... (tumour necrosis factor α) and other inflammatory cytokines. There was no significant effect of insulin resistance and NASH on whole body rate of protein turnover [phenylalanine R a (rate of appearance)] and on the rate of urea synthesis. The rates of methylation of homocysteine and transmethylation...

... volunteers. Six healthy male subjects were studied in the post-absorptive state before and during 4 h following an intravenous endotoxin bolus (4 ng/kg of body weight). Primed continuous infusion of [ 2 H 5 ]phenylalanine and [ 2 H 3 ]3-methylhistidine in combination with sampling from the radial artery...

... techniques. 2. A primed constant infusion of l -[2,6- 3 H]phenylalanine was given to male Lewis rats after 16, 40, 64 and 112 h starvation. Protein synthesis rates of the gastrocnemius muscle were measured by the incorporation technique and compared with hindquarter protein turnover calculated in a two...

.... It was hypothesized that Vaminolact was deficient in total aromatic amino acids, so a third group received a human-milk-patterned amino acid solution with added phenylalanine. 2. The piglets were on total parenteral nutrition for 8 days from day 2 or 3 of life. They all received a total energy intake of 1040 kJ day...

... 5 ]phenylalanine balances were measured during a primed, continuous infusion of the two amino acids during the fasting and feeding phase on the second day. 2. Increasing fasting N losses were observed (47 +7, 60+6, 95+15 and 140+36 mg day −1 kg −1 ) on the four intakes, with corresponding increasing...

..., [ 2 H 5 ]phenylalanine and [ 2 H 2 ]tyrosine kinetics, were measured during an 8h primed, continuous infusion during the fasting and feeding phase together with fed-state N turnover assessed with [ 15 N]glycine after 12 days of adaptation to diets containing 0.36 (LP), 0.77 (MP), 1.59 (GP) and 2.07...

...P. J. Pacy; G. N. Thompson; D. Halliday 1. The aims of this study were twofold: (i) to investigate the ability of a recently described [ 2 H 5 ]phenylalanine method for quantifying whole-body protein turnover during acute physiological perturbation; (ii) to determine specifically whether...

...G. A. Young; F. M. Parsons 1. Plasma tyrosine and phenylalanine were measured in patients with chronic renal failure and in normal subjects. Plasma tyrosine to phenylalanine ratio was greatly decreased in patients with creatinine clearance less than 16 ml/min, suggesting an impairment...