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Keyword: preeclampsia
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Articles
Clin Sci (Lond) (2020) CS20191253.
Published: 21 January 2020
...Yanling Chang; Yunyan Chen; Qiong Zhou; Chuan Wang; Lei Chen; Wen Di; Yu Zhang Preeclampsia (PE) is regarded as a pregnancy-associated hypertension disorder that is related to excessive inflammatory responses. Although the gut microbiota (GM) and short-chain fatty acids (SCFA) have been related to...
Articles
Clin Sci (Lond) (2020) 134 (2): 87–101.
Published: 21 January 2020
...Kenny Schlosser; Amanpreet Kaur; Natalie Dayan; Duncan J. Stewart; Louise Pilote; Christian Delles; Christian Delles Women with a history of preeclampsia (PE) have increased risk of cardiovascular disease (CVD) later in life. However, the molecular determinants underlying this risk remain unclear...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2019) 133 (12): 1341–1352.
Published: 20 June 2019
...Emilie Hitzerd; Rugina I. Neuman; Katrina M. Mirabito Colafella; Irwin K.M. Reiss; Anton H. van den Meiracker; A.H. Jan Danser; Willy Visser; Jorie Versmissen; Langeza Saleh Preeclampsia (PE) is a pregnancy complication, featuring elevated blood pressure and proteinuria, with no appropriate...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2018) 132 (12): 1215–1242.
Published: 21 June 2018
..., most prominent being marinobufagenin (MBG). A synthetic pathway for MBG has been identified in mammalian placental tissue. Elevated maternal and fetal EDLF, O and MBG have been demonstrated in preeclampsia (PE), and inhibition of red cell membrane sodium, potassium ATPase (Na, K ATPase (NKA)) by EDLF...
Articles
Clin Sci (Lond) (2018) 132 (3): 419–436.
Published: 14 February 2018
...Sabrina M. Scroggins; Donna A. Santillan; Jenna M. Lund; Jeremy A. Sandgren; Lindsay K. Krotz; Wendy S. Hamilton; Eric J. Devor; Heather A. Davis; Gary L. Pierce; Katherine N. Gibson-Corley; Curt D. Sigmund; Justin L. Grobe; Mark K. Santillan The pathogenesis of preeclampsia (PreE), a hypertensive...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2018) 132 (1): 33–36.
Published: 02 January 2018
... preeclampsia Pre-eclampsia, defined as de novo hypertension after 20 weeks’ gestation and albuminuria, maternal organ dysfunction (renal insufficiency, hemolysis, elevated liver enzymes, low platelet count (HELLP) syndrome, or neurological complications) and/or fetal growth restriction, is associated...
Articles
Clin Sci (Lond) (2017) 131 (24): 2911–2917.
Published: 08 December 2017
... preeclampsia pregnancy T lymphocytes Pre-eclampsia (PE) is a highly variable and heterogeneous syndrome that is defined by new-onset hypertension after 20 weeks of gestation and one or more of the following diagnostic criteria: new-onset proteinuria, thrombocytopenia, impaired liver function, renal...
Articles
Clin Sci (Lond) (2017) 131 (23): 2777–2789.
Published: 23 November 2017
... postpartum women who had preeclampsia (PrEC, n =12) and control women who had a healthy pregnancy (HC, n =12). We hypothesized that (1) PrEC would have a greater vasoconstrictor response to ET-1, and (2) reduced ET B R-mediated dilation. We further hypothesized that ET B R-blockade would attenuate...
Articles
Clin Sci (Lond) (2017) 131 (23): 2753–2762.
Published: 23 November 2017
...Jamil Elfarra; Lorena M. Amaral; Maggie McCalmon; Jeremy D. Scott; Mark W. Cunningham, Jr; Ashley Gnam; Tarek Ibrahim; Babbette LaMarca; Denise C. Cornelius Preeclampsia is associated with hypertension, small-for-gestational-age babies, and increased cytolytic natural killer (NK) cells. The...
Articles
Clin Sci (Lond) (2017) 131 (15): 2047–2058.
Published: 17 July 2017
... pregnancy can lead to organ injury and dysfunction and preeclampsia (PE); however, the molecular mechanisms involved are unknown. We tested the hypothesis that Toll-like receptor (TLR) activation induces major histocompatibility complex (MHC) class II invariant chain peptide (CLIP) expression on immune...
Articles
Clin Sci (Lond) (2017) 131 (13): 1529–1540.
Published: 28 June 2017
... published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . adipocytes adipokines pregnancy preeclampsia Pre-eclampsia (PE) occurs in 2–4% of all pregnancies and is a leading cause of maternal and...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2016) 130 (16): 1417–1434.
Published: 07 July 2016
...Omar C. Logue; Eric M. George; Gene L. Bidwell, III Preeclampsia (PE) is a form of gestational hypertension that complicates ∼5% of pregnancies worldwide. Over 70% of the fatal cases of PE are attributed to cerebral oedema, intracranial haemorrhage and eclampsia. The aetiology of PE originates from...
Articles
Clin Sci (Lond) (2016) 130 (4): 239–246.
Published: 14 January 2016
...Nina D. Paauw; Kim Luijken; Arie Franx; Marianne C. Verhaar; A. Titia Lely Preeclampsia (PE) is a hypertensive pregnancy disorder complicating up to 1–5% of pregnancies, and a major cause of maternal and fetal morbidity and mortality. In recent years, observational studies have consistently shown...
Articles
Clin Sci (Lond) (1985) 69 (4): 477–482.
Published: 01 October 1985
...-eclampsia, 10 normotensive pregnant women and eight normotensive nonpregnant women were determined. 2. In vessels from the women with preeclampsia, the ratio of media thickness to lumen diameter was increased, compared with that in vessels from the other two groups. 3. The vessels from the women with...