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Keywords: proinsulin
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Clin Sci (Lond) (2009) 116 (7): 565–574.
Published: 02 March 2009
...Claire E. Hills; Nigel J. Brunskill In recent years, accumulating evidence indicates a biological function for proinsulin C-peptide. These results challenge the traditional view that C-peptide is essentially inert and only useful as a surrogate marker of insulin release. Accordingly, it is now...
Clin Sci (Lond) (1995) 89 (3): 321–328.
Published: 01 September 1995
... of growth replacement lasting for 6 months. Biosynthetic human growth hormone was given subcutaneously in a daily dose of 0.02–0.05 i.u./kg at bed time. Fasting insulin, intact proinsulin and 32–33 split proinsulin were measured by two-site immunoradiometric assays. 2. Hypopituitary patients were aged 19–67...
Clin Sci (Lond) (1993) 85 (1): 97–100.
Published: 01 July 1993
... ( P >0.1) for the group with impaired glucose tolerance and the healthy control group, respectively. 3. There was no significant difference ( P >0.1) in fasting plasma insulin or C-peptide concentrations between the groups. 4. By contrast, the fasting concentration of intact proinsulin...