.... Catalase has an inferior affinity for H 2 O 2 and is limited to peroxisomes [ 16 ]. antioxidants mitochondria pre-eclampsia reactive oxygen species (ROS) Pre-eclampsia is a multisystemic disorder of pregnancy, which affects more than eight million pregnancies worldwide annually...

... molecular mechanisms and signal pathways mediating the expression of leptin induced by cyclic mechanical stretch. angiotensin II cardiomyocyte hypertrophy extracellular signal-regulated kinase (ERK) leptin reactive oxygen species (ROS) transcriptional activity • Mechanical cyclic...

... © The Authors Journal compilation © 2013 Biochemical Society 2013 nitric oxide renin inhibition reactive oxygen species (ROS) small artery vascular remodelling • Aliskiren represents an antihypertensive agent with a new mechanism based on the inhibition of a catalytic activity...

... 10 2 2011 © The Authors Journal compilation © 2011 Biochemical Society 2011 atherosclerosis exercise inflammation myokine obesity reactive oxygen species (ROS) sedentary lifestyle Cardiovascular diseases remain the leading cause of death in modern societies. The dramatic...

...) and T-cells in the pathogenesis of vitiligo. immune system melanocyte reactive oxygen species (ROS) skin T-cell vitiligo © The Authors Journal compilation © 2011 Biochemical Society 2011 23 11 2009 26 8 2010 26 8 2010 Correspondence: Dr Steven J. Glassman...

... (NO • ) oxidative stress reactive oxygen species (ROS) The brain has minimal storage of energy sources, making it exceptionally sensitive to interruptions in its blood supply. It is not therefore surprising that the cerebral circulation is a highly specialized vascular bed with a number of unique...

... overload. Correspondence: Professor Kou-Gi Shyu (email [email protected] ). 17 3 2009 16 6 2009 17 7 2009 17 7 2009 © The Authors Journal compilation © 2010 Biochemical Society 2010 atherosclerosis mitogen-activated protein kinase (MAPK) reactive oxygen species...

...). Correspondence: Professor Philip Newsholme (email [email protected] ). 17 8 2009 6 10 2009 8 10 2009 © The Authors Journal compilation © 2010 Biochemical Society 2010 diabetes endothelial vascular cell exercise nitric oxide pancreatic β-cell reactive oxygen species (ROS...

... circulation nitric oxide reactive oxygen species (ROS) tumour necrosis factor-α (TNF-α) IHD (ischaemic heart disease) accounts for over 500000 deaths annually in the United States. AMI (acute myocardial infarction), also known as a heart attack [ 1 ], is a common complication of IHD. AMI usually...

... pathways of ischaemic preconditioning. antioxidant ischaemia/reperfusion liver oxidative stress Pringle manoeuvre reactive oxygen species (ROS) Correspondence: Dr Ger H. Koek (email [email protected] ). 7 9 2007 23 10 2007 9 11 2007 9 11 2007 © The Authors...

... endothelial nitric oxide synthase (eNOS) grape seed extract phosphoinositide 3-kinase (PI3K) reactive oxygen species (ROS) After equilibration for 60 min at a pre-load of 8 g, the aortic rings were pre-contracted with 10 μmol/l noradrenaline (norepinephrine; Sigma). Acetylcholine (Sigma) was added...

[email protected] ). 17 4 2007 8 6 2007 25 6 2007 © The Authors Journal compilation © 2008 Biochemical Society 2008 cardiovascular disease NADPH oxidase oxidative stress p22 phox subunit reactive oxygen species (ROS) superoxide anion Oxidative stress is defined...

... defence NADPH oxidase pathogenesis phagocyte reactive oxygen species (ROS) superoxide anion ROS (reactive oxygen species) represent a diverse family of molecules that play roles in a myriad of physiological and pathophysiological events. ROS are comprised of highly unstable and thus short...

... hypertension mitochondria NADPH oxidase reactive oxygen species (ROS) A major focus within the basic science community studying hypertension is related to the role of ROS (reactive oxygen species). The broad definition of ROS includes oxygen-containing species that are all capable of reacting...

... considered to differ significantly if the P value was <0.05. Linear regression analysis was used for evaluation of relationships between studied parameters. N -acetylcysteine genetic hypertension nuclear factor κB (NF-κB) nitric oxide synthase reactive oxygen species (ROS) BP...

... lymphocyte protein kinase C (PKC) reactive oxygen species (ROS) Generation of moderate amounts of ROS (reactive oxygen species) by several non-phagocytic leucocytes, including B-lymphocyte cell lines [ 1 – 4 ], human tonsillar B-lymphocytes [ 5 ], thymocytes [ 6 , 7 ], human NK (natural killer...