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Keywords: prostanoid
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Clin Sci (Lond) (2014) 126 (2): 111–121.
Published: 13 September 2013
...Raquel Hernanz; Ana M. Briones; Mercedes Salaices; María J. Alonso Elevated production of prostanoids from the constitutive (COX-1) or inducible (COX-2) cyclo-oxygenases has been involved in the alterations in vascular function, structure and mechanical properties observed in cardiovascular...
Clin Sci (Lond) (2010) 118 (11): 657–668.
Published: 09 March 2010
... prostanoid reactive oxygen species superoxide anion Several studies in animals and humans have demonstrated that ethanol consumption is associated with cardiovascular pathologies such as hypertension [ 1 – 3 ]. In fact, ethanol can evoke direct contractile responses in different blood vessels [ 4...
Clin Sci (Lond) (2007) 113 (7): 297–311.
Published: 03 September 2007
...Rania Nasrallah; Jordan Clark; Richard L. Hébert There are five major PGs (prostaglandins/prostanoids) produced from arachidonic acid via the COX (cyclo-oxygenase) pathway: PGE 2 , PGI 2 (prostacyclin), PGD 2 , PGF 2α and TXA 2 (thromboxane A 2 ). They exert many biological effects through specific...
Clin Sci (Lond) (2005) 109 (1): 45–54.
Published: 23 June 2005
... Figure 3 ). In previous studies performed predominantly on forearm cutaneous circulation of male subjects who were less than 50 years old, aspirin either had no effect [ 14 , 32 ] or reduced dilator responses evoked by iontophoresis of ACh, implicating vasodilator prostanoids in the response [ 15...
Clin Sci (Lond) (2002) 103 (s2002): 13S–15S.
Published: 01 September 2002
... Foundation, Rochester, MN 55905, U.S.A. © 2002 The Biochemical Society and the Medical Research Society 2002 aorta carotid artery endothelium high-fat diet prostanoid risk factors thromboxane vascular vasoconstriction 13SClinical Science (2002) 103 (Suppl. 48), 13S 15S (Printed in Great...
Clin Sci (Lond) (2002) 103 (s2002): 298S–301S.
Published: 01 September 2002
... substances such as endothelin A receptor (ET A ) antagonists and prostanoids have been used to improve haemodynamics and clinical outcome. We compared the hemodynamic response to BQ-123 (an ET A receptor antagonist) and prostacyclin or its analogue iloprost in ten patients (four men) with a mean age of 35.9...