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Keywords: propranolol
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Articles
Propranolol modulates the collateral vascular responsiveness to vasopressin via a G α -mediated pathway in portal hypertensive rats
Available to PurchaseJing-Yi Lee, Teh-Ia Huo, Hui-Chun Huang, Fa-Yauh Lee, Han-Chieh Lin, Chiao-Lin Chuang, Ching-Chih Chang, Sun-Sang Wang, Shou-Dong Lee
Journal:
Clinical Science
Clin Sci (Lond) (2011) 121 (12): 545–554.
Published: 22 August 2011
..., sympathetic tone abnormality and vascular hyporesponsiveness in portal hypertension may impede the haemostatic effects of vasoconstrictors. Propranolol, a β-blocker binding the G-protein-coupled adrenoceptor, is a portal hypotensive agent. However, whether propranolol influences the collateral vasoresponse...
Articles
Influences of propranolol and atenolol on the circadian rhythm of heart rate in elderly patients with essential hypertension
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Journal:
Clinical Science
Clin Sci (Lond) (1990) 78 (4): 403–407.
Published: 01 April 1990
...Hiroyuki Shimamoto; Yoriko Shimamoto; Shogo Sakata 1. The influence of long-acting propranolol and of atenolol on the circadian rhythm of heart rate was assessed using 24 h electrocardiographic recordings in elderly patients with essential hypertension. Eighteen elderly patients were investigated...
Articles
Changes in calcium metabolic indices during long-term treatment of patients with essential hypertension
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Journal:
Clinical Science
Clin Sci (Lond) (1988) 75 (5): 543–549.
Published: 01 November 1988
... secondary to the elevated blood pressure. 2. Indices of systemic calcium metabolism were followed prospectively during 6 months' treatment with either propranolol, bendroflumethiazide or verapamil in 35 patients with essential hypertension. Multivariate statistical methods were employed to study the effects...
Articles
The influence of pregnancy on drug action: Concentration–effect modelling with propranolol
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Journal:
Clinical Science
Clin Sci (Lond) (1987) 73 (1): 47–52.
Published: 01 July 1987
...–effect analysis to determine whether pregnancy influences the action of propranolol. 2. Twelve women with pregnancy induced hypertension were studied during the third trimester and again 2–3 months post partum. On each occasion propranolol (10 mg) was given intravenously and measurements of heart rate...
Articles
The effects of four β -adrenoceptor antagonists during modest exercise on plasma ammonia and heart rate
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Journal:
Clinical Science
Clin Sci (Lond) (1987) 72 (6): 679–682.
Published: 01 June 1987
...P. E. Hall; S. R. Smith; M. J. Kendall 1. Plasma ammonia and heart rate were measured in normal volunteers before, during and after an exercise test following administration of placebo, propranolol, pindolol, metoprolol and nadolol. 2. Small changes in plasma ammonia occurred during exercise after...
Articles
β-Adrenoceptor blockade and plasma lipoproteins. Comparison of the effects of propranolol and pindolol on plasma lipoproteins including high-density lipoprotein subfractions
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Journal:
Clinical Science
Clin Sci (Lond) (1987) 72 (5): 549–556.
Published: 01 May 1987
... lipoproteins during chronic β-adrenoceptor blockade in patients with stable angina pectoris treated with propranolol (without ISA) (n = 21) or pindolol (with ISA) ( n = 19). 2. No significant changes occurred in the lipoprotein profile of the patients taking pindolol. In those taking propranolol, very low...
Articles
Autonomic nervous control of the heart rate during dynamic exercise in normal man
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Journal:
Clinical Science
Clin Sci (Lond) (1986) 71 (4): 457–460.
Published: 01 October 1986
.... The dynamic exercise was performed on a bicycle ergometer at work loads of 25, 50 and 100 W, before and after pharmacological blockade with atropine (13 individuals) or propranolol (10 individuals). 3. Parasympathetic blockade significantly depressed the rapid HR response at the beginning of the exercise...
