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Keywords: pulmonary emphysema
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Clin Sci (Lond) (1983) 64 (2): 119–126.
Published: 01 February 1983
.... Much of this interest owes its existence to two observations in the early 1960s: firstly, the recognition that subjects with an inherited deficiency of α 1 -antitrypsin (α 1 -AT; the main serum inhibitor of proteolytic enzymes) had a high incidence of pulmonary emphysema [1], and secondly...