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Keywords: proteomics
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Clin Sci (Lond) (2024) 138 (18): 1173–1177.
Published: 18 September 2024
... that physiological atrial enlargement resulted from increased atrial myocyte size and was associated with preserved atrial function, as determined by maintained LA ejection fraction (EF). The proteomic profile of IGF1R transgenic (Tg) mice was enriched for metabolic remodeling and showed a protein expression pattern...
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Clin Sci (Lond) (2018) 132 (19): 2117–2120.
Published: 05 October 2018
... localise predominantly to the endosomal-recycling compartment . Biochem. Biophys. Res. Commun. 359 , 277 – 284 10.1016/j.bbrc.2007.05.100 17543888 17 Harshman S.W. , Canella A. , Ciarlariello P.D. , Agarwal K. , Branson O.E. , Rocci A. ( 2016 ) Proteomic...
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Clin Sci (Lond) (2016) 130 (12): 1027–1038.
Published: 06 May 2016
... from four AAA patients and four controls were analysed by a label-free proteomic approach. Among identified proteins, paraoxonase-1 (PON1) was decreased in plasma of AAA patients compared with controls, which was further validated in a bigger cohort of samples by ELISA. The phenylesterase enzymatic...
Includes: Supplementary data
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Clin Sci (Lond) (2015) 129 (1): 27–38.
Published: 01 April 2015
... mechanism and causal risk factors for plaque rupture remain unclear. To identify a potential molecule that can influence atherosclerotic plaque rupture, we investigated protein expression in serum from patients with acute myocardial infarction (AMI) and stable angina (SA), using proteomic analysis...
Includes: Supplementary data
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Clin Sci (Lond) (2009) 116 (9): 721–730.
Published: 02 April 2009
... and high mortality rate. Its pathophysiology and molecular mechanisms are complicated and remain poorly understood. In the present study, we performed a proteomics investigation to characterize early host responses to sepsis as determined by an altered plasma proteome in a porcine model of peritonitis...
Includes: Supplementary data
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Clin Sci (Lond) (2008) 114 (7): 499–507.
Published: 29 February 2008
... The Authors Journal compilation © 2008 Biochemical Society 2008 early insulin response plasma protein proteomics surface-enhanced laser-desorption ionization–time-of-flight MS (SELDI-TOF MS) Type 2 diabetes mellitus ULSAM (Uppsala Longitudinal Study of Adult Men) The pathophysiology of T2DM...
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Clin Sci (Lond) (2005) 109 (5): 421–430.
Published: 24 October 2005
...Bernardo C. Vidal, Jr; Joseph V. Bonventre; Stephen I-Hong Hsu Proteomics is widely envisioned as playing a significant role in the translation of genomics to clinically useful applications, especially in the areas of diagnostics and prognostics. In the diagnosis and treatment of kidney disease...
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Clin Sci (Lond) (2005) 108 (5): 369–383.
Published: 22 April 2005
...Walter KOLCH; Harald MISCHAK; Andrew R. PITT The enormous progress in proteomics, enabled by recent advances in MS (mass spectrometry), has brought protein analysis back into the limelight of cancer research, reviving old areas as well as opening new fields of study. In this review, we discuss...
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Clin Sci (Lond) (2004) 107 (5): 485–495.
Published: 26 October 2004
... indicative of ‘diabetic renal damage’. We also found this pattern in 35% of those patients who had low-grade albuminuria and in 4% of patients with normal albumin excretion. Moreover, we could identify several of the indicative polypeptides using MS/MS sequencing. We conclude that proteomic analysis with CE...
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