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Keywords: pulmonary fibrosis
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Clin Sci (Lond) (2023) 137 (11): 895–912.
Published: 14 June 2023
... findings from these two approaches in the context of four common respiratory diseases (asthma, chronic obstructive pulmonary disease, pulmonary fibrosis, and respiratory infection). Potential methods used to identify and measure human circadian oscillations are also discussed as these will be useful...
Clin Sci (Lond) (2022) 136 (16): 1229–1240.
Published: 31 August 2022
... therapy. The most common form is referred to as ‘idiopathic’ since a causal agent or specific association has not been determined; the strongest risk factor for idiopathic pulmonary fibrosis is aging. Emerging studies indicate that targeting certain components of aging biology may be effective...
Clin Sci (Lond) (2020) 134 (7): 889–905.
Published: 17 April 2020
... that contribute to idiopathic pulmonary fibrosis (IPF); a lethal disease that manifests primarily in the elderly. Whilst evidence is accumulating that GMP-AMP synthase (cGAS) is crucial in perpetuating senescence by binding damaged DNA released into the cytosol, its role in IPF is not known. The present study...
Includes: Supplementary data
Clin Sci (Lond) (2015) 128 (4): 235–256.
Published: 17 October 2014
... of the models currently used in the settings of asthma, idiopathic pulmonary fibrosis and COPD. The ultimate hope is that this will contribute to a more rational, efficient and sustainable development of a range of new treatments for respiratory diseases that continue to cause substantial morbidity...
Clin Sci (Lond) (2005) 108 (6): 479–491.
Published: 24 May 2005
..., as well as structural, cells pertinent to fibrogenesis. In general, leukotrienes promote, whereas prostaglandin E 2 opposes, fibrogenic responses. An imbalance of eicosanoids also exists in pulmonary fibrosis, which favours the production of leukotrienes over prostaglandin E 2 . This review highlights...
Clin Sci (Lond) (1981) 61 (6): 781–784.
Published: 01 December 1981
...J. Savoy; S. Dhingra; N. R. Anthonisen 1. in 10 patients with pulmonary fibrosis and in seven control subjects, we measured the pressure at the mouth 0.1 s after onset of an inspiration against occluded airway ( P 0.1 ), minute ventilation ( V I ), breathing frequency ( f r ), tidal volume ( V T...