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Keywords: prognosis
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Clin Sci (Lond) (2021) 135 (7): 847–864.
Published: 06 April 2021
... of the core components of cytoskeleton, in this process is only beginning to be revealed. Here, we find that the MT dynamics regulator end-binding protein 2 (EB2) is highly expressed in HCC and predicts poor prognosis of HCC patients. Functional studies show that EB2 overexpression promotes HCC proliferation...
Includes: Supplementary data
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Clin Sci (Lond) (2020) 134 (7): 711–726.
Published: 03 April 2020
... by Portland Press Limited on behalf of the Biochemical Society 2020 PD-1 prognosis T cell exhaustion triple-negative breast cancer Breast cancer (BC) is the most commonly occurring cancer in women worldwide, estimated over 2 million new cases in 2018 [ 1 ]. Classically, BC can be categorized...
Includes: Supplementary data
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Clin Sci (Lond) (2016) 130 (11): 921–930.
Published: 29 April 2016
... on the expression, function and mechanisms of miR-92b in osteosarcoma development. The miRNA miR-92b was up-regulated in osteosarcoma cell lines and tissues; miR-92b up-regulation correlated with poor prognosis in osteosarcoma. Overexpression of miR-92b promoted osteosarcoma cell proliferation, migration...
Includes: Supplementary data
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Clin Sci (Lond) (2015) 128 (10): 619–634.
Published: 20 February 2015
[email protected] ) 29 8 2014 24 11 2014 9 12 2014 © The Authors Journal compilation © 2015 Biochemical Society 2015 diagnosis individualized treatment miRNA non-small-cell lung cancer (NSCLC) post-transcriptional regulation prognosis Lung cancer remains the leading...
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Clin Sci (Lond) (2014) 127 (4): 233–242.
Published: 10 April 2014
... (zero time). breast carcinoma microRNA neoplasm metastasis and recurrence prognosis Scribble A second administration of miRNA molecules was performed after 7 days and mice were killed at day 14. Tumour size was measured every other day. To normalize the tumour volume data, each daily...
Includes: Supplementary data
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Clin Sci (Lond) (2014) 126 (5): 339–346.
Published: 25 October 2013
... 25-hydroxyvitamin D [25(OH)D] prognosis stroke • Low vitamin D levels have been reported to contribute to the risk of cardiovascular events and mortality, especially stroke. • In the present study, we found that that 25(OH)D is an independent prognostic marker for death...
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Clin Sci (Lond) (2013) 124 (3): 203–214.
Published: 17 October 2012
... that induction of autophagy promotes VPRBP–LC3/p62 interaction. Immunohistochemical examination of human NSCLC (non-small cell lung cancer) tissues showed that VPRBP was positively correlated with p62 and negatively correlated with LC3B. Moreover, p62 and VPRBP were associated with poor prognosis in lung ADC...
Includes: Supplementary data
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Clin Sci (Lond) (2011) 121 (10): 437–447.
Published: 25 July 2011
... an ROC (receiver operating characteristic) AUC (area under the curve) of 0.902 [95% CI (confidence interval), 0.857–0.936] in the discovery group and a similar result in the validation group [ROC AUC, 0.888 (95% CI, 0.819–0.939)]. Patients with high-levels of serum miR-31 also had a poorer prognosis...
Includes: Supplementary data
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Clin Sci (Lond) (2011) 120 (6): 231–238.
Published: 03 December 2010
... PR3 in determining mortality and incidence of heart failure following AMI, independent of established conventional risk factors. PR3 may represent a clinically useful marker of prognosis after an AMI as part of a multimarker strategy. Correspondence: Professor Leong L. Ng (email [email protected]...
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Clin Sci (Lond) (2010) 119 (5): 203–205.
Published: 02 June 2010
... be useful to delineate the disease severity and prognosis, as well as to monitor the clinical course and response to therapy [ 7 ]. The results reported by Filusch et al. [ 7 ] indicate that hsTnT may soon become part of the standard work-up and follow-up of PAH patients. Any improvement...
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Clin Sci (Lond) (2010) 118 (4): 249–257.
Published: 09 November 2009
... to be statistically significant. acute coronary syndrome matrix metalloproteinase (MMP) myocardial infarction N-terminal B-type natriuretic peptide (NT-proBNP) prognosis MMPs (matrix metalloproteinases) are a family of zinc-containing endoproteinases which, along with their inhibitors [TIMPs...
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Clin Sci (Lond) (2009) 117 (1): 13–15.
Published: 02 June 2009
...-terminal pro-B-type natriuretic peptide (NT-proBNP) prognosis In the present issue of Clinical Science , Khan et al. [ 1 ] have compared the prognostic value of the GRACE (Global Registry of Acute Coronary Events) risk score, the cardiac biomarker NT-proBNP (N-terminal pro-B-type natriuretic peptide...
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Clin Sci (Lond) (2005) 108 (1): 23–36.
Published: 15 December 2004
..., is increasing in both incidence and prevalence. Although the survival rate of patients diagnosed with HF has improved over the past decade due to advances in anti-HF therapy, the prognosis remains poor [ 8 ]. On this background and in light of evidence from clinical trials demonstrating marked benefits...
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Clin Sci Mol Med (1973) 45 (s1): 311s–314s.
Published: 01 August 1973
... The Biochemical Society and the Medical Research Society 1994 hypertension renal artery stenosis renal parenchyma renin activity renal veins prognosis Clinical Science and Molecular Medicine (1973) 45, 31 1s-314s. DIVIDED RENAL A N D PERIPHERAL VENOUS RENIN AS A MEANS OF PREDICTING OPERATIVE...