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Keywords: plasma
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Articles
Clin Sci (Lond) (2012) 122 (8): 385–400.
Published: 14 December 2011
...). In normolipidaemic plasma, approximately 84%, 11% and 5% of BAs were recovered in the LPDS (lipoprotein-depleted serum), HDL and the combined LDL (low-density lipoprotein)/VLDL (very-low-density lipoproteins) fraction respectively. Conjugated BAs were slightly over-represented in HDL. For C4, the respective...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2010) 118 (5): 333–339.
Published: 23 November 2009
...Allan D. Sniderman; Jacqueline De Graaf; Patrick Couture; Ken Williams; Robert S. Kiss; Gerald F. Watts The objectives of this analysis are to re-examine the foundational studies of the in vivo metabolism of plasma LDL (low-density lipoprotein) particles in humans and, based on them, to reconstruct...
Articles
Clin Sci (Lond) (2009) 116 (9): 721–730.
Published: 02 April 2009
... and high mortality rate. Its pathophysiology and molecular mechanisms are complicated and remain poorly understood. In the present study, we performed a proteomics investigation to characterize early host responses to sepsis as determined by an altered plasma proteome in a porcine model of peritonitis...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2005) 108 (5): 457–462.
Published: 22 April 2005
...Jenny MYERS; Rachel IRVINE; Joanna GILLHAM; Maureen MACLEOD; Gary MIRES; Michael TAGGART; Philip BAKER In order to facilitate characterization of the circulating factor(s) in pre-eclampsia, the present study aimed to determine whether plasma from women with pre-eclampsia, which induces attenuated...
Articles
Clin Sci (Lond) (2003) 104 (1): 1–5.
Published: 10 December 2002
...Kazuhito TOTSUNE; Kazuhiro TAKAHASHI; Zenei ARIHARA; Masahiko SONE; Sadayoshi ITO; Osamu MURAKAMI Urotensin II (UII) is the most potent vasoconstrictor peptide, whereas it acts as a vasodilator on some arteries. We studied plasma levels of UII in diabetic patients with normal serum creatinine...
Articles
Clin Sci (Lond) (2001) 100 (1): 117–126.
Published: 13 December 2000
...Hiroshi ASAKAWA; Toshio NISHIKIMI; Takeshi SUZUKI; Suomi HARA; Yusuke TSUBOKOU; Hiroshi YAGI; Akihisa YABE; Noriaki TSUCHIYA; Shigeo HORINAKA; Kenji KANGAWA; Hiroaki MATSUOKA Adrenomedullin (AM) has vasodilatory, diuretic and natriuretic actions. Two molecular forms of AM circulate in human plasma...
Articles
Clin Sci (Lond) (1999) 97 (3): 255–258.
Published: 15 July 1999
...P. F. DOWNIE; S. TALWAR; I. B. SQUIRE; J. E. DAVIES; D. B. BARNETT; L. L. NG Plasma concentrations of N-terminal pro-brain natriuretic peptide (NT-proBNP) are raised in patients with left ventricular dysfunction. Measurement of this peptide has a potential diagnostic role in the identification...
Articles
Clin Sci (Lond) (1999) 96 (4): 373–380.
Published: 01 April 1999
...D. HUGHES; S. TALWAR; I. B. SQUIRE; J. E. DAVIES; L. L. NG Measurement of plasma levels of brain natriuretic peptide (BNP) has been used to assess left ventricular dysfunction and prognosis. Levels of the N-terminus of the precursor of BNP (NT-proBNP) have been reported to be elevated to a greater...
Articles
Clin Sci (Lond) (1994) 87 (3): 319–322.
Published: 01 September 1994
...Kazuhito Totsune; Kazuhiro Takahashi; Osamu Murakami; Fumitoshi Satoh; Masahiko Sone; Toraichi Mouri 1. C-type natriuretic peptide is a neuropeptide, which is also produced by the vascular endothelial cells. Plasma immunoreactive C-type natriuretic peptide concentrations in patients with various...
Articles
Clin Sci (Lond) (1992) 83 (4): 477–482.
Published: 01 October 1992
...N. Krivoy; H. Schlüter; M. Karas; W. Zidek 1. Human plasma was incubated with tissue kallikrein from porcine pancreas, dialysed to obtain a fraction with a molecular mass < 10 kDa and further purified by reverse-phase chromatography. 2. Vasopressor activity in the fractions obtained was tested...
Articles
Clin Sci (Lond) (1992) 83 (2): 205–211.
Published: 01 August 1992
...Toraichi Mouri; Masahiko Sone; Kazuhiro Takahashi; Keiichi Itoi; Kazuhito Totsune; Yutaka Hayashi; Sumio Hasegawa; Makoto Ohneda; Osamu Murakami; Yukio Miura; Ryuichi Katakura; Shinro Tachibana; Masaru Maebashi 1. We investigated the usefulness of neuropeptide Y as a plasma marker...
Articles
Clin Sci (Lond) (1992) 82 (1): 113–116.
Published: 01 January 1992
...C. C. T. Smith; B. N. C. Prichard; D. J. Betteridge 1. Plasma and platelet free catecholamine concentrations were measured in 22 normal subjects and in 10 treated and 11 untreated patients with heterozygous familial hypercholesterolaemia. 2. Plasma noradrenaline concentrations were significantly...
Articles
Clin Sci (Lond) (1990) 79 (4): 331–337.
