... 12 2 2016 Correspondence: Cathal McCarthy (email cmccarthy@ucc.ie ). antioxidants mitochondria pre-eclampsia reactive oxygen species (ROS) Pre-eclampsia is a multisystemic disorder of pregnancy, which affects more than eight million pregnancies worldwide annually...

...-regulated kinase (ERK) leptin reactive oxygen species (ROS) transcriptional activity • Mechanical cyclic stretch of cardiomyocytes causes cardiac hypertrophy through cardiac-restricted gene expression of proteins, including leptin; however, the mechanisms and regulatory pathways underlying...

... inhibition reactive oxygen species (ROS) small artery vascular remodelling • Aliskiren represents an antihypertensive agent with a new mechanism based on the inhibition of a catalytic activity of the renin enzyme, which prevents the activation of the RAS cascade. • In the present study, we...

... wall, and chronic systemic and arterial wall inflammation. 25 10 2010 25 1 2011 10 2 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 atherosclerosis exercise inflammation myokine obesity reactive oxygen species (ROS) sedentary lifestyle...

... 2010 © The Authors Journal compilation © 2011 Biochemical Society 2011 immune system melanocyte reactive oxygen species (ROS) skin T-cell vitiligo BH 4 cofactor is essential for various enzyme activities and is present in probably all cells. Six and seven isoforms of BH 4...

... (NO • ) oxidative stress reactive oxygen species (ROS) The brain has minimal storage of energy sources, making it exceptionally sensitive to interruptions in its blood supply. It is not therefore surprising that the cerebral circulation is a highly specialized vascular bed with a number of unique...

...) according to the manufacturer's recommendations. atherosclerosis mitogen-activated protein kinase (MAPK) reactive oxygen species (ROS) resistin smooth muscle cell signal transducer and activator of transcription (STAT) stretch Resistin is an adipocytokine and has been shown to have...

...). Correspondence: Professor Philip Newsholme (email philip.newsholme@ucd.ie ). 17 8 2009 6 10 2009 8 10 2009 © The Authors Journal compilation © 2010 Biochemical Society 2010 diabetes endothelial vascular cell exercise nitric oxide pancreatic β-cell reactive oxygen species (ROS...

... circulation microvascular circulation nitric oxide reactive oxygen species (ROS) tumour necrosis factor-α (TNF-α) Stem and progenitor cells possess the ability to self-regenerate and differentiate into many cell types, including cardiovascular-specific forms. The role of stem cells and progenitor...

... 2007 © The Authors Journal compilation © 2008 Biochemical Society 2008 antioxidant ischaemia/reperfusion liver oxidative stress Pringle manoeuvre reactive oxygen species (ROS) Ten patients (six male and four female) undergoing partial hepatectomy for secondary liver...

... 9 2007 11 10 2007 11 10 2007 © The Authors Journal compilation © 2008 Biochemical Society 2008 bioactive phenolic endothelium-dependent relaxation endothelial nitric oxide synthase (eNOS) grape seed extract phosphoinositide 3-kinase (PI3K) reactive oxygen species (ROS...

... the C242T functionality in lymphocytes and monocytes [ 88 ]. cardiovascular disease NADPH oxidase oxidative stress p22 phox subunit reactive oxygen species (ROS) superoxide anion Oxidative stress is defined as an imbalanced redox state where pro-oxidants overwhelm antioxidant...

... 2006 cellular homoeostasis host defence NADPH oxidase pathogenesis phagocyte reactive oxygen species (ROS) superoxide anion ROS (reactive oxygen species) represent a diverse family of molecules that play roles in a myriad of physiological and pathophysiological events. ROS...

... mitochondria NADPH oxidase reactive oxygen species (ROS) A major focus within the basic science community studying hypertension is related to the role of ROS (reactive oxygen species). The broad definition of ROS includes oxygen-containing species that are all capable of reacting with proteins...

..., 813 71 Bratislava, Slovak Republic (email olga.pechanova@savba.sk ). 21 7 2005 7 9 2005 20 10 2005 20 10 2005 The Biochemical Society 2006 N -acetylcysteine genetic hypertension nuclear factor κB (NF-κB) nitric oxide synthase reactive oxygen species (ROS...

...) was found to be the major mechanism of ROS production induced by OA and LA in Jurkat and Raji cells. 23 9 2004 24 11 2004 24 11 2004 The Biochemical Society 2005 linoleic acid oleic acid lymphocyte protein kinase C (PKC) reactive oxygen species (ROS) Results...