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Keywords: proteolysis
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Articles
Clin Sci (Lond) (2010) 119 (11): 465–466.
Published: 17 August 2010
... 7 2010 15 7 2010 15 7 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 amino acid cachexia heart failure inflammation insulin proteolysis sarcopenia The syndrome of CHF [chronic HF (heart failure)] is a complex multi-organ response mechanism to...
Articles
Clin Sci (Lond) (2010) 119 (11): 467–476.
Published: 17 August 2010
... of nutritional deprivation, HF patients demonstrate an impaired muscle protein anabolic response to meal-related stimuli, due to an inability to suppress muscle proteolysis, and that this diminished protein anabolic response correlates with markers of immune activation. The inability to stimulate...
Articles
Clin Sci (Lond) (2001) 100 (4): 411–417.
Published: 05 March 2001
... 12 2000 The Biochemical Society and the Medical Research Society © 2001 2001 gastric juice mucolysis proteolysis 411Clinical Science (2001) 100, 411 417 (Printed in Great Britain) Mucosal protective effects of ecabet sodium: pepsin inhibition and interaction with mucus J. P. PEARSON...
Articles
Clin Sci (Lond) (2000) 99 (3): 181–187.
Published: 01 August 2000
... cachexia is at least, in part, regulated by the ubiquitin–proteasome proteolytic pathway. burn injury cachexia muscle proteasome proteolysis ubiquitin Correspondence : Professor Per-Olof Hasselgren (e-mail hasselp@uc.edu ). 1 2 2000 20 3 2000 18 4 2000 The...
Articles
Clin Sci (Lond) (1998) 95 (2): 225–233.
Published: 01 August 1998
..., lactacystin and β-lactone supports the concept that the ubiquitin–proteasome pathway plays a central role in burn-induced muscle proteolysis. Because the proteasome has multiple important functions in the cell, in addition to regulating general protein breakdown, further studies are needed to test the role of...
Articles
Clin Sci (Lond) (1994) 87 (5): 607–618.
Published: 01 November 1994
... synthesis by protein deficiency, mediated by reductions in both ribosomal capacity and activity in the 0.5% protein group, which preceded growth inhibition in the 7% and 3.5% groups, and which was progressive with time. Transient increases in proteolysis contributed to the growth inhibition is some groups...
Articles
Clin Sci (Lond) (1990) 79 (5): 457–466.
Published: 01 November 1990
... most other amino acids, including phenylalanine, which fell by 34%. Plasma insulin levels were unchanged from basal levels (8 ± 1 μ-units/ml). 3. Whole-body phenylalanine flux, an index of proteolysis, was significantly suppressed by branched-chain amino acid infusion ( P < 0.002), and forearm...
Articles
Clin Sci (Lond) (1990) 78 (3): 265–271.
Published: 01 March 1990
...D. A. Hutton; J. P. Pearson; A. Allen; S. N. E. Foster 1. Mucolytic (mucus solubilizing) activity in human faeces has been characterized with both purified human and pig colonic mucin and shown to be mediated by proteolysis. 2. Mucolytic activity was demonstrated by: (i) a drop in mucin viscosity...
Articles
Clin Sci (Lond) (1989) 77 (1): 35–41.
Published: 01 July 1989
...-dependent manner, from 11% at 10 −10 mol/l to 68% at 10 −3 mol/l. elastase emphysema endotoxin neutrophil proteolysis tumour necrosis factor © 1989 The Biochemical Society and the Medical Research Society 1989 27 7 1988 18 11 1988 Clinical Science ( 1989) 77,3541 35 Effects of...
Articles
Clin Sci (Lond) (1983) 65 (4): 373–381.
Published: 01 October 1983
... α 1 -antitrypsin leucocyte elastase lung secretions proteolysis Clinical Science (1983) 65, 373-381 373 The immunological assessment of q-antitrypsin with reference to its function in bronchial secretions R. A. STOCKLEY AND S . C. AFFORD The General Hospital, Birmingham, U.K. (Received 25...
Articles
Clin Sci (Lond) (1983) 64 (2): 119–126.
Published: 01 February 1983
... 1983 endopeptidases proteinase inhibitors proteolysis pulmonary emphysema Clinical Science (1983) 64,119-126 119 I EDITORIAL REVIEW I Proteolytic enzymes, their inhibitors and lung diseases R. A. S T O C K L E Y The General Hospital, Birmingham, U.K. The pathogenesis of many acute and...