... The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2018 hypertension diet-induced obesity potassium channels small arteries vascular tone In the present study, we therefore decided to evaluate outbred Sprague–Dawley (SD) rats exposed to a diet rich...

... of the cAMP-mediated relaxation in CA under HG. This protective effect was associated with induction of PDK4, attenuation of oxidative stress and preservation of Kv7 channel function. cAMP coronary circulation diabetes mellitus potassium channels PPARβ/δ 1 Both authors contributed...

...C. A. HAMILTON; G. BERG; K. MCARTHUR; J. L. REID; A.F. DOMINICZAK Opening of potassium channels can cause hyperpolarization and relaxation of vascular smooth muscle cells. The aim of this work was to investigate the contribution of potassium channel activation to vasorelaxation in internal thoracic...

... acetylcholine-induced relaxation. Tolbutamide at 2 mmol/l or 10 μmol/l glyburide (blockers of ATP-sensitive potassium channels) partially inhibited N G -nitro-l-arginine methyl ester-resistant endothelium-dependent relaxation. Apamin (a blocker of small-conductance calcium-activated potassium channels), which...

...T. P. Links; A. J. Smit; H. J. G. H. Oosterhuis; W. D. Reitsma 1. A possible role for the ATP-sensitive potassium channels in the pathogenesis of hypokalaemic periodic paralysis was investigated. 2. We assessed insulin release and muscle strength after intravenous glucose loading with and without...