... and, operating with reduced glutathione as a cofactor, are proposed to scavenge ROS at higher intracellular concentrations. Catalase has an inferior affinity for H 2 O 2 and is limited to peroxisomes [ 16 ]. antioxidants mitochondria pre-eclampsia reactive oxygen species (ROS) Pre-eclampsia...

... be prevented by ARBs, which repress the effect of AngII and leptin. angiotensin II cardiomyocyte hypertrophy extracellular signal-regulated kinase (ERK) leptin reactive oxygen species (ROS) transcriptional activity AngII (10 nM exogenously added) was measured in cell lysates...

... The Authors Journal compilation © 2013 Biochemical Society 2013 nitric oxide renin inhibition reactive oxygen species (ROS) small artery vascular remodelling • Aliskiren represents an antihypertensive agent with a new mechanism based on the inhibition of a catalytic activity...

..., an increase in oxidant stress, an accumulation of lipids in the arterial wall, and chronic systemic and arterial wall inflammation. atherosclerosis exercise inflammation myokine obesity reactive oxygen species (ROS) sedentary lifestyle Cardiovascular diseases remain the leading cause...

... [email protected] ). 23 11 2009 26 8 2010 26 8 2010 © The Authors Journal compilation © 2011 Biochemical Society 2011 immune system melanocyte reactive oxygen species (ROS) skin T-cell vitiligo Vitiligo is a common skin disorder characterized by the acquired loss...

... reactive oxygen species (ROS) The brain has minimal storage of energy sources, making it exceptionally sensitive to interruptions in its blood supply. It is not therefore surprising that the cerebral circulation is a highly specialized vascular bed with a number of unique physiological mechanisms...

... Biochemical Society 2010 atherosclerosis mitogen-activated protein kinase (MAPK) reactive oxygen species (ROS) resistin smooth muscle cell signal transducer and activator of transcription (STAT) stretch Resistin is an adipocytokine and has been shown to have potent pro-inflammatory...

... endothelial vascular cell exercise nitric oxide pancreatic β-cell reactive oxygen species (ROS) The beneficial effects of aerobic exercise of moderate intensity in T2DM (Type 2 diabetes mellitus) are well documented with regard to glycaemic control and multiple CVD (cardiovascular disease) risk...

.... Correspondence: Professor Cuihua Zhang (email [email protected] ). 3 6 2008 22 7 2008 12 8 2008 inflammation macrovascular circulation microvascular circulation nitric oxide reactive oxygen species (ROS) tumour necrosis factor-α (TNF-α) IHD (ischaemic heart disease...

... 2008 antioxidant ischaemia/reperfusion liver oxidative stress Pringle manoeuvre reactive oxygen species (ROS) Blood was collected into EDTA-containing tubes (Vacutainer; Becton Dickinson). All blood samples were immediately put on ice, and kept on ice during sample...

... phosphoinositide 3-kinase (PI3K) reactive oxygen species (ROS) There is evidence that a diet rich in vegetables and fruit has a beneficial effect on blood pressure. This effect has been attributed to phenolic compounds present in the plants. These compounds have also been shown to influence endothelial...

... p22 phox subunit reactive oxygen species (ROS) superoxide anion NADPH oxidase is sensitively regulated by a wide range of (patho)physiologically relevant factors, which include (i) humoral factors, (ii) mechanical factors, and (iii) genetic variants [ 9 , 42 ]. Humoral factors...

... cellular homoeostasis host defence NADPH oxidase pathogenesis phagocyte reactive oxygen species (ROS) superoxide anion ROS (reactive oxygen species) represent a diverse family of molecules that play roles in a myriad of physiological and pathophysiological events. ROS are comprised of highly...

... deoxycorticosterone acetate (DOCA) endothelin hypertension mitochondria NADPH oxidase reactive oxygen species (ROS) A major focus within the basic science community studying hypertension is related to the role of ROS (reactive oxygen species). The broad definition of ROS includes oxygen-containing species...

... parameters. N -acetylcysteine genetic hypertension nuclear factor κB (NF-κB) nitric oxide synthase reactive oxygen species (ROS) NO (nitric oxide) plays an important role in the maintenance of vascular tone, which affects the level of BP (blood pressure) [ 1 – 3 ]. In various models...

..., MO, U.S.A.). Sodium bicarbonate was purchased from Labsynth products (Diadema, SP, Brazil). Dihydroethidium was obtained from Molecular Probes (Eugene, OR, U.S.A.). linoleic acid oleic acid lymphocyte protein kinase C (PKC) reactive oxygen species (ROS) Generation of moderate...