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Keywords: renal blood flow
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Articles
Clin Sci (Lond) (2018) 132 (13): 1453–1470.
Published: 18 July 2018
... increased cortical renal blood flow in Uchl1 -/- mice, suggesting that hyperfiltration results from afferent arteriole dilation. Nonetheless, hyperglycemia, cyclooxygenase-2, and nitric oxide synthases were ruled out as sources of hyperfiltration in Uchl1 -/- mice as glomerular filtration rate remained...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2005) 109 (3): 311–317.
Published: 24 August 2005
... pretreatment with 150 mg of irbesartan once a day for 5 consecutive days. RPF (renal plasma flow) and GFR (glomerular filtration rate) were also measured. Before Ang II infusion, the PFH and NFH groups did not differ with respect to BP (blood pressure), body mass index, PRA, RBF (renal blood flow) or urinary...
Articles
Clin Sci (Lond) (2002) 103 (s2002): 245S–248S.
Published: 01 September 2002
... ET-1 in normal rats and in rats with experimental congestive heart failure (CHF) produced by aortocaval fistula. Intravenous injection of ET-1 (1.0nmol·kg -1 of body weight) to anaesthetized normal rats produced sustained decreases in renal blood flow (RBF) (assessed by ultrasonic flowmetry) and...
Articles
Clin Sci (Lond) (1998) 95 (6): 693–699.
Published: 01 December 1998
...Nadine MAYBAUM; Elena GORODETSKY; Marta WEINSTOCK 1. We have previously shown that normotensive rabbits with a genetic impairment in arterial baroreflex sensitivity showed a delayed sodium excretion and failed to increase their renal blood flow in response to a saline infusion that did not alter...
Articles
Clin Sci (Lond) (1997) 92 (5): 433–443.
Published: 01 May 1997
...Kevin Moore 1. The hepatorenal syndrome is the development of renal failure in patients with severe liver disease in the absence of any identifiable renal pathology. 2. Decreased glomerular filtration is caused by a reduction in both renal blood flow and the renal filtration fraction. These changes...
Articles
Clin Sci (Lond) (1994) 87 (2): 143–149.
Published: 01 August 1994
...Anders Edlund; Hans Ohlsén; Alf Sollevi 1. The effects of local intra-arterial infusion of adenosine on renal blood flow, glomerular filtration and renin release in eight healthy awake subjects have been examined. 2. Renal blood flow and glomerular filtration rate were measured as the clearances of...
Articles
Clin Sci (Lond) (1991) 81 (6): 727–732.
Published: 01 December 1991
.... 2. Mean arterial blood pressure, heart rate and cardiac output were not changed significantly by l -arginine infusion. However, l -arginine infusion induced a significant elevation of renal blood flow from 50 ± 3 to 94 ± 12 ml/min (means ± sem , P < 0.01). 3. Simultaneous infusion of N G...
Articles
Clin Sci (Lond) (1991) 80 (2): 131–136.
Published: 01 February 1991
... protein excretion. 2. In patients with chronic glomerulonephritis, dopamine infusion significantly increased urinary sodium excretion (+ 59%), renal blood flow (+ 20%) and creatinine clearance (+ 14%). However, urinary protein excretion was not changed. Addition of atrial natriuretic peptide to the...
Articles
Clin Sci (Lond) (1990) 79 (6): 551–558.
Published: 01 December 1990
... antagonists BN-52021 (1 mg/kg, intraperitoneally) and alprazolam (1 and 5 mg/kg, intraperitoneally) on the evolution of glomerular filtration and renal blood flow, in the experimental model of acute renal failure induced by the intramuscular injection of glycerol in rats. 2. We have also measured...
Articles
Clin Sci (Lond) (1990) 78 (2): 165–168.
Published: 01 February 1990
... pressure, glomerular filtration rate, renal blood flow or urinary sodium excretion, in rats on sodium restriction. It did not change mean blood pressure, glomerular filtration rate or urinary sodium excretion, but decreased renal blood flow, in rats on a normal sodium intake. 4. The kallikrein–kinin system...