Articles
Arterial Plasma Potassium Measured Continuously during Exercise in Man
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Journal:
Clinical Science
Clin Sci (Lond) (1984) 67 (4): 427–431.
Published: 01 October 1984
... intervals and analysed in vitro for plasma potassium. 3. Arterial plasma potassium rose rapidly at the start of exercise from 3.8 ± 0.3 mmol/l (mean ± sd) to plateau levels of 5.4 ± 0.1 mmol/l. 4. One of the above subjects and a further subject were studied after β-blockade with propranolol. This resulted...
Articles
Comparison between short-term Renal Haemodynamic Effects of Propranolol and Nadolol in Essential Hypertension: A Crossover Study
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Journal:
Clinical Science
Clin Sci (Lond) (1984) 67 (2): 243–248.
Published: 01 August 1984
...Boothur J. Z. Danesh; Joyce Brunton; David J. Sumner 1. The effect of 4-6 weeks’ treatment with propranolol and nadolol on effective renal plasma flow (ERPF) and glomerular filtration rate (GFR) was studied, in 14 patients with essential hypertension, in single blind, random and cross-over design...
Articles
Effect of Adrenergic and Vagal Blockade on the Normal Human Airway Response to Exercise
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Journal:
Clinical Science
Clin Sci (Lond) (1984) 66 (1): 79–85.
Published: 01 January 1984
...J. B. Warren; S. J. Jennings; T. J. H. Clark 1. Ten normal, non-asthmatic subjects performed an 18 min graduated exercise test on a static exercise bicycle on 3 separate days. They received either no medication, or propranolol 80 mg orally 2 h before, or ipratropium bromide 0.216 mg by inhalation...
Articles
Hypoxia-Induced Cardiovascular Changes and Plasma Electrolytes before and after β -Adrenoceptor Blockade
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Journal:
Clinical Science
Clin Sci (Lond) (1983) 65 (5): 463–468.
Published: 01 November 1983
...Yoseph Assen Mengesha; Ambachew Woreta; Belay Tesfa Mariam 1. The forearm blood flow responses to hypoxia obtained from ten subjects (ages 26–37 years) before and after propranolol showed no relation with either plasma osmolality or plasma concentrations of K + , Na + , Ca 2+ , P i and Cl...
Articles
Effects of Hydralazine versus Propranolol on Blood Velocity Patterns in Patients with Carotid Stenosis
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Journal:
Clinical Science
Clin Sci (Lond) (1983) 65 (1): 91–93.
Published: 01 July 1983
..., and propranolol, 2–5 mg, over 10–15 min each, with return to baseline between drugs. 3. After hydralazine, the occurrence of abnormal high velocity flow patterns increased in 17 of 20 patients; there was no change in three patients. Propranolol reduced the occurrence of abnormal high velocity flow patterns in 19...
Articles
Altered Jejunal Surface pH in Coeliac Disease: Its Effect on Propranolol and Folic Acid Absorption
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Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (4): 373–380.
Published: 01 October 1982
...G. Kitis; M. L. Lucas; H. Bishop; A. Sargent; R. E. Schneider; J. A. Blair; R. N. Allan 1. Propranolol and folic acid absorption were studied separately in healthy subjects, non-coeliac patients and patients with treated and untreated coeliac disease. 2. The surface pH of jejunal biopsy samples...
Articles
Interaction of Metoprolol, Propranolol and Atenolol with Cimetidine
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Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (s8): 451s–453s.
Published: 01 October 1982
...W. Kirch; H. Spahn; H. Köhler; E. Mutschler 1. Pharmacokinetics of metoprolol, propranolol and atenolol were investigated in six healthy volunteers after 7 days of oral monotherapy with these drugs and after 7 days concurrent administration, with each of these β-adrenoceptor antagonists...
Articles
Effect of Long-Term, Once-Daily Administration of Atenolol, Metoprolol, Pindolol and Slow-Release Propranolol on Ambulatory Blood Pressure and its Variability
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Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (s8): 459s–460s.
