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Keywords: potassium
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (2001) 101 (2): 121–130.
Published: 18 June 2001
...Sunil BHANDARI; Malcolm HUNTER Potassium channels are ubiquitous, being present in all living organisms. These proteins share common structural elements, which confer common functional features. In general, all K + channels have a high selectivity for K + , and are blocked by cations of similar...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2001) 101 (1): 37–43.
Published: 24 May 2001
...Zoltán SZABÓ; Hans ARNQVIST; Erik HÅKANSON; Lennart JORFELDT; Rolf SVEDJEHOLM The effects of glucose–insulin–potassium (GIK) on cardiac metabolism have been studied previously in non-diabetic patients after cardiac surgery. Although patients with diabetes mellitus can be expected to benefit most...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1998) 95 (4): 453–458.
Published: 01 October 1998
... and potassium status, supporting similar observations in experimental animals. Correspondence : Professor John V. Jones. 23 1 1998 1 6 1998 26 6 1998 The Biochemical Society and the Medical Research Society © 1998 1998 arrhythmia left ventricular dilation left ventricular...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1998) 95 (1): 3–17.
Published: 01 July 1998
.... ATPase catecholamines digitalis heart insulin muscle potassium sodium thyroid hormones training 3Clinical Science (1998) 95, 3 17 (Printed in Great Britain) + R E V I E W Clinical and therapeutic significance of the Na+,K+ pump* Torben CLAUSEN Department of Physiology, University of Aarhus...
Articles
Gaudenz Hafen, Regula Laux-End, Anita C. Truttmann, Andreas Schibler, John A. S. McGuigan, Edgar Peheim, Mario G. Bianchetti
Journal:
Clinical Science
Clin Sci (Lond) (1996) 91 (3): 347–351.
Published: 01 September 1996
... of the syndrome of tetany and the cardiac complications that are precipitated by hyperventilation. 30 4 1996 24 5 1996 © 1996 The Biochemical Society and the Medical Research Society 1996 alkalosis calcium hyperventilation magnesium potassium Clinical Science (1996) 91, 347-351...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1995) 88 (6): 695–700.
Published: 01 June 1995
... free [K + ]. 10 2 1995 23 2 1995 © 1995 The Biochemical Society and the Medical Research Society 1995 leucocytes lymphocytes Na + -K + -exchanging ATPase ouabain potassium Clinical Science (1995) 88, 695-700 (Printed in Great Britain) 695 Effect of extracellular potassium...
Articles
Andrea Natali, Alfredo Quiñones Galvan, Donatella Santoro, Neda Pecori, Stefano Taddei, Antonio Salvetti, Eleuterio Ferrannini
Journal:
Clinical Science
Clin Sci (Lond) (1993) 85 (3): 327–335.
Published: 01 September 1993
... nmoll −1 3h, P <0.04) but a blunted hypokalemic response (−7±1 versus −16±1%, P <0.001). Both absolute and fractional urinary excretion of sodium and potassium were significantly decreased during glucose-induced hyperinsulinaemia in hypertensive patients as well as in normotensive subjects ( P...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1993) 84 (4): 401–405.
Published: 01 April 1993
... + -K + pump rate constant during the menstrual cycle. 23 10 1992 25 11 1992 © 1993 The Biochemical Society and the Medical Research Society 1993 adenosine triphosphatase erythrocytes menstrual cycle potassium pregnancy sodium sodium-potassium pump Clinical Science (1993...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1992) 83 (5): 567–574.
Published: 01 November 1992
...Marjolijn van Buren; Ton J. Rabelink; Herman J. M. van Rijn; Hein A. Koomans 1. Potassium salts increase sodium excretion in humans. To define the role of the potassium ion in this effect, we compared the effects of equimolar single oral loads of 100 mmol of NaCl and KCl on renal electrolyte...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1990) 79 (6): 625–630.
