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Keywords: platelet
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Articles
Clin Sci (Lond) (2020) 134 (16): 2161–2175.
Published: 24 August 2020
... emerging evidence has shown that mitochondrial transplantation is a potential and effective strategy that can reduce brain injury and associated disorders. Platelets are abundant in blood and can be considered a readily available source of small-size mitochondria. These cells can be easily acquired from...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2012) 123 (10): 591–600.
Published: 23 July 2012
... from arterial diseases. We hypothesized interactions between prasugrel and enhanced vWF (von Willebrand Factor) release in a model of systemic inflammation, and compared the pharmacodynamic effects of prasugrel against placebo on agonist-induced platelet aggregation and shear-induced platelet plug...
Articles
Clin Sci (Lond) (2010) 118 (5): 359–366.
Published: 01 December 2009
... randomized to treatment with either atorvastatin or placebo; 20 normolipidaemic patients were also studied. Platelet nitrite, NO and superoxide were examined as was the cellular distribution of the GTPases Rho and Rac at baseline and after 8 weeks of treatment. Following atorvastatin therapy, platelet NO was...
Articles
Clin Sci (Lond) (2004) 107 (4): 391–397.
Published: 24 September 2004
... relaxation and platelet function. Although the concentration of intracellular L -arginine is well above the K m for NO synthesis, in many cells and pathological conditions the transport of L -arginine is essential for NO production ( L -arginine paradox). The present study was designed to investigate the...
Articles
Clin Sci (Lond) (2002) 102 (1): 99–105.
Published: 10 December 2001
... -nitrosocysteine, S -nitrosoglutathione and S -nitrosoalbumin, in which R is an amino acid, polypeptide and protein respectively. RSNOs have anti-platelet properties, a theoretical role in the treatment of asthma and the potential to be used as agents to treat infectious diseases ranging from the common cold to...
Articles
Clin Sci (Lond) (1998) 94 (4): 437–445.
Published: 01 April 1998
...Marcus K. Ilton; Marcia L. Taylor; Neil L. A. Misso; Philip J. Thompson; Joseph Hung 1. Close contact between platelets and neutrophils modulates their cellular interactions in thrombotic and inflammatory states, with stimulation of P-selectin expression on platelets by agonists such as thrombin...
Articles
Clin Sci (Lond) (1989) 76 (6): 631–635.
Published: 01 June 1989
...K. Pritchard; A. E. G. Raine; C. C. Ashley; L. M. Castell; V. Somers; C. Osborn; J. G. G. Ledingham; J. Conway 1. Fifty-two normotensive and essential hypertensive subjects were studied. Intracellular free calcium concentration ([Ca 2+ ] i ) was measured in lymphocytes (37 subjects) and platelets...
Articles
Clin Sci (Lond) (1989) 76 (6): 603–607.
Published: 01 June 1989
...C. C. T. Smith; A. P. Wilson; B. N. C. Prichard; D. J. Betteridge 1. Endogenous noradrenaline release from washed platelets incubated under resting conditions and in the presence of thrombin was examined in 14 normal subjects and 10 subjects with type 1 (insulin-dependent) diabetes. 2. Irreversible...
Articles
Clin Sci (Lond) (1988) 75 (2): 221–224.
Published: 01 August 1988
...Susan M. Barr; Kennedy R. Lees; Daniel D. McBryan; James Reid; Elizabeth Farish; Peter C. Rubin 1. A positive correlation between blood pressure and platelet intracellular free calcium concentration ([Ca 2+ ] i ) has been reported. We examined the effect of acute changes in blood pressure...
Articles
Clin Sci (Lond) (1987) 73 (1): 109–116.
Published: 01 July 1987
...K. Berntorp; F. Lindgäurde; I. Mattiasson 1. The rate constants for the ouabain- and frusemide-sensitive 22 Na + efflux, the number of [ 3 H]ouabain binding sites and the effect of plasma on [ 3 H]ouabain binding were determined in platelets, as were blood pressure (BP) and serum urate...
Articles
Clin Sci (Lond) (1987) 72 (4): 467–473.
Published: 01 April 1987
...Serge Adnot; Nicolas Ferry; Jacques Hanoune; Marie-Use Lacombe 1. Plasmin was recently reported to inhibit platelet aggregation [1]. We report here on the interaction of plasmin with the adenylate cyclase system of human platelets. Human plasmin caused a dose-and time-dependent increase in...
Articles
Clin Sci Mol Med (1975) 49 (2): 115–120.
Published: 01 August 1975
...J. C. Ferguson; N. Mackay; J. A. D. Philip; D. J. Sumner 1. Simultaneous platelet and fibrinogen survival studies were carried out on a group of seven normal persons and eleven diabetic patients. 2. Survival time was calculated: (a) by measuring the interval between 50% of the maximum radioactivity...