...Raquel Hernanz; Ana M. Briones; Mercedes Salaices; María J. Alonso Elevated production of prostanoids from the constitutive (COX-1) or inducible (COX-2) cyclo-oxygenases has been involved in the alterations in vascular function, structure and mechanical properties observed in cardiovascular...

... on the basis the H 2 O 2 standard curve. aorta calcium hydrogen peroxide prostanoid reactive oxygen species superoxide anion Several studies in animals and humans have demonstrated that ethanol consumption is associated with cardiovascular pathologies such as hypertension [ 1 – 3...

...Rania Nasrallah; Jordan Clark; Richard L. Hébert There are five major PGs (prostaglandins/prostanoids) produced from arachidonic acid via the COX (cyclo-oxygenase) pathway: PGE 2 , PGI 2 (prostacyclin), PGD 2 , PGF 2α and TXA 2 (thromboxane A 2 ). They exert many biological effects through specific...

... acetylcholine endothelium cyclo-oxygenase prostanoid Raynaud's disease vasodilatation Iontophoresis of ACh and its vehicle before and after aspirin treatment was performed on 15 women with PR (pre-menopausal, 34.4±10 years; post-menopausal, 62.2±7.9 years) and on 15 control women (pre-menopausal, 34.3...

..., MN 55905, U.S.A. © 2002 The Biochemical Society and the Medical Research Society 2002 aorta carotid artery endothelium high-fat diet prostanoid risk factors thromboxane vascular vasoconstriction 13SClinical Science (2002) 103 (Suppl. 48), 13S 15S (Printed in Great Britain...

... substances such as endothelin A receptor (ET A ) antagonists and prostanoids have been used to improve haemodynamics and clinical outcome. We compared the hemodynamic response to BQ-123 (an ET A receptor antagonist) and prostacyclin or its analogue iloprost in ten patients (four men) with a mean age of 35.9...