Published: 01 October 1982
..., pindolol or slow-release propranolol. 3. Drugs were administered in a once-daily variable dose regimen for a period of 3–8 months (mean 5.0 ± sd 1.4). 4. All four drugs reduced blood pressure significantly 24 h after the last dose but there were considerable differences in control when each intervening...
Articles
The Effect of Propranolol or Metoprolol on Thermoregulation during Insulin-Induced Hypoglycaemia in Man
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Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (3): 301–310.
Published: 01 September 1982
...I. A. Macdonald; T. Bennett; E. A. M. Gale; J. Hilary Green; S. Walford 1. The effects of metoprolol and propranolol on heat production and body temperature have been studied in six male subjects during insulin-induced hypoglycaemia in a thermoneutral environment. Hypoglycaemia was induced...
Articles
Effect of Propranolol on Hepatic Blood Flow in Normal and Portal Hypertensive Rats
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Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (1): 29–32.
Published: 01 July 1982
...P. Hillon; L. Blanchet; D. Lebrec 1. The effects of propranolol on heart rate, arterial pressure, portal venous pressure and fractional hepatic blood flow were studied in rats with hepatic artery ligature or with portal vein stenosis, and in sham-operated rats. The effect of propranolol on cardiac...
Articles
Propranolol Absorption in Untreated Coeliac Disease
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Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (1): 81–85.
Published: 01 July 1982
...G. I. Sandle; A. Ward; M. D. Rawlins; C. O. Record 1. To compare the bioavailability and the elimination of propranolol in seven untreated coeliac patients and six normal subjects, plasma concentrations were measured after oral and intravenous propranolol. The bioavailability and clearance...
Articles
The Autonomic Nervous Tone Abnormalities in the Genesis of the Impaired Baroreflex Responsiveness in Borderline Hypertensive Subjects
Available to PurchaseMassimo Volpe, Bruno Trimarcoy, Bruno Ricciardelli, Carlo Vigorito, Nicola De Luca, Franco Rengo, Mario Condorelli
Journal:
Clinical Science
Clin Sci (Lond) (1982) 62 (6): 581–588.
Published: 01 June 1982
...Massimo Volpe; Bruno Trimarcoy; Bruno Ricciardelli; Carlo Vigorito; Nicola De Luca; Franco Rengo; Mario Condorelli 1. The effects of intravenous administration of neostigmine and propranolol, individually or in combination, on baroreflex responsiveness have been evaluated in 18 borderline...
Articles
β -Receptor-Blocking Agents May Reverse or Prevent Diuretic-Induced Increases in Serum Low-Density Lipoprotein Cholesterol
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Journal:
Clinical Science
Clin Sci (Lond) (1981) 61 (s7): 437s–439s.
Published: 01 December 1981
... Society 1981 chlorthalidone clopamide diuretics lipoproteins pindolol propranolol β-receptor blockade Clinical Science (1981) 61,437~439s 437s P-Receptor-blocking agents may reverse or prevent diuretic-induced increases in serum low-density lipoprotein cholesterol A. M E I E R , H . S C H I...
Articles
The Hypotensive Effect of Propranolol in Captopril-Treated Patients Does Not Involve the Plasma Renin—Angiotensin—Aldosterone System
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Journal:
Clinical Science
Clin Sci (Lond) (1981) 61 (s7): 441s–444s.
Published: 01 December 1981
...J. Staessen; R. Fagard; P. Lijnen; L. J. Verschueren; A. Amery 1. With a double-blind cross-over protocol, 20 hypertensive captopril-treated patients were studied by adding in a variable sequence a placebo and propranolol (80 mg three times a day) to their captopril regimen (200 mg three times...
Articles
Decrease in α-Adrenoceptor-Mediated Vasoconstriction Parallels the Antihypertensive Response to Propranolol in Patients with Normal Renin Essential Hypertension
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Journal:
Clinical Science
Clin Sci (Lond) (1981) 61 (s7): 445s–448s.
Published: 01 December 1981
...F. W. Amann; P. Bolli; L. Hulthén; W. Kiowski; F. R. Bühler 1. α 1 -Adrenoceptor-mediated vasoconstriction was studied before and during propranolol therapy in eight normal renin essential hypertensive patients; four were known ‘responders’ and four, age-matched ‘non-responders’ to previous β...