Articles
Clin Sci (Lond) (1989) 77 (5): 567–572.
Published: 01 November 1989
.... In contrast with the various changes in systemic haemodynamics, renal blood flow transiently increased immediately after bolus injection in a dose-dependent manner (28%, P < 0.05, 50%, P < 0.01 and 110%, P < 0.01 with 4, 40 and 200 pmol of endothelin/kg, respectively). This transient...
Articles
Clin Sci (Lond) (1989) 77 (1): 55–60.
Published: 01 July 1989
...Wilbert M. T. Janssen; Dick de Zeeuw; Gjalt K. van der Hem; Paul E. de Jong 1. We studied the effect of a low-dose infusion of atrial natriuretic peptide (ANP) on renal blood flow in healthy volunteers. We additionally investigated the effect of ANP on renal haemodynamic function and on urinary...
Articles
Clin Sci (Lond) (1988) 74 (1): 11–15.
Published: 01 January 1988
...Bernardo Rodríguez-Iturbe; Josē Herrera; Rafael García 1. We studied the relationship between changes in glomerular filtration rate (GFR) determined as inulin clearance (C In ), and changes in renal blood flow (RBF), determined as p -aminohippurate clearance (C PAH ), after the ingestion of a large...
Articles
Clin Sci (Lond) (1988) 74 (1): 63–69.
Published: 01 January 1988
...S. B. Harrap; A. E. Doyle 1. To determine the relevance of renal circulatory abnormalities found in the immature spontaneously hypertensive rat (SHR) to the genetic hypertensive process, glomerular filtration rate and renal blood flow were measured in conscious F 2 rats, derived from crossbreeding...
Articles
Clin Sci (Lond) (1987) 72 (6): 657–667.
Published: 01 June 1987
... control period, during CEI (teprotide, 3 mg h −1 kg −1 ) infusion and during a third period of verapamil (600 μg h −1 kg −1 ) infusion superimposed on CEI infusion. 2. Although systemic blood pressure (BP) decreased from 175 ± 4 to 149 ± 5 mmHg (mean ± SEM) in response to verapamil alone, renal blood flow...
Articles
Clin Sci (Lond) (1987) 72 (4): 429–436.
Published: 01 April 1987
...Margrethe E. Olsen; John E. Hall; Jean-Pierre Montani; John E. Cornell 9 7 1986 24 10 1986 © 1970 The Biochemical Society and the Medical Research Society 1970 angiotensin II autoregulation glomerular filtration rate prostaglandins renal blood flow tubuloglomerular...
Articles
Clin Sci (Lond) (1986) 71 (3): 323–325.
Published: 01 September 1986
... specific for renal and mesenteric territories. 5 3 1986 11 4 1986 © 1986 The Biochemical Society and the Medical Research Society 1986 atrial natriuretic peptide cardiac output microspheres renal blood flow renal vascular bed total peripheral resistance Clinical Science(l986...
Articles
Clin Sci (Lond) (1986) 70 (3): 243–247.
Published: 01 March 1986
... prostaglandin E 2 renal blood flow renin sulindac Clinical Science (1986) 70, 243-241 243 Chronic effects of oral sulindac on renal haemodynamics and hormones in subjects with chronic renal disease CHARLES P. SWAINSON, PETER GRIFFITHS A N D MICHAEL L. WATSON Department of Medicine, Christchurch Clinical...
Articles
Clin Sci (Lond) (1983) 65 (5): 533–538.
Published: 01 November 1983
... neither renal blood flow nor glomerular filtration rate responses to decreasing renal perfusion pressure. 3. Hypercapnic acidosis ( P co 2 71 ±2 mmHg; pH 7.03 ± 0.01) significantly decreased both renal blood flow and glomerular filtration rate as renal perfusion pressure was lowered. This effect of...
Articles
Clin Sci (Lond) (1983) 65 (1): 47–55.
Published: 01 July 1983
... water-deprived rats. 3. Glomerular filtration rate and renal blood flow were not affected by atrial extract, indicating that the atrial natriuretic factor (ANF) directly inhibited sodium reabsorption at the tubular level. 4. Distal tubular blockade with a combination of frusemide and amiloride was...
