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Keywords: receptors
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Articles
Clin Sci (Lond) (2022) 136 (10): 799–802.
Published: 27 May 2022
...Colin Sumners; Igor Maciel Souza Silva; U. Muscha Steckelings This commentary on the article “Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptors” by Sanja Bosnyak et al. ( Clini. Sci. (Lond.) (2011) 121(7): 297–303. https://doi.org/10.1042/CS20110036 ) summarises...
Articles
Clin Sci (Lond) (2018) 132 (10): 1075–1083.
Published: 31 May 2018
...-density lipoprotein cholesterol IDL intermediate-density lipoprotein IS internal standard LC–MS/MS liquid chromatography–tandem mass spectrometry LDL-C low-density lipoprotein cholesterol LDLR low-density lipoprotein receptor Lp(a) lipoprotein (a) mAbs monoclonal...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2002) 103 (s2002): 141S–147S.
Published: 01 September 2002
...Ghassan BKAILY; Danie MASSAAD; Sanaa CHOUFANI; Danielle JACQUES; Pedro D'ORLÉANS-JUSTE Our previous work in heart cells showed that the nuclear envelope membranes possess receptors, such as those for angiotensin II. Using non-working single cells from the hearts of 10-day chick embryos...
Articles
Clin Sci (Lond) (2002) 103 (s2002): 430S–433S.
Published: 01 September 2002
... relaxatory responses of jejunal longitudinal muscle to tetrodotoxin-sensitive electrical field stimulation. Long-term treatment with a selective ET A-type receptor antagonist, markedly reduced hyperglycaemia and restored plasma glucose clearance rates towards normal. This was associated with a restoration...
Articles
Clin Sci (Lond) (2000) 99 (3): 175–179.
Published: 02 August 2000
...Daniel F. MCAULEY; Ailish G. NUGENT; Colm MCGURK; Suzanne MAGUIRE; J. Randal HAYES; G. Dennis JOHNSTON Endothelin-1 has potent vasoconstrictor and vasopressor actions contributing to basal vascular tone and maintenance of blood pressure acting predominantly through endothelin-A receptors...
Articles
Clin Sci (Lond) (2000) 98 (2): 217–240.
Published: 31 January 2000
... receptors that form part of the steroid/thyroid receptor superfamily. By examining the actions of all of these hormones in vivo and in vitro , this review gives a general overview of the current understanding of steroid hormone action in bone. In addition, a comprehensive review of steroid hormone receptor...
Articles
Clin Sci (Lond) (1996) 91 (2): 147–154.
Published: 01 August 1996
...Xiao C. Li; Robert E. Widdop 16 4 1996 16 4 1996 © 1996 The Biochemical Society and the Medical Research Society 1996 angiotensin II antagonists AT receptors CV-11974 EXP 3174 renal vasodilatation spontaneously hypertensive rats Clinical Science (1996) 91, 147-154...
Articles
Clin Sci (Lond) (1995) 89 (6): 575–579.
Published: 01 December 1995
...Paddy A. Phillips; John Risvanis; Kathryn Aldred; Louise M. Burrell; Briony Bartholomeusz 1. We studied the effects of the non-selective, non-peptide, orally active endothelin (ET) receptor antagonist bosentan (Ro 47–0203) on rat hepatic and mesenteric vascular membrane 125 I-ET-1 binding...
Articles
Clin Sci (Lond) (1995) 88 (6): 671–674.
Published: 01 June 1995
...Paddy A. Phillips; John Risvanis; Anne-Marie Hutchins; Louise M. Burrell; Duncan MacGregor; Andrew L Gundlach; Colin I. Johnston 1. To investigate the mechanism of hepatic V1a vasopressin receptor down-regulation in streptozotocin-induced diabetes mellitus in the rat, we measured hepatic V1a...
Articles
Clin Sci (Lond) (1992) 83 (2): 233–239.
Published: 01 August 1992
... tubule) insulin-like growth factor-I in the control of proximal nephron receptor density. In addition, we studied the factors that influence liver insulin-like growth factor-I secretion in partially nephrectomized rats. 2. Dietary protein restriction (6% versus 40%) lowered circulating levels of insulin...
Articles
Clin Sci (Lond) (1991) 80 (2): 143–147.
Published: 01 February 1991
.... There were no differences between control and cirrhotic rats in the affinity of angiotensin II for its glomerular receptors. However, the angiotensin II receptor density was higher in cirrhotic than in control rats, thereby producing an increased total angiotensin II binding in cirrhotic rats. 6. Since...
