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Keywords: reactive oxygen species (ROS)
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Articles
Clin Sci (Lond) (2016) 130 (14): 1179–1184.
Published: 01 June 2016
... and, operating with reduced glutathione as a cofactor, are proposed to scavenge ROS at higher intracellular concentrations. Catalase has an inferior affinity for H 2 O 2 and is limited to peroxisomes [ 16 ]. antioxidants mitochondria pre-eclampsia reactive oxygen species (ROS) Pre-eclampsia...
Articles
Clin Sci (Lond) (2014) 126 (7): 483–495.
Published: 11 December 2013
... be prevented by ARBs, which repress the effect of AngII and leptin. angiotensin II cardiomyocyte hypertrophy extracellular signal-regulated kinase (ERK) leptin reactive oxygen species (ROS) transcriptional activity AngII (10 nM exogenously added) was measured in cell lysates...
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Clin Sci (Lond) (2011) 121 (3): 91–106.
Published: 15 April 2011
..., an increase in oxidant stress, an accumulation of lipids in the arterial wall, and chronic systemic and arterial wall inflammation. atherosclerosis exercise inflammation myokine obesity reactive oxygen species (ROS) sedentary lifestyle Cardiovascular diseases remain the leading cause...
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Clin Sci (Lond) (2011) 120 (3): 99–120.
Published: 20 October 2010
... [email protected] ). 23 11 2009 26 8 2010 26 8 2010 © The Authors Journal compilation © 2011 Biochemical Society 2011 immune system melanocyte reactive oxygen species (ROS) skin T-cell vitiligo Vitiligo is a common skin disorder characterized by the acquired loss...
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Clin Sci (Lond) (2010) 119 (1): 1–17.
Published: 07 April 2010
... reactive oxygen species (ROS) The brain has minimal storage of energy sources, making it exceptionally sensitive to interruptions in its blood supply. It is not therefore surprising that the cerebral circulation is a highly specialized vascular bed with a number of unique physiological mechanisms...
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Clin Sci (Lond) (2010) 118 (3): 221–230.
Published: 01 February 2010
... Biochemical Society 2010 atherosclerosis mitogen-activated protein kinase (MAPK) reactive oxygen species (ROS) resistin smooth muscle cell signal transducer and activator of transcription (STAT) stretch Resistin is an adipocytokine and has been shown to have potent pro-inflammatory...
Includes: Supplementary data
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Clin Sci (Lond) (2009) 116 (3): 219–230.
Published: 08 January 2009
.... Correspondence: Professor Cuihua Zhang (email [email protected] ). 3 6 2008 22 7 2008 12 8 2008 inflammation macrovascular circulation microvascular circulation nitric oxide reactive oxygen species (ROS) tumour necrosis factor-α (TNF-α) IHD (ischaemic heart disease...
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Clin Sci (Lond) (2008) 114 (4): 331–337.
Published: 15 January 2008
... phosphoinositide 3-kinase (PI3K) reactive oxygen species (ROS) There is evidence that a diet rich in vegetables and fruit has a beneficial effect on blood pressure. This effect has been attributed to phenolic compounds present in the plants. These compounds have also been shown to influence endothelial...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2008) 114 (3): 173–182.
Published: 08 January 2008
... p22 phox subunit reactive oxygen species (ROS) superoxide anion NADPH oxidase is sensitively regulated by a wide range of (patho)physiologically relevant factors, which include (i) humoral factors, (ii) mechanical factors, and (iii) genetic variants [ 9 , 42 ]. Humoral factors...
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Clin Sci (Lond) (2006) 111 (1): 1–20.
Published: 14 June 2006
... cellular homoeostasis host defence NADPH oxidase pathogenesis phagocyte reactive oxygen species (ROS) superoxide anion ROS (reactive oxygen species) represent a diverse family of molecules that play roles in a myriad of physiological and pathophysiological events. ROS are comprised of highly...
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Clin Sci (Lond) (2006) 110 (2): 205–206.
Published: 17 January 2006
... deoxycorticosterone acetate (DOCA) endothelin hypertension mitochondria NADPH oxidase reactive oxygen species (ROS) A major focus within the basic science community studying hypertension is related to the role of ROS (reactive oxygen species). The broad definition of ROS includes oxygen-containing species...
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Clin Sci (Lond) (2006) 110 (2): 235–242.
Published: 17 January 2006
... parameters. N -acetylcysteine genetic hypertension nuclear factor κB (NF-κB) nitric oxide synthase reactive oxygen species (ROS) NO (nitric oxide) plays an important role in the maintenance of vascular tone, which affects the level of BP (blood pressure) [ 1 – 3 ]. In various models...
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Clin Sci (Lond) (2005) 108 (3): 245–253.
Published: 18 February 2005
..., MO, U.S.A.). Sodium bicarbonate was purchased from Labsynth products (Diadema, SP, Brazil). Dihydroethidium was obtained from Molecular Probes (Eugene, OR, U.S.A.). linoleic acid oleic acid lymphocyte protein kinase C (PKC) reactive oxygen species (ROS) Generation of moderate...