Articles
Mechanisms of Structural Vascular Changes in Genetic Hypertension: Analyses on Cultured Vascular Smooth Muscle Cells from Spontaneously Hypertensive Rats
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Journal:
Clinical Science
Clin Sci (Lond) (1981) 61 (s7): 121s–123s.
Published: 01 December 1981
..., and ornithine decarboxylase (ODC) activity of SMC were increased in SHR and SHRSP in comparison with WKY rats. 4. The application of isoprenaline but not noradrenaline to the culture media increased ODC activity acutely in SMC from WKY rats and this increase was blocked by propranolol. 5. These results indicate...
Articles
Effect of Propranolol Therapy on Aldosterone Responses to Angiotensin II and Adrenocorticotropic Hormone in Essential Hypertension
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Journal:
Clinical Science
Clin Sci (Lond) (1981) 61 (1): 107–110.
Published: 01 July 1981
...M. S. Golub; M. L. Tuck; D. B. Fittingoff 1. The plasma aldosterone responses to exogenous angiotensin II and adrenocorticotropic hormone (ACTH) were studied before and after 1 month of propranolol therapy (120–240 mg/day) in eight patients with essential hypertension. 2. Basal supine plasma renin...
Articles
The Effect of Prolonged Administration of Propranolol and Timolol on the Growth and the Heart of Growing Rabbits
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Journal:
Clinical Science
Clin Sci (Lond) (1981) 60 (1): 33–40.
Published: 01 January 1981
...K. L. Evemy; P. Cummins; W. A. Littler 1. The effect of prolonged administration of β-adrenoreceptor-blocking agents was studied in growing rabbits. Equivalent doses of propranolol and timolol were given parenterally for 8 weeks. 2. Animals given propranolol had a significantly lower heart rate...
Articles
β -Adrenoreceptor-Blocking Agents and the Blood-Brain Barrier
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Journal:
Clinical Science
Clin Sci (Lond) (1980) 59 (s6): 453s–455s.
Published: 01 December 1980
...J. M. Cruickshank; G. Neil-Dwyer; M. M. Cameron; J. McAinsh 1. Sixteen neurosurgical patients received (oral) β-adrenoreceptor-blocking agents (β-receptor blockers) for 3–22 days. 2. Lipophilic β-receptor blockers (propranolol) and metoprolol appeared in cerebrospinal fluid at concentrations...
Articles
Renal Blood Flow and Noradrenaline Secretion during Treatment with Propranolol
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Journal:
Clinical Science
Clin Sci (Lond) (1980) 59 (s6): 477s–478s.
Published: 01 December 1980
...P. W. De Leeuw; R. Punt; W. H. Birkenhager 1. Fifty-five patients with uncomplicated essential hypertension were admitted to hospital, where 25 of them were treated with propranolol (average daily dose 240 mg) and 30 were left untreated. 2. In all of them renal arteriography was carried out, after...
Articles
Renin Release during Head-up Tilt Occurs Independently of Sympathetic Nervous Activity in Tetraplegic Man
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Journal:
Clinical Science
Clin Sci (Lond) (1980) 59 (4): 251–256.
Published: 01 October 1980
... pressure, heart rate and concentrations of plasma noradrenaline, plasma adrenaline and plasma renin activity were measured during head-up tilt to 45° before and after acute β-adrenoreceptor blockade with intravenous propranolol. 2. In the normal subjects there were minimal changes in blood pressure during...
Articles
Effect of Propranolol on Heart Rate, Blood Pressure and Plasma Noradrenaline during Coitus in the Rabbit
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Journal:
Clinical Science
Clin Sci (Lond) (1980) 59 (4): 231–236.
Published: 01 October 1980
... to 165 ± 4 mmHg, and plasma concentration of noradrenaline from 2.07 ± 0.21 to 5.02 ± 0.26 nmol/l. The maximum heart rate did not occur until after the peak in blood pressure. 3. Propranolol had no effect on the power expended during coitus, but there was a dose dependent fall in the changes in heart...
