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Keywords: poly(ethylene glycol)
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Clin Sci (Lond) (2008) 114 (2): 123–130.
Published: 11 December 2007
... compilation © 2008 Biochemical Society 2008 Attaching PEG [poly(ethylene glycol)] to proteins (PEGylation) increases their intravascular retention time [ t ½ (half-life)] by decreasing physiological turnover (e.g. protecting against proteolysis) and their antigenicity [ 1 ]. For example, PEGylation...