Published: 01 December 1990
... to the under- lying sodium pump physiology. Key words: affinity constant, erythrocyte, maximum velocity, potassium, rate constant, sodium, sodium trans- port. Abbreviations: SE, standard error; SEE, standard error of the estimate. Correspondence: Dr T. H. Thomas, Nephrology Research Laboratories, Podium Level...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1990) 79 (5): 499–504.
Published: 01 November 1990
... of provoking more complex and sustained arrhythmias. 4. The effect of pressure changes were highly dependent upon electrolyte concentrations in the perfusate. Low potassium and magnesium concentrations increased the amount of arrhythmia provoked by pressure increases but tended to reduce that provoked...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1990) 78 (3): 255–259.
Published: 01 March 1990
...B. J. Lipworth; D. G. McDevitt; A. D. Struthers 1. Twelve normal subjects were given 5 days' treatment with (a) placebo; (b) 5 mg of bendrofluazide; (c) 5 mg of bendrofluazide plus 24 mmol of potassium; (d) 5 mg of bendrofluazide plus 24 mmol of magnesium; (e) 5 mg of bendrofluazide plus 24 mmol...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1990) 78 (2): 185–191.
Published: 01 February 1990
...L. A. Corr; R. M. Grounds; J. L. Beacham; J. G. Whitwam; M. J. Brown 1. To examine the metabolic effects of increases in circulating endogenous plasma catecholamines, we measured plasma glucose, potassium and magnesium in 14 patients undergoing elective coronary artery bypass grafting. The patients...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1989) 77 (2): 157–160.
Published: 01 August 1989
..., and centrifugation on leucocyte sodium and potassium content. 2. Sodium content fell markedly during the first 30 min after isolation and was stable from 1 to 3 h of incubation. There was a small but significant rise in potassium content over the same time period. 3. During incubation, occasional gentle resuspension...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1988) 74 (6): 595–597.
Published: 01 June 1988
...W. J. W. Bos; D. S. Postma; J. J. van Doormaal 1. The effect of terbutaline infusion over 4 h on serum levels of potassium, ionized calcium, phosphate and magnesium and urinary excretion of potassium, calcium, magnesium and adenosine 3′:5′-cyclic monophosphate was studied in six healthy volunteers...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1988) 74 (4): 397–401.
Published: 01 April 1988
...A. D. Struthers; C. Quigley; M. J. Brown 1. The game of squash has recently been associated with a high incidence of ventricular arrhythmias and sudden death. To investigate this further, plasma catecholamines and potassium (K + ) were monitored during a game of squash in six normal volunteers. 2...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1988) 74 (3): 241–248.
Published: 01 March 1988
... and the Medical Research Society 1970 magnesium muscle biopsies potassium sodium sodium potassium pumps Clinical Science ( 1988) 74,24 1-248 24 1 A simple and rapid method for the determination of the concentrations of magnesium, sodium, potassium and sodium, potassium pumps in human skeletal muscle...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 73 (4): 411–416.
Published: 01 October 1987
... amount after alcohol and the isocaloric glucose control drink, but peak plasma insulin levels were higher after the control drink. 5. Plasma sodium rose in keeping with alcohol induced water diuresis. No significant changes in plasma potassium or magnesium were seen after alcohol. 6. Compared...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 73 (4): 387–393.
Published: 01 October 1987
... and the Medical Research Society 1970 blood cells catecholamines ethanol leucocytes Na + K + -ATPase potassium sodium ...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 73 (3): 259–265.
Published: 01 September 1987
...G. M. Bell; W. Reid; D. J. Ewing; A. D. Cumming; M. L. Watson; A. Doig; B. F. Clarke 1. Diurnal patterns of urine output and sodium and potassium excretion were studied in 10 diabetic patients with and 10 without autonomic neuropathy, and in 10 normal subjects. 2. The diurnal patterns of excretion...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 72 (6): 749–756.