Published: 01 October 1990
...J. Bergström; P. Fürst; E. Vinnars 1. The effect of a protein-free meal and a protein-rich meal on the concentration of free amino acids in plasma and muscle tissue was studied in eight healthy subjects. The energy content of the protein-free meal was 3800 kJ. The protein-rich meal was identical...
Articles
Clin Sci (Lond) (1989) 77 (5): 573–579.
Published: 01 November 1989
...M. G. Buckley; G. A. Sagnella; N. D. Markandu; D. R. J. Singer; G. A. MacGregor 1. Plasma levels of immunoreactive N -terminal pro-atrial natriuretic peptide ( N -terminal ANP) have been measured in 25 normal subjects, 29 patients with essential hypertension, six cardiac transplant recipients...
Articles
Clin Sci (Lond) (1989) 76 (4): 439–446.
Published: 01 April 1989
...Arne Høj Nielsen; Arne Johannessen; Knud Poulsen 1. The plasma concentration of inactive renin was two-to three-fold higher in male than in female mice independently of whether mice of strains with low (BALB/c) or high (Theiller) content of active renin in the submandibular salivary glands were...
Articles
Clin Sci (Lond) (1987) 73 (5): 501–505.
Published: 01 November 1987
...M. Gleeson; J. D. Robertson; R. J. Maughan 1. The response of circulating leucocytes with regard to changes in number, proportion of granulocytes and lymphocytes, as well as changes in the ascorbic acid (AA) concentration of plasma and isolated lymphocytes, were studied in nine men who ran a 21 km...
Articles
Clin Sci (Lond) (1987) 72 (1): 103–112.
Published: 01 January 1987
...A. Gorchein; R. Webber 1. ô-Aminolaevulinic acid (ALA) was determined by g.l.c. with electron-capture detection. Normal plasma level was 92 nmol/l ( sd = 39, n = 89, range 24–270 nmol/l). 2. ALA was undetectable in 35 of 53 samples of normal cerebrospinal fluid (limit of assay 2 nmol/l). The mean...
Articles
Clin Sci (Lond) (1986) 71 (1): 57–60.
Published: 01 July 1986
... that cerebrospinal fluid from patients with infantile and juvenile neuronal ceroid-lipofuscinosis were less protective against superoxide radical-induced hydroxyl radical formation compared with controls [3]. 2. The content of superoxide dismutase isoenzymes in cerebrospinal fluid and in plasma from patients...
Articles
Clin Sci (Lond) (1983) 64 (3): 333–340.
Published: 01 March 1983
...R. A. Harkness; R. J. Simmonds; S. B. Coade 1. After decreasing muscle ATP by a 2 min period of intense exercise, we have studied purine metabolism by using high-pressure liquid chromatography. 2. A major increase in hypoxanthine concentration in plasma and urine was found with increases...
Articles
Clin Sci (Lond) (1982) 62 (2): 177–181.
Published: 01 February 1982
...D. P. Mikhailidis; A. M. Mikhailidis; M. L. Woollard; P. Dandona 1. The rate of decay of the platelet anti-aggregatory activity of prostacyclin in plasma and buffer solutions was investigated. 2. Platelet anti-aggregatory activity of prostacyclin was more stable in plasma than in buffer solutions...
Articles
Clin Sci (Lond) (1981) 61 (6): 671–678.
Published: 01 December 1981
...J. D. Barrett; P. Eggena; J. F. Krall; M. P. Sambhi 1. Renin-like enzymes have been isolated from aorta, plasma and kidney tissue of the rat. The enzymes have been compared with respect to pH optima, molecular weight and isoelectric points. 2. Two distinct molecular-weight forms were isolated from...
Articles
Clin Sci (Lond) (1979) 56 (5): 427–432.
Published: 01 May 1979
...P. Möller; J. Bergström; S. Eriksson; P. Fürst; K. Hellström 1. The concentrations of electrolytes and free amino acids in plasma and the quadriceps femoris muscle were studied in ten apparently healthy elderly men, 52–77 years of age. The results were compared with those previously recorded...
Articles
Clin Sci Mol Med (1973) 45 (6): 827–832.
Published: 01 December 1973
...T. Palmer; Mary A. Rossiter; B. Levin; V. G. Oberholzer 1. After ingestion of up to 1–2 g of protein/kg body weight by adults, plasma concentrations of all amino acids, including glutamine and glutamic acid, rose to a maximum within 5 h. 2. The increases in concentration depended on the amount...
Articles
Clin Sci Mol Med (1973) 45 (5): 607–623.
Published: 01 November 1973
...T. P. Jowett; J. D. H. Slater; R. D. Piyasena; R. P. Ekins 1. A rapid, robust, accurate and sensitive radioimmunoassay procedure is described for the measurement of plasma and urinary aldosterone. 2. A new, simple method is validated for the separation of free from bound moieties which has general...
Articles
Clin Sci Mol Med (1973) 45 (3): 411–415.
Published: 01 September 1973
...R. Fraser; Sheena Guest; Jessie Young 1. Two techniques for estimating plasma aldosterone concentration are compared by means of repeated assays of a plasma pool and also by analysis of a wide range of plasma samples. 2. No significant difference was found in the results obtained by the methods...
Articles
Clin Sci Mol Med (1973) 45 (1): 115–127.
Published: 01 July 1973
...R. D. Gordon; E. M. Symonds; E. G. Wilmshurst; C. G. K. Pawsey 1. In a prospective study involving fifty-six women, measurements of body weight, urinary creatinine, sodium and potassium and plasma sodium, potassium and renin activity were made in mid-pregnancy and at 36 weeks. The effect of sodium...