... in both hepatectomized and normal rats and there was no difference in the proportion of pteroylpentaglutamate to other forms of folate in the regenerating or resting liver. 3. Folate concentrations were also measured in leucocytes from normal and leukaemic patients. 4. Pteroylpolyglutamates constituted...

... cells but had no consistent effect in normal cells. 4. Normal and vitamin B 12 -deficient PHA-stimulated lymphocytes took up [ 3 H]folic acid and after 72 h incubation converted this largely into pteroylpolyglutamate forms. 5. The proportion of labelled lymphocyte folate as pteroylpolyglutamate after...

... with Lactobacillus casei and Streptococcus faecalis , with and without deconjugation of whole liver pteroylpolyglutamates (conjugated folates). Individual folate compounds were identified by microbiological assay after fractionation of liver folates by DEAE cellulose ion-exchange column chromatography. 3. Liver...

... pteroylpolyglutamate hydrolase in vitro. 5. Tests of absorption of pteroylglutamic acid (folic acid) and pteroylpolyglutamates in controls and women taking oral contraceptives showed no difference between the two groups, provided the subjects were presaturated with pteroylglutamic acid. Without presaturation, the rise...