Articles
Cardiogenic Hypertension: Experimental Evidence from a Comparison between Intravenous and Intracoronary Administration of Dobutamine in Conscious Dogs
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Journal:
Clinical Science
Clin Sci (Lond) (1980) 58 (4): 271–277.
Published: 01 April 1980
... dobutamine, 1.56 × 10 −8 mol min −1 kg −1 , intravenously for a 7 day period and seven conscious dogs were given dobutamine, 1.51 × 10 −8 mol min −1 kg −1 , into the left coronary artery under oral propranolol treatment for the same period while arterial pressure, cardiac output (electromagnetic flowmeter...
Articles
Comparative β -Adrenoreceptor-Blocking Effects and Pharmacokinetics of Propranolol and Pindolol in Hypertensive Africans
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Journal:
Clinical Science
Clin Sci (Lond) (1979) 57 (s5): 393s–396s.
Published: 01 December 1979
...L. A. Salako; A. O. Falase; A. Fadeke Aderounmu 1. The β-adrenoreceptor-blocking effects of pindolol were compared with those of propranolol and a placebo in a double-blind cross-over trial involving nine hypertensive African patients. 2. Heart rate, systolic blood pressure and diastolic blood...
Articles
Influence of Selective and Non-Selective β -Adrenoreceptor Blockade on the Haemodynamic Effect of Adrenaline during Combined Antihypertensive Drug Therapy
Available to PurchaseH. Houben, TH. Thien, TH. De Boo, W. Lemmens, C. L. A. Van Herwaarden, J. F. M. Fennis, A. Van 'T Laar
Journal:
Clinical Science
Clin Sci (Lond) (1979) 57 (s5): 397s–399s.
Published: 01 December 1979
...H. Houben; TH. Thien; TH. De Boo; W. Lemmens; C. L. A. Van Herwaarden; J. F. M. Fennis; A. Van 'T Laar 1. Haemodynamic effects of adrenaline were studied in 27 hypertensive patients, successively during treatment with propranolol and metoprolol. In 12 patients β-adrenoreceptor blockade was combined...
Articles
Observations on Some Properties of a Long-Acting Preparation of Propranolol
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Journal:
Clinical Science
Clin Sci (Lond) (1979) 57 (s5): 409s–411s.
Published: 01 December 1979
...R. G. Shanks; J. D. Neill; W. J. Leahey; M. P. S. Varma 1. The effects of 160 mg of propranolol and 160 mg of a long-acting (LA) formulation of propranolol were studied in healthy subjects. 2. Both drugs reduced an exercise tachycardia but the peak was less and the 24 h effect greater after long...
Articles
Objective Measurement of Performance during Acute Stress in Patients with Essential Hypertension: Assessment of the Effects of Propranolol and Metoprolol
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Journal:
Clinical Science
Clin Sci (Lond) (1979) 57 (s5): 413s–415s.
Published: 01 December 1979
...F. G. Dunn; A. R. Lorimer; T. D. V. Lawrie 1. A standardized method of objectively measuring performance during simulated car driving is described. 2. The effect of a single dose of propranolol and metoprolol were compared with placebo in two groups of patients with untreated essential hypertension...
Articles
The Pathogenesis of Propranolol-Withdrawal Syndrome in Essential Hypertension
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Journal:
Clinical Science
Clin Sci (Lond) (1979) 57 (s5): 417s–420s.
Published: 01 December 1979
...B. Ø. Kristensen; EVA Steiness; J. Weeke 1. In hypertension, the β-adrenoreceptor-blocker-withdrawal syndrome comprises tachycardia, sweating, tremor and general malaise, symptoms resembling thyrotoxicosis. 2. The effect of abrupt cessation of propranolol on serum concentrations of thyroxine (T 4...
Articles
Does the Renin—Angiotensin System Maintain Blood Pressure in Both Hypertensive and Normotensive Subjects? a Comparison of Propranolol, Saralasin and Captopril
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Journal:
Clinical Science
Clin Sci (Lond) (1979) 57 (s5): 145s–148s.
