... in an HDM (house dust mite) mouse model of asthma and assess the effect of oral corticosteroids. HDM alone significantly increased eosinophils, lymphocytes, neutrophils, macrophages and a number of cytokines in BAL (bronchoalveolar lavage), all of which were sensitive to treatment with prednisolone...

... glucocorticoids 11β-hydroxysteroid dehydrogenase osteoblasts osteoporosis prednisolone The adverse effects of glucocorticoids on the skeleton were first recognized by Harvey Cushing [ 1 ] 70 years ago in the context of the disease that bears his name. However, the problem of GIOP (glucocorticoid...

... of protein) was increased in the DOCA-treated (33.0 ± 6.9) and in the prednisolone-treated groups (30.8 ± 6.9) compared with that in the control group (26.4 ± 3.4) ( P < 0.05). In the liver, the ouabain-sensitive Na + ,K + -ATPase activity was elevated in the prednisolone-treated animals only (4.8 ± 1.3...

...S. H. D. Jackson; D. G. Beevers; K. Myers 1. One hundred and ninety-five patients undergoing low-dose prednisone or prednisolone therapy were investigated. Blood pressure, weight, serum urea, sodium and potassium were recorded before therapy and again after at least 1 year of therapy. 2. The rise...

...R. M. Batt; T. J. Peters 1. The effects in rats of an oral pharmacological dose of prednisolone on mucosal function, enzymology, lysosomal membrane fragility, morphology and cell kinetics have been examined in proximal jejunum and distal ileum. 2. The maximum absorptive capacity for galactose...