... hypertension which had not responded satisfactorily to other treatment. 3. Patients were treated initially with prazosin; polythiazide, or polythiazide plus tolamolol, were added when necessary. 4. A satisfactory blood pressure response to prazosin alone, or prazosin in dual or triple combination therapy...

... and in combination with a diuretic. The effect on blood pressure is the same in the supine and standing position. © 1975 The Biochemical Society and the Medical Research Society 1975 hypertension polythiazide prazosin renin spontaneously hypertensive rats Clinical Science and Molecular Medicine (1975...

...P. Lund-Johansen 1. The effects of hypotensive therapy with three separate diuretics, methyldopa and clonidine were separately assessed. 2. All the treated groups showed a significant drop in blood pressure. 3. Polythiazide and hydrochlorothiazide each produced a significant fall in total...