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Articles

First identification of PODXL nonsense mutations in autosomal dominant focal segmental glomerulosclerosis

Fu-Jun Lin, Lei Yao, Xue-Qing Hu, Fan Bian, Gang Ji, Geng-Ru Jiang, Daniel P. Gale, Hong-Qi Ren

Clin Sci (Lond) (2019) 133 (1): 9–21.

https://doi.org/10.1042/CS20180676

Published: 03 January 2019

... of the affected patients in the pedigree is presented in Table 1 . focal segmental glomerulosclerosis genetic kidney disease podocyte proteinuria renal failure Podocytes are terminally differentiated pericyte-like cells with a complex architecture that have an important role in the structure...

View articletitled, First identification of PODXL nonsense mutations in autosomal dominant focal segmental glomerulosclerosis

Includes: Supplementary data

Articles

Skeletal muscle morphology and capillarization of renal failure patients receiving different dialysis therapies

Giorgos K. SAKKAS, Derek BALL, Anthony J. SARGEANT, Thomas H. MERCER, Pelagia KOUFAKI, Patrick F. NAISH

Clin Sci (Lond) (2004) 107 (6): 617–623.

https://doi.org/10.1042/CS20030282

Published: 24 November 2004

...Giorgos K. SAKKAS; Derek BALL; Anthony J. SARGEANT; Thomas H. MERCER; Pelagia KOUFAKI; Patrick F. NAISH The morphology of gastrocnemius muscles was examined in RFPs (renal failure patients) being treated using HD (haemodialysis) and CAPD (continuous ambulatory peritoneal dialysis). RFPs ( n =24...

View articletitled, Skeletal muscle morphology and capillarization of renal failure patients receiving different dialysis therapies

Articles

Beneficial effect of β-adrenergic blockade on left ventricular function in haemodialysis patients

Yuji HARA, Mareomi HAMADA, Yuji SHIGEMATSU, Bonpei MURAKAMI, Kunio HIWADA

Clin Sci (Lond) (2001) 101 (3): 219–225.

https://doi.org/10.1042/cs1010219

Published: 03 August 2001

... 2001 12 3 2001 27 4 2001 The Biochemical Society and the Medical Research Society © 2001 2001 -blocker dilated left ventricle haemodialysis natriuretic peptides renal failure 219Clinical Science (2001) 101, 219 225 (Printed in Great Britain) Beneficial effect of b...

View articletitled, Beneficial effect of β-adrenergic blockade on left ventricular function in haemodialysis patients

Articles

The effect of different methods of storage on the results of serum total CO2 assays

Matthew L. P. HOWSE, Maureen LEONARD, Michael VENNING, Laurence SOLOMAN

Clin Sci (Lond) (2001) 100 (6): 609–611.

https://doi.org/10.1042/cs1000609

Published: 25 April 2001

...Matthew L. P. HOWSE; Maureen LEONARD; Michael VENNING; Laurence SOLOMAN Metabolic acidosis frequently complicates end-stage renal failure. In haemodialysis patients its severity is usually monitored by measurement of the total CO 2 (TCO 2 ) level. Samples from ‘satellite dialysis’ patients...

View articletitled, The effect of different methods of storage on the results of serum total CO2 assays

Articles

Non-steroidal anti-inflammatory drugs and renal response to exercise: a comparison of indomethacin and nabumetone

Niels Vidiendal OLSEN, Niels Georg JENSEN, Jesper Melchior HANSEN, Niels Juel CHRISTENSEN, Niels FOGH-ANDERSEN, Inge-Lis KANSTRUP

Clin Sci (Lond) (1999) 97 (4): 457–465.

https://doi.org/10.1042/cs0970457

Published: 24 August 1999

... by blockade of vasodilatory prostaglandins. Key words : cyclo-oxygenase, exercise, indomethacin, kidney, nabumetone, non-steroidal anti-inflammatory drugs, prostaglandins, renal failure, renal haemodynamics, renin, sodium excretion. Abbreviations : ANOVA, analysis of variance ; C Na , sodium clearance ; DTPA...