Published: 01 December 1979
...G. A. MacGregor; N. D. Markandu; J. E. Roulston 1. Propranolol, saralasin and captopril changed blood pressure in normotensive as well as hypertensive subjects. 2. The percentage change in blood pressure with these three drugs for a given plasma renin activity was similar in normotensive...
Articles
Protein Synthesis and Composition of Cardiac and Vascular Tissue in Spontaneously Hypertensive Rats and the Effects of β-Adrenergic Antagonist Treatment
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Journal:
Clinical Science
Clin Sci (Lond) (1979) 57 (s5): 39s–41s.
Published: 01 December 1979
...S.-L. Boström; J. Fryklund 1. Propranolol and metoprolol were given in the diet of spontaneously hypertensive (SH) rats during the development of hypertension. 2. At the early established phase of hypertension, protein synthesis and protein composition of the left ventricle, aorta, mesenteric...
Articles
Effect of Propranolol on the Ventilatory Response to Hypercapnia in Man
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Journal:
Clinical Science
Clin Sci (Lond) (1979) 57 (5): 465–468.
Published: 01 November 1979
...P. W. Trembath; Elizabeth A. Taylor; J. Varley; P. Turner 1. The effect of a single oral dose of propranolol on the ventilatory response to hypercapnia has been studied in five healthy subjects. 2. Propranolol produced a small but significant reduction in the slope of the ventilation/end-tidal P co...
Articles
The Role of the Baroreceptor Reflex in the Cardiovascular Effects of Propranolol in the Conscious Spontaneously Hypertensive Rat
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Journal:
Clinical Science
Clin Sci (Lond) (1979) 56 (2): 163–167.
Published: 01 February 1979
...H. A. J. Struyker-Boudier; J. F. Smits; H. Van Essen 1. The role of baroreceptors in the cardiovascular mechanism of action of dl-propranolol has been studied by comparing the acute effects of subcutaneous injection of 1 and 5 mg/kg (3·3 × 10 −6 and 16·5 × 10 −6 mol/kg) of this drug in conscious...
Articles
Evidence for Activation of Circulating Inactive Renin by the Human Kidney
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Journal:
Clinical Science
Clin Sci (Lond) (1979) 56 (2): 115–120.
Published: 01 February 1979
... not different from arterial values both before and after diazoxide. 2. Sixteen patients with EHT received propranolol, 80 mg, four times a day. Six of them had a first injection of diazoxide the day before propranolol was started and a second one after 10–14 days of propranolol treatment. Peripheral vein active...
Articles
Acid-Activated Renin Responses to Hydrochlorothiazide, Propranolol and Indomethacin
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Journal:
Clinical Science
Clin Sci Mol Med (1978) 55 (s4): 151s–153s.
Published: 01 December 1978
...J. K. McKenzie; E. Reisin 1. Six essential hypertensive patients (five with low renin) were treated in successive weeks with placebo; hydrochlorothiazide 100 mg (382 μmol)/day; hydrochlorothiazide and 50 mmol of sodium/day diet; hydrochlorothiazide, 50 mmol of sodium diet and propranolol 160 mg...
Articles
Effect of Selective and Non-Selective β-Adrenoreceptor Blockade on Calf Blood Flow in Hypertensive Patients
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Journal:
Clinical Science
Clin Sci Mol Med (1978) 55 (s4): 287s–290s.
Published: 01 December 1978
...D. L. Clement 1. Dose—response curves of isoprenaline were constructed in nine hypertensive patients before and after either propranolol or metoprolol. 2. The decrease of diastolic blood pressure and increase of heart rate with isoprenaline were significantly more inhibited by propranolol than...
Articles
Effects of Enkephalins on Arterial Blood Pressure are Reduced by Propranolol
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Journal:
Clinical Science
Clin Sci Mol Med (1978) 55 (s4): 237s–241s.
