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Keywords: prognosis
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Articles
Clin Sci (Lond) (2021) 135 (7): 847–864.
Published: 06 April 2021
... of the core components of cytoskeleton, in this process is only beginning to be revealed. Here, we find that the MT dynamics regulator end-binding protein 2 (EB2) is highly expressed in HCC and predicts poor prognosis of HCC patients. Functional studies show that EB2 overexpression promotes HCC proliferation...
Includes: Supplementary data
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Clin Sci (Lond) (2020) 134 (7): 711–726.
Published: 03 April 2020
... by Portland Press Limited on behalf of the Biochemical Society 2020 PD-1 prognosis T cell exhaustion triple-negative breast cancer Breast cancer (BC) is the most commonly occurring cancer in women worldwide, estimated over 2 million new cases in 2018 [ 1 ]. Classically, BC can be categorized...
Includes: Supplementary data
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Clin Sci (Lond) (2016) 130 (11): 921–930.
Published: 29 April 2016
... on the expression, function and mechanisms of miR-92b in osteosarcoma development. The miRNA miR-92b was up-regulated in osteosarcoma cell lines and tissues; miR-92b up-regulation correlated with poor prognosis in osteosarcoma. Overexpression of miR-92b promoted osteosarcoma cell proliferation, migration...
Includes: Supplementary data
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Clin Sci (Lond) (2015) 128 (10): 619–634.
Published: 20 February 2015
... treatment miRNA non-small-cell lung cancer (NSCLC) post-transcriptional regulation prognosis Lung cancer remains the leading cause of cancer-related death worldwide. Non-small-cell lung cancer (NSCLC) accounts for approximately 80–85% of cases, with squamous cell carcinoma (SCC...
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Clin Sci (Lond) (2014) 126 (5): 339–346.
Published: 25 October 2013
... 25-hydroxyvitamin D [25(OH)D] prognosis stroke • Low vitamin D levels have been reported to contribute to the risk of cardiovascular events and mortality, especially stroke. • In the present study, we found that that 25(OH)D is an independent prognostic marker for death...
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Clin Sci (Lond) (2013) 124 (3): 203–214.
Published: 17 October 2012
... that induction of autophagy promotes VPRBP–LC3/p62 interaction. Immunohistochemical examination of human NSCLC (non-small cell lung cancer) tissues showed that VPRBP was positively correlated with p62 and negatively correlated with LC3B. Moreover, p62 and VPRBP were associated with poor prognosis in lung ADC...
Includes: Supplementary data
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Clin Sci (Lond) (2012) 123 (9): 557–566.
Published: 13 July 2012
...-binding protein (LTBP) prognosis pulmonary death Acute dyspnoea is one of the most common chief complaints of patients presenting to the emergency department [ 1 ], with the array of possible underlying pathologies ranging from anxiety and hyperventilation to life-threatening pulmonary, cardiac...
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Clin Sci (Lond) (2011) 121 (10): 437–447.
Published: 25 July 2011
... an ROC (receiver operating characteristic) AUC (area under the curve) of 0.902 [95% CI (confidence interval), 0.857–0.936] in the discovery group and a similar result in the validation group [ROC AUC, 0.888 (95% CI, 0.819–0.939)]. Patients with high-levels of serum miR-31 also had a poorer prognosis...
Includes: Supplementary data
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Clin Sci (Lond) (2011) 120 (6): 231–238.
Published: 03 December 2010
... PR3 in determining mortality and incidence of heart failure following AMI, independent of established conventional risk factors. PR3 may represent a clinically useful marker of prognosis after an AMI as part of a multimarker strategy. Blood samples were drawn at 2–5 days after the onset of chest...
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Clin Sci (Lond) (2010) 119 (5): 203–205.
Published: 02 June 2010
... be helpful not only in risk assessment, but also in the selection of treatment modalities and care intensity. Moreover, reliable indicators of clinical worsening and disease severity may be useful to delineate the disease severity and prognosis, as well as to monitor the clinical course and response...
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Clin Sci (Lond) (2010) 118 (4): 249–257.
Published: 09 November 2009
...) prognosis MMPs (matrix metalloproteinases) are a family of zinc-containing endoproteinases which, along with their inhibitors [TIMPs (tissue inhibitors of metalloproteinases)] are vital in ensuring a balanced turnover of the cardiac ECM (extracellular matrix). MMPs have been classified into four...
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Clin Sci (Lond) (2009) 117 (1): 13–15.
Published: 02 June 2009
... Coronary Events (GRACE) score myocardial infarction N-terminal pro-B-type natriuretic peptide (NT-proBNP) prognosis Alternatively, improvement in risk classification can be evaluated by the use of event-specific re-classification tables. Predicted probabilities for the outcome in question can...
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Clin Sci (Lond) (2005) 108 (1): 23–36.
Published: 15 December 2004
... peptide diagnosis heart failure prognosis management treatment The cardiac natriuretic peptides, ANP and BNP (atrial and brain natriuretic peptides respectively), are hormones secreted predominantly by the heart. ANP is synthesized most abundantly in the atria where it is stored in specific...
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Clin Sci Mol Med (1973) 45 (s1): 311s–314s.
Published: 01 August 1973
... The Biochemical Society and the Medical Research Society 1994 hypertension renal artery stenosis renal parenchyma renin activity renal veins prognosis Clinical Science and Molecular Medicine (1973) 45, 31 1s-314s. DIVIDED RENAL A N D PERIPHERAL VENOUS RENIN AS A MEANS OF PREDICTING OPERATIVE...