Articles
Clin Sci (Lond) (1991) 80 (2): 101–105.
Published: 01 February 1991
...Pietro Amedeo Modesti; Rosanna Abbate; Gian Franco Gensini; Andrea Colella; Gian Gastone Neri Serneri 1. Human platelet thromboxane A 2 receptor expression on the membrane surface is possibly dynamically regulated by changes either in the ligand concentration or in membrane fluidity. An increased...
Articles
Clin Sci (Lond) (1987) 72 (5): 593–598.
Published: 01 May 1987
... in the pathogenesis of coeliac disease. 5 11 1986 27 11 1986 © 1970 The Biochemical Society and the Medical Research Society 1970 coeliac disease enterocyte gliadin lectin receptors ClinicalScience( 1987) 12, 593-598 593 Gliadin binding to rat and human enterocytes J. COLYER, P. J. KUMAR...
Articles
Clin Sci (Lond) (1985) 68 (3): 357–364.
Published: 01 March 1985
...J. S. D. Scott; E. P. W. Bowman; W. G. E. Cooksley 1. Binding of cobalamin (Cbl) was compared in liver and kidney plasma membranes prepared from rat and human tissues. 2. Single, high-affinity, saturable (200 pmol/l), binding sites for TC II-Cbl were found in all tissues; by contrast no receptors...
Articles
Clin Sci (Lond) (1983) 65 (1): 95–98.
Published: 01 July 1983
...C. Cortese; P. R. Turner; C. B. Marenah; U. Sule; S. Price; N. E. Miller; B. Lewis 1. Measurements were made of the maximal low-density lipoprotein (LDL) receptor activities of blood lymphocytes from 81 healthy men with a wide range of plasma LDL cholesterol concentrations (1.45-7.55 mmol/l). 2...
Articles
Clin Sci (Lond) (1982) 62 (4): 381–387.
Published: 01 April 1982
... hyperparathyroidism associated with vitamin D deficiency. 10 8 1981 26 10 1981 © 1982 The Biochemical Society and the Medical Research Society 1982 adenosine 3′:5′-cyclic monophosphate hyperparathyroidism (secondary) kidney parathyroid hormone receptors vitamin D deficiency Clinical...
Articles
Clin Sci (Lond) (1982) 62 (4): 397–401.
Published: 01 April 1982
...M. Weight; C. Cortese; U. Sule N. E. Miller; B. Lewis 1. The concordance of low density lipoprotein (LDL) receptor activity of blood mononuclear cells was examined in 26 pairs of monozygotic and 17 pairs of dizygotic normolipidaemic young adult male twins. 2. Receptor activity was quantified...
Articles
Clin Sci Mol Med (1976) 51 (s3): 315s–317s.
Published: 01 December 1976
.... This enhanced response to aldosterone required the presence of the adrenal glands during the induction period, could be suppressed by a high sodium intake, but could not be induced by a low sodium diet. 3. No difference between high K + and control rats could be detected in renal mineralocorticoid receptors...
Articles
Clin Sci Mol Med (1976) 51 (s3): 321s–324s.
Published: 01 December 1976
...J. D. Baxter; M. Schambelan; D. T. Matulich; B. J. Spindler; F. C. Bartter 1. A competitive ‘mineralocorticoid’ receptor-binding technique has been used to study plasma ‘mineralocorticoid’ activity in normal and hypertensive states. The binding reaction mixture contains the competitor steroids...
Articles
Clin Sci Mol Med (1976) 51 (1): 41–45.
Published: 01 July 1976
... activity of Sar 1 -angiotensin II. 4. These results suggest functional differences in receptors for angiotensin II in vascular smooth muscle and in adrenal cortex. aldosterone angiotensin II antagonist blood pressure receptors 21 11 1975 © 1976 The Biochemical Society and the Medical...
Articles
Clin Sci Mol Med (1974) 46 (1): 143–147.
Published: 01 January 1974
...P. B. Greenberg; Carmel J. Hillyard; Leonora S. Galante; Kay W. Colston; Imogen M. A. Evans; I. MacIntyre 1. The affinity of cholecalciferol, ergocalciferol and 25-hydroxyergocalciferol for 25-hydroxycholecalciferol receptors in human, rat and chicken kidney cytosol fractions is related...