Published: 01 December 1978
... intravenous injection, blood pressure was increased by methionine—enkephalin and leucine—enkephalin, but heart rate was increased by methionine—enkephalin only. 3. Propranolol treatment reduced the increases in blood pressure following intraventricular methionine—enkephalin and leucine—enkephalin, while only...
Articles
β-Adrenoreceptor-Blocking Agents and Lipid Metabolism
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Journal:
Clinical Science
Clin Sci Mol Med (1978) 55 (s4): 323s–324s.
Published: 01 December 1978
...J. D. F. England; A. S. P. Hua; J. Shaw 1. Chlorothiazide twice a day plus atenolol, metoprolol, pindolol and propranolol in single daily doses administered to patients with essential hypertension achieved effective control of blood pressure. 2. Each β-adrenoreceptor-blocking drug was associated...
Articles
Plasma Adrenaline and Noradrenaline in Essential Hypertension and after Long-Term Treatment with β-Adrenoreceptor-Blocking Agents
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Journal:
Clinical Science
Clin Sci Mol Med (1978) 55 (s4): 97s–100s.
Published: 01 December 1978
... with control subjects, either in supine or in upright positions, whereas no significant differences were found in plasma noradrenaline. 3. Six hypertensive patients were chronically treated with β-adrenoreceptor-blocking agents (five with propranolol and one with pindolol). Plasma noradrenaline...
Articles
Propranolol and the Ventilatory Response to Hypoxia and Hypercapnia in Normal Man
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Journal:
Clinical Science
Clin Sci Mol Med (1978) 55 (5): 491–497.
Published: 01 November 1978
...J. M. Patrick; Janice Tutty; S. B. Pearson 1. The effect on respiration of a single dose of propranolol has been studied in normal subjects. 2. The degree of β-adrenoreceptor blockade was assessed in terms of the impaired heart-rate response to progressive exercise and the plasma propranolol...
Articles
Natriuretic Effect of Propranolol on Dogs with Chronic Bile-Duct Ligation
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Journal:
Clinical Science
Clin Sci Mol Med (1978) 54 (6): 603–607.
Published: 01 June 1978
...-adrenergic blockade on sodium excretion in dogs with bile-duct ligation during extracellular hypotonic volume expansion. 3. Urinary excretion of sodium and fractional excretion of sodium rose significantly after 5 days of oral dl-propranolol administration to dogs with bile-duct ligation. 4...
Articles
The Effect of α -Adrenoreceptor Stimulation on the Airways of Normal and Asthmatic Man
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Journal:
Clinical Science
Clin Sci Mol Med (1978) 54 (3): 283–289.
Published: 01 March 1978
... 1978 α-adrenoreceptor agonists β-adrenoreceptor blockade asthma atropine bronchi isoprenaline methoxamine propranolol Clinical Science and Molecular Medicine, (1978), 54, 283-289 The effect of -adrenoreceptor stimulation on the airways of normal and asthmatic man P. D. SNASHALL, FRANCES...
Articles
Comparison of the Effect of Two Groups of Diuretics on Renin Secretion in the Anaesthetized Dog
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Journal:
Clinical Science
Clin Sci Mol Med (1977) 52 (2): 171–182.
Published: 01 February 1977
...-propranolol or by a bilateral ureterovenous anastomosis which prevents salt and water loss. 3. Clopamide, metolazone and indapamide do not cause an immediate rise in renin secretion. Renin hypersecretion is induced only 1 h after intravenous injection of these diuretics. 4. Renin secretion was studied for 6 h...
Articles
Effect of Propranolol on Blood Pressure and Renin in Renal Hypertension in the Rat
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Journal:
Clinical Science
Clin Sci Mol Med (1977) 52 (1): 107–109.
Published: 01 January 1977
...M. Fernandes; G. Onesti; R. Fiorentini; A. B. Gould; K. E. Kim; C. Swartz 1. Propranolol was administered to groups of mature rats before and during the development of renal hypertension induced by ligation of the aorta between the renal arteries. 2. At a dose 10 μmol (3 mg) of propranolol/kg...
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