Published: 01 June 1987
... volunteers. 2. Urine volume was increased by 360 mg of caffeine only. At caffeine doses greater than 90 mg urinary sodium excretion was significantly increased. There were no changes in ERPF. 3. Serum potassium was significantly reduced by 360 mg of caffeine. 4. Caffeine increased systolic pressure in a dose...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 72 (5): 577–583.
Published: 01 May 1987
... hyperkalaemia potassium urine electrolytes 10 11 1986 25 11 1986 ClinicalScience( 1987) 72,577-583 577 The relationship between the plasma potassium concentration and renal potassium excretion in the adrenalectomized rat M. L. WEST, H. SONNENBERG, A. VERESS AND M. L. HALPERIN Departments...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 72 (3): 321–327.
Published: 01 March 1987
... to decrease total body Na+. 5. These results confirm previous findings that K+ causes a diuresis and a natriuresis, but demonstrate that the diuretic action of K+ cannot explain its antihypertensive properties in young SHR. Key words: electrolyte balance, hypertension, potassium, sodium, spontaneously...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 72 (3): 313–319.
Published: 01 March 1987
... of action of each appears to be different and may be antagonistic in these animals. Key words: diet, hypertension, plasma renin, potassium, sodium, spontaneously hypertensive rat. Abbreviations: ANG, angiotensin; PRA, plasma renin activity; SHR, spontaneously hypertensive rats. *Present address: Blood...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1987) 72 (2): 171–179.
Published: 01 February 1987
...F. A. Khan; D. N. Baron 1. In hyperthyroidism, erythrocytes show decreased Na + ,K + -ATPase activity, decreased [ 3 H]ouabain binding capacity (an index of the number of sodium pumps) and decreased active sodium and potassium flux rates, with a high intracellular sodium concentration. 2...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1986) 71 (6): 639–646.
Published: 01 December 1986
...T. H. Thomas; C. Mason; K. M. Illingworth 1. Rats were studied 7 days and 17 days after the onset of renal failure which was induced by a surgical technique. 2. Plasma urea, creatinine ( P Cr ) and potassium had increased after 7 days; plasma potassium increased much more after 17 days but P Cr...
Articles
E. Fiaccadori, S. Del Canale, U. Arduini, C. Antonucci, E. Coffrini, P. Vitali, R. Meley, A. Guariglia
Journal:
Clinical Science
Clin Sci (Lond) (1986) 71 (6): 703–712.
Published: 01 December 1986
... subjects. 2. Muscle samples were analysed to obtain intracellular bicarbonate and pH values from total acid-labile carbon dioxide content. Muscle potassium, magnesium and sodium content were also determined, as well as water compartments. 3. Skeletal muscle of COLD patients with ARF showed intracellular...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1986) 71 (4): 445–448.
Published: 01 October 1986
... PEG 200 administration, water consumption in intact rats exceeded urine output. 4. PEG 200 enhanced the excretion of both sodium and potassium, but the sodium excretion was proportionately greater, resulting in an elevation of the urinary sodium/potassium ratio. 5. Bilateral nephrectomy...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1986) 71 (4): 375–383.
Published: 01 October 1986
...William R. Adam 1. By defining a model for control of potassium homoeostasis, patients with unexplained hypokalaemia may then be described as fitting or not fitting the model. Fitting the model implies an abnormality of known control mechanisms (e.g. aldosterone); by contrast, not fitting the model...
Articles
Gordon T. McInnes, Josue G. Flores, John R. Shelton, Ian R. Harrison, Richard M. Perkins, Joan M. Clarke
Journal:
Clinical Science
Clin Sci (Lond) (1986) 71 (1): 125–128.
Published: 01 July 1986
.... Urine was collected from 7 to 15 h (overnight) and 15 to 25 h (daytime) after the start of dietary control. 2. Differences in mean responses were slight. For sodium and potassium excretion, however, there were tendencies for responses in subjects with high excretion on normal diet to decrease...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1986) 70 (6): 611–616.
