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Keywords: peroxiredoxins
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (1): 73–74.
Published: 14 January 2020
...Natalia López-Andrés We thank Ahmed et al. for their letter regarding our study ‘Galectin-3 down-regulates antioxidant peroxiredoxin-4 in human cardiac fibroblasts’ [ 1 ]. As emphasized by Ahmed et al., Prx-4 levels decrease [ 2 ] whereas MFN-2, OPA-1 and PGC-1α levels increase [ 3 ] in dilated...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (1): 71–72.
Published: 14 January 2020
... peroxiredoxin-4 (Prx-4) in cardiac fibroblasts. Authors concluded that ‘antioxidant activity of Prx-4 had been identified as a protein down-regulated by Gal-3. Moreover, Gal-3 induced a decrease in total antioxidant capacity which resulted in a consequent increase in peroxide levels and oxidative stress markers...
Articles
Jaime Ibarrola, Vanessa Arrieta, Rafael Sádaba, Ernesto Martinez-Martinez, Amaia Garcia-Peña, Virginia Alvarez, Amaya Fernández-Celis, Alicia Gainza, Enrique Santamaría, Joaquin Fernández-Irigoyen, Victoria Cachofeiro, Guillermo Zalba, Renaud Fay, Patrick Rossignol, Natalia López-Andrés
Journal:
Clinical Science
Clin Sci (Lond) (2018) 132 (13): 1471–1485.
Published: 18 July 2018
... identified that Gal-3 down-regulated the antioxidant peroxiredoxin-4 (Prx-4) in cardiac fibroblasts. In parallel, Gal-3 increased peroxide, nitrotyrosine, malondialdehyde, and N-carboxymethyl-lysine levels and decreased total antioxidant capacity. Gal-3 decreased prohibitin-2 expression without modifying...
Includes: Supplementary data