurable but significantly lower activities ( P < 0.001...

...P. E. T. Isaacs; J. S. Whitehead; Y. S. Kim 1. The distribution of muscarinic cholinergic receptors (mAChR), detected by atropine-inhibitable binding of [ 3 H]quinuclidinyl benzilate, was examined in membrane fractions of pancreas, small intestinal muscle, mucosa, villi and crypts of sham-operated...

.... There was more DNA per g of pancreas, indicating that unless there were changes in tissue water cellular hypotrophy must have accompanied the hypoplasia. 3. Pancreatic RNA also decreased significantly after 3–10 days of total parenteral nutrition, suggesting reduced protein synthesis. 4. Bacterial counts (log...

... in the distal tubular cells of the rat kidney. Attempts to localize kallikrein in the human kidney were unsuccessful. 4. In the rat and human pancreas, kallikrein was found as a pro-enzyme in the acinar cells. © 1979 The Biochemical Society and the Medical Research Society 1979 kallikrein kidney...

... and the Medical Research Society 1978 metabolism pancreas radioimmunoassay secretin Clinical Science and Molecular Medicine (1978) 54,61-68 Elimination of porcine secretin in pigs J. FAHRENKRUG, O. B. SCHAFFALITZKY DE MUCKADELL AND J. J. HOLST Department of Clinical Chemistry, Bispebjerg Hospital...

... in pancreatic juice, in addition to the expected stimulation of mucosal secretion. 3. Intravenously injected cholera toxin failed to elicit a secretory flow from the pancreas and biliary tract. 4. The time-course of the enhanced secretory flow from pancreas and biliary tract after intraluminal cholera toxin...