Published: 01 June 1986
... receiving digoxin and in patients with chronic renal failure are compatible with a widespread reduction in sodium, potassium-ATPase activity in vivo , the findings in patients with untreated essential hypertension are not. 4. Further analysis of the data and a similar study of the disposition of 42 K after...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1986) 70 (4): 347–352.
Published: 01 April 1986
.... No changes in specific airways conductance or maximal expiratory flow rates were seen during the noradrenaline or control infusion. 4. The highest adrenaline infusion rate caused a rise in systolic blood pressure ( P < 0.05) and plasma glucose ( P < 0.05) and a fall in plasma potassium ( P < 0.05...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1985) 69 (3): 293–298.
Published: 01 September 1985
... in distal nephron water permeability. Correspondence: Dr S. Carney, Department of Medicine, Maddison Building, Royal Newcastle Hospital, Newcastle, New South Wales, 2300, Australia. Key words: counter-current mechanism, indo- methacin, potassium, prostaglandins, renal function, sodium, urine concentration...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1985) 68 (5): 517–521.
Published: 01 May 1985
... at concentrations at and above 9 nmol/l increases the influx of rubidium (a model for potassium flux) into cells, with a simultaneous efflux of sodium. There is no effect on Na + , K + -ATPase activity in lysed leucocytes. 3. Use of the adrenoceptor blockers timolol and atenolol shows that the demonstrated effect...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1985) 68 (5): 601–604.
Published: 01 May 1985
... collections. 2. Males had higher urinary excretion of 6-keto-PGF 1α but not of PGE 2 compared with females. 3. Urinary potassium was related to 6-keto-PGF 1α in both 4 and 12 h urine collections and urinary sodium to 6-keto-PGF α in 4 h collections only. 4. In the sexes combined multiple regression analyses...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1984) 67 (4): 427–431.
Published: 01 October 1984
...R. A. F. Linton; M. Lim; C. B. Wolff; P. Wilmshurst; D. M. Band 1. Five continuous records of arterial plasma potassium were obtained from three normal subjects during brief periods (5–7 min) of exercise (100 W). 2. In two of these subjects hepatic venous blood samples were withdrawn at 0.5–1.0 min...
Articles
H. M. James, J. T. Dabek, D. R. Chettle, P. W. Dykes, J. H. Fremlin, J. Hardwicke, B. J. Thomas, D. Vartsky
Journal:
Clinical Science
Clin Sci (Lond) (1984) 67 (1): 73–82.
Published: 01 July 1984
...) is proportional to whole body protein (cellular + extracellular) while whole body potassium (WBK) is almost entirely intracellular. WBK might be an adequate index of cellular wasting. 2. WBN was measured by neutron activation and WBK by counting 40 K in 29 healthy males and 131 male and female patients with wide...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1984) 66 (2): 237–239.
Published: 01 February 1984
... to the elevation of the peripheral resistance. arterioles forearm hypertension potassium sodium pump © 1984 The Biochemical Society and the Medical Research Society 1984 23 8 1983 5 10 1983 Clinical Science (1984) 66, 237-239 SHORT COMMUNICATION 237 The dilator response to K...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1983) 65 (3): 243–245.
Published: 01 September 1983
...Kay Tee Khaw 1. A survey of blood pressure in 93 male London factory workers found a significant correlation between individual systolic blood pressure and sodium/creatinine and sodium/potassium ratios estimated from casual urine samples. 2. Casual urine samples may have value in assessing...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1983) 64 (5): 505–510.
Published: 01 May 1983
...H. Schlebusch; M. Sorger; A. Höck; F. KrüCk 1. in twenty normal subjects and five patients with disturbances of potassium balance, the potassium concentration in leucocytes was measured by a modified technique. 2. The precision of the method was three to four times greater than that of techniques...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1983) 64 (4): 383–386.
