...Jeremy M. Palmer; Margaret F. Bassendine; Oliver F. W. James; Stephen J. Yeaman 1. The sera of more than 90% of patients with primary biliary cirrhosis contain antimitochondrial antibodies which react with the E2 component of the pyruvate dehydrogenase complex, identified as the major autoantigen...

...Shelley P. M. Fussey; Shauna M. West; J. Gordon Lindsay; C. Ian Ragan; Oliver F. W. James; Margaret F. Bassendine; Stephen J. Yeaman 1. In primary biliary cirrhosis, the major M2 autoantigen, reacting with antimitochondrial antibodies in sera from >90% of patients, has been identified as the E2...

...Shelley P. M. Fussey; Margaret F. Bassendine; Dorothy Fittes; Ian B. Turner; Oliver F. W. James; Stephen J. Yeaman 1. Sera from 76 patients with primary biliary cirrhosis (PBC) and 66 control subjects (53 with chronic liver disease and 13 healthy normal women) were immunoblotted against purified E1...

...E. Barbara Mawer; H. J. Klass; T. W. Warnes; Jacqueline L. Berry 1. The metabolism of isotopically labelled vitamin D 2 and D 3 has been investigated in eight patients with primary biliary cirrhosis and in five controls. The concentration of labelled vitamin D 2 was lower than that of vitamin D 3...

...I. G. McFarlane; B. M. McFarlane; A. J. Haines; A. L. W. F. Eddleston; Roger Williams 1. According to a recent hypothesis, based on similarities between chronic graft versus host disease and primary biliary cirrhosis (PBC), immune reactions against histocompatibility (HLA) antigens-6-be responsible...