View articletitled, Non-steroidal anti-inflammatory drugs and renal response to exercise: a comparison of indomethacin and nabumetone

Articles

Elevated Plasma Levels of Human Adrenomedullin in Cardiovascular, Respiratory, Hepatic and Renal Disorders

Bernard Cheung, Raymond Leung

Clin Sci (Lond) (1997) 92 (1): 59–62.

https://doi.org/10.1042/cs0920059

Published: 01 January 1997

... with essential hypertension, 12 with heart failure, 10 with ascites due to cirrhosis, 12 with chronic renal failure, four with hypoxia due to chronic obstructive pulmonary disease and 12 control subjects. 3. Plasma levels (mean ± SEM) in patients with essential hypertension (16.3 ± 1.9 pmol/l), congestive heart...

View articletitled, Elevated Plasma Levels of Human Adrenomedullin in Cardiovascular, Respiratory, Hepatic and Renal Disorders

Articles

Human Erythrocyte Choline Uptake in Uraemia: The Role of Intracellular Substrate and An Investigation into the Effects of Haemodialysis

G. J. Flanagan, J. O'kelly, C. Rae, C. G. Winearls, J. C. Ellory

Clin Sci (Lond) (1996) 91 (3): 353–358.

https://doi.org/10.1042/cs0910353

Published: 01 September 1996

... in vitro washing there is a fall in V max , and no longer any significant difference between pre- and post-dialysis samples. There remains a significant difference in the erythrocyte choline V max between samples from patients with chronic renal failure and from normal subjects ( P < 0.005). 4. Human...

View articletitled, Human Erythrocyte Choline Uptake in Uraemia: The Role of Intracellular Substrate and An Investigation into the Effects of Haemodialysis

Articles

Elevated Plasma C-Type Natriuretic Peptide Concentrations in Patients with Chronic Renal Failure

Kazuhito Totsune, Kazuhiro Takahashi, Osamu Murakami, Fumitoshi Satoh, Masahiko Sone, Toraichi Mouri

Clin Sci (Lond) (1994) 87 (3): 319–322.

https://doi.org/10.1042/cs0870319

Published: 01 September 1994

... diseases have not yet been studied. 2. Plasma immunoreactive C-type natriuretic peptide concentrations were studied by radioimmunoassay in normal subjects, patients with congestive heart failure, non-dialysed patients with chronic renal failure and haemodialysis patients with chronic renal failure. The C...

View articletitled, Elevated Plasma C-Type Natriuretic Peptide Concentrations in Patients with Chronic Renal Failure

Articles

Effects of Vasopressin V 1 and V 2 Receptor Antagonists on Progressive Renal Failure in Rats

Hirokazu Okada, Hiromichi Suzuki, Yoshihiko Kanno, Yoshitaka Yamamura, Takao Saruta

Clin Sci (Lond) (1994) 86 (4): 399–404.

https://doi.org/10.1042/cs0860399

Published: 01 April 1994

...Hirokazu Okada; Hiromichi Suzuki; Yoshihiko Kanno; Yoshitaka Yamamura; Takao Saruta 1. The relationship between vasopressin and the progression of renal failure has been proposed, but not intensively investigated because of a lack of orally available, selective vasopressin antagonists. 2...

View articletitled, Effects of Vasopressin V 1 and V 2 Receptor Antagonists on Progressive Renal Failure in Rats

Articles

Dopamine β -Hydroxylase Immunoreactivity in Human Cerebrospinal Fluid: Properties, Relationship to Central Noradrenergic Neuronal Activity and Variation in Parkinson's Disease and Congenital Dopamine β -Hydroxylase Deficiency

Daniel T. O'Connor, Justine H. Cervenka, Richard A. Stone, Gail L. Levine, Robert J. Parmer, Rebecca E. Franco-Bourland, Ignacio Madrazo, Philip J. Langlais, David Robertson, Italo Biaggioni

Clin Sci (Lond) (1994) 86 (2): 149–158.