Published: 01 April 1983
...-loaded men. 2. Serum insulin reached 96.8 ± 18.1 μ-units/ml (control: 7.0 ± 1.5 μ-units/ml) and serum potassium fell from 4.2 ± 0.2 mmol/l to 3.6 ± 0.2 mmol/l ( P < 0.005). 3. Hyperinsulinaemia increased ( P < 0.05) the secretion of aldosterone during the largest dose of angiotensin II (20 ng min...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1983) 64 (2): 167–176.
Published: 01 February 1983
...M. Cumberbatch; D. B. Morgan 1. The erythrocyte content of sodium and of potassium were measured in 231 unselected patients with hypokalaemia, and together with net ouabain-sensitive sodium efflux in patients with severe hypokalaemia, before (20 patients) and during potassium repletion (14 patients...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (s8): 97s–100s.
Published: 01 October 1982
..., normokalaemia was found in 27.5% of patients; 12.5% remained so despite 3 days of salt loading. Suppressed plasma renin activity (PRA: less than 1.43 pmol/l after stimulated conditions) gave a false-negative rate of 36%. Thus sole reliance on either hypokalaemia (serum potassium less than 3.5 mmol/l...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (s8): 27s–29s.
Published: 01 October 1982
... noradrenaline release from synaptosomes in response to a low potassium ion concentration and the incorporation of noradrenaline into synaptosomes were significantly increased in 3-month-old SHRSP compared with WKY rats. 3. Cultured smooth muscle cells obtained from the aorta of SHRSP showed a greater Na...
Articles
The Effect of Potassium and Bicarbonate Ions on the Rise in Blood Pressure Caused by Sodium Chloride
Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (s8): 407s–409s.
Published: 01 October 1982
... chloride given together with potassium chloride (70 mmol of each daily) caused their blood pressure to rise by 9.6 mmHg. 5. These results suggest that sodium bicarbonate causes a smaller rise in blood pressure than sodium chloride does and that potassium chloride reduces the blood pressure raising effect...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (s8): 83s–85s.
Published: 01 October 1982
... and the Medical Research Society 1982 artery strips calcium diltiazem noradrenaline potassium smooth muscle Clinical Science (1982) 63,83~-85s 83s Calcium-induced contraction and effect of calcium antagonist on arterial smooth muscle of spontaneously hypertensive rats Y O S H I N O R 1 K A W A G U C...
Articles
C. Beretta-Piccoli, D. L. Davies, J. J. Brown, J. B. Ferriss, R. Fraser, A. F. Lever, J. J. Morton, J. I. S. Robertson
Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (s8): 89s–92s.
Published: 01 October 1982
...C. Beretta-Piccoli; D. L. Davies; J. J. Brown; J. B. Ferriss; R. Fraser; A. F. Lever; J. J. Morton; J. I. S. Robertson 1. Arterial pressure, exchangeable sodium (Na E ), exchangeable potassium (K E ) and plasma concentrations of sodium, potassium, urea, angiotension II and aldosterone were measured...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (s8): 129s–132s.
Published: 01 October 1982
... as dual-mechanism diuretic agents with K + sparing properties and thus act as a novel class of antihypertensive drugs. © 1982 The Biochemical Society and the Medical Research Society 1982 aldosterone hydrochlorothiazide potassium riboflavin analogues salt-sensitive hypertension sodium balance...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (s8): 231s–234s.
Published: 01 October 1982
...E. Ambrosioni; F. V. Costa; C. Borghi; L. Montebugnoli; M. F. Giordani; L. Vasconi 1. Twenty young subjects with borderline hypertension were studied to evaluate the effects of moderate salt restriction and/or of a high potassium intake on intralymphocytic sodium content and blood pressure. Blood...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1982) 62 (4): 373–380.
Published: 01 April 1982
...M. G. Nicholls; M. Tree; J. H. Livesey; R. Fraser; J. J. Morton; J. I. S. Robertson 1. Potassium was infused intravenously in an incremental fashion and the plasma aldosterone responses were measured in conscious beagle dogs at five different intakes of dietary sodium. 2. Potassium/aldosterone dose...
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