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Keywords: protein degradation
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Clin Sci (Lond) (2012) 122 (3): 133–142.
Published: 11 October 2011
..., we investigated whether muscle protein degradation is increased in critically ill patients with sepsis and which proteolytic enzyme systems are involved in this degradation. Eight patients and seven healthy volunteers were studied. In vivo muscle protein kinetics was measured using arteriovenous...
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Clin Sci (Lond) (2007) 112 (9): 499–506.
Published: 02 April 2007
... dysfunction proteasome protein degradation sepsis skeletal muscle Patients with septic shock in the ICU (intensive care unit) are prone to develop muscle wasting, a condition that is mainly manifested in skeletal muscle. The net loss of muscle proteins could depend on decreased protein synthesis...
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Clin Sci (Lond) (1996) 90 (6): 457–466.
Published: 01 June 1996
... The Biochemical Society and the Medical Research Society 1996 amino acid membrane transport phenylalanine protein degradation tracer Clinical Science (1996) W, 457466 (Printed in Great Britain) Muscle protein and amino acid turnover in rats in v iva effects of short-term and prolonged starvation 1...
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Clin Sci (Lond) (1991) 81 (5): 611–619.
Published: 01 November 1991
... rates ( k s ), the whole-body fractional protein degradation rate ( k d ), the capacity for protein synthesis ( C s ) and the efficiency of protein synthesis ( k RNA ) in vivo in fed and fasted (1, 5 and about 9 days) 400 g rats. 2. One day of starvation resulted in a reduced k s and an increased k d...
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Clin Sci (Lond) (1990) 79 (5): 537–542.
Published: 01 November 1990
...S. B. Ireland; P. M. Stewart 1. The effect of uraemia on the rates of protein synthesis and protein degradation in liver, heart and vastus lateralis muscle were examined in the rat. Uraemia was induced by a five-sixths nephrectomy and the rates of protein turnover were compared with pair-fed sham...
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Clin Sci (Lond) (1981) 60 (3): 319–326.
Published: 01 March 1981
...K. Lundholm; S. Edström; L. Ekman; I. Karlberg; P. Walker; T. Scherstén 1. The protein degradation rate of human skeletal muscle was evaluated in vitro in isolated fibre bundles from the rectus abdominus muscle by measuring the tyrosine released from muscle tissue proteins. Protein metabolism...
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Clin Sci (Lond) (1979) 57 (6): 535–544.
Published: 01 December 1979
...F. J. Ballard; F. M. Tomas; L. M. Pope; P. G. Hendry; B. E. James; R. A. MacMahon 1. Myofibrillar protein degradation has been measured by the rate of 3-methylhistidine excretion in premature infants weighing between 635 g and 1295 g. Analyses were made in conjunction with 1–3 day nitrogen balance...
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Clin Sci (Lond) (1979) 56 (4): 347–352.
Published: 01 April 1979
...F. J. Ballard; F. M. Tomas; L. M. Stern 1. Myofibrillar protein degradation has been measured in patients with Duchenne muscular dystrophy, normal boys, adult males and Duchenne carriers by the rate of 3-methylhistidine excretion after transfer of subjects to a meat-free diet. 2. Although absolute...
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