Articles
Clin Sci (Lond) (1982) 62 (6): 573–579.
Published: 01 June 1982
... blood pressure from 164 ± 4 to 124 ± 4 mmHg. Despite the profound fall of arterial pressure, significant increases in renal blood flow from 5.82 ± 0.22 to 9.15 ± 0.76 ml/min and glomerular filtration rate from 1.46 ± 0.10 to 2.18 ± 0.14 ml/min were observed in the non-clipped kidneys. Renal vascular...
Articles
Clin Sci (Lond) (1981) 61 (6): 663–670.
Published: 01 December 1981
... increase in total peripheral resistance was due to vasoconstriction of nonrenal beds. 20 3 1981 1 5 1981 © 1981 The Biochemical Society and the Medical Research Society 1981 cardiac output Goldblatt hypertension renal blood flow renin Clinical Science (1981) 61,663-670 663...
Articles
Clin Sci (Lond) (1981) 61 (5): 553–557.
Published: 01 November 1981
...P. C. Wong; B. G. Zimmerman 1. Successive infusions of SQ 20 881 given intra-arterially (i.a.) to the kidney at 0.4 and 0.8 μg min −1 kg −1 for 50 min each did not alter renal blood flow and renal vascular resistance in spite of 40–47% blockade of the angiotensin I (ANG I i.a.)-induced...
Articles
Clin Sci (Lond) (1980) 59 (s6): 87s–90s.
Published: 01 December 1980
... blood pressure converting enzyme inhibition glomerular filtration rate renal blood flow sodium excretion Clinical Science (1980) 59,87~-90s 87s Long-term regulation of arterial pressure, glomerular filtration and renal sodium reabsorption by angiotensin I1 in dogs J . E. H A L L , A . C . G U Y T...
Articles
Clin Sci (Lond) (1980) 59 (s6): 381s–384s.
Published: 01 December 1980
... blood pressure. 2. At their respective spontaneous blood pressures, renal vascular resistance was higher and glomerular filtration rate (GFR) and renal blood flow were not different in the contralateral kidneys of the hypertensive rats (170 ± 5 mmHg) compared with normal animals (129 ± 1 mmHg). Urine...
Articles
Clin Sci (Lond) (1980) 59 (s6): 477s–478s.
Published: 01 December 1980
... found. 5. The results indicate that sympathetic activity may be an important determinant of renal blood flow in hypertension. The effectiveness of propranolol seems to depend upon a reduction in α-adrenergic tone. © 1980 The Biochemical Society and the Medical Research Society 1980 noradrenaline...
Articles
Clin Sci (Lond) (1979) 57 (s5): 421s–423s.
Published: 01 December 1979
... the Medical Research Society 1979 captopril essential hypertension renal blood flow renin CIinicalScience (1979) 51.421s-423~ Effect of captopril on renal vascular tone in patients with essential hypertension A. MIMRAN, H. R. B R U N N E R , G . A. T U R I N I , B. WAEBER AND D. BRUNNER...
Articles
Clin Sci Mol Med (1978) 55 (4): 335–339.
Published: 01 October 1978
... produced an increase in GFR not dependent on an increase in whole-kidney plasma flow. 20 12 1977 8 5 1978 © 1978 The Biochemical Society and the Medical Research Society 1978 glomerular filtration rate prolactin renal blood flow Clinical Science and Molecular Medicine (1978...
Articles
Clin Sci Mol Med (1977) 52 (5): 545–548.
Published: 01 May 1977
... intrarenal effects which lead to salt and water retention. 19 1 1977 7 2 1977 © 1977 The Biochemical Society and the Medical Research Society 1977 angiotensin II antagonist electrolyte excretion glomerular filtration rate renal blood flow Clinical Science and Molecular Medicine...
Articles
Clin Sci Mol Med (1976) 51 (s3): 641s–643s.
Published: 01 December 1976
...) were investigated in twelve patients with essential hypertension. 2. The anti-hypertensive action of both compounds was similar and was accompanied by a reduction in heart rate and in cardiac output, total peripheral resistance being unchanged. There was no alteration in renal blood flow and glomerular...
Articles
Clin Sci Mol Med (1976) 51 (s3): 373s–375s.
Published: 01 December 1976
... only when the sino-aortic reflexes are intact. © 1976 The Biochemical Society and the Medical Research Society 1976 arterial pressure carotid sinus mesenteric blood flow muscle blood flow renal blood flow sympathetic nervous system Clinical Science and Molecular Medicine (1976) 51, 3739...
Articles
Clin Sci Mol Med (1976) 51 (s3): 605s–607s.
Published: 01 December 1976
...A. Wester; G. A. Zaal; P. W. De Leeuw; W. H. Birkenhäger 1. In eighteen subjects with mild to moderate hypertension the effectiveness of the new vasodilator drug L6150 (Lepetit) was studied. Its mechanism of action was identified by systemic and renal blood flow measurements and by estimating...
Articles
Clin Sci Mol Med (1976) 51 (6): 583–588.
Published: 01 December 1976
...W. R. Withey; B. J. Chapman; K. A. Munday 1. Renal function was measured in seven normo thermic (38°C) and seven hypothermic (27°C) dogs. 2. The glomerular filtration rate was 60% lower in the hypothermic animals, and the renal blood flow was 51% lower. The intrarenal distribution of blood flow was...
Articles
Clin Sci Mol Med (1976) 50 (3): 177–184.
Published: 01 March 1976
...J. Yudkin; R. D. Cohen; Barbara Slack 1. The effect of metabolic acidosis of 4–6 h duration on cardiac output, blood pressure, heart rate, and hepatic and renal blood flow has been studied in the rat. 2. In anaesthetized rats, blood pressure and heart rate fell linearly with blood pH in both sham...
Articles
Clin Sci Mol Med (1975) 48 (6): 533–535.
Published: 01 June 1975
...D. J. Warren; J. G. G. Ledingham 1. The effect of propranolol on total and regional renal blood flow was measured in conscious rabbits after 6 days on normal or low sodium diets. 2. Propranolol inhibited the fall in total superficial cortical renal blood flow which occurred in response to the low...
Articles
Clin Sci Mol Med (1975) 48 (1): 51–60.
Published: 01 January 1975
...D. J. Warren; J. G. G. Ledingham 1. Total renal blood flow and its distribution within the renal cortex of the conscious rabbit were studied with radioactive microspheres of 15 and 25 μm diameter. 2. The reliability of the microsphere technique was influenced by microsphere diameter and number...
Articles
Clin Sci Mol Med (1975) 48 (s2): 299s–302s.
Published: 01 January 1975
... of the renin-angiotensin system. 3. Indomethacin induced a decrease in renal blood flow. 4. Angiotensin receptor blockade with Sar 1 -Ala 8 -angiotensin II blunted the blood pressure effect and prevented the renal haemodynamic changes induced by indomethacin. © 1975 The Biochemical Society and the...
Articles
Clin Sci Mol Med (1973) 45 (s1): 243s–246s.
Published: 01 August 1973
... contralateral denervated kidney. Renal blood flow markedly decreases in the innervated, and remains unchanged in the denervated, kidney during pontine stimulation. 2. Blockade of the vasomotor response to pontine stimulation in one kidney by close arterial infusion of phenoxybenzamine does not reduce the renin...
Articles
Clin Sci (1972) 43 (3): 401–411.
Published: 01 September 1972
... indicator-dilution technique. 2. Increases in renal blood flow during graded intravenous iso-osmotic saline or hyperosmotic mannitol infusions and during renal arterial infusions of acetylcholine or prostaglandin E 1 were consistently associated with reduced E PAH . 3. The cortical fraction of renal blood...
Articles
Clin Sci (1972) 42 (5): 627–634.
Published: 01 May 1972
...D. C. Fluck; T. R. Evans; D. C. Siggers; J. Crawley; S. A. Srivongse 1. The renal blood flow distribution has been studied by the Xe washout method in nineteen patients undergoing routine left-sided cardiac catheterization. 2. It was found that there were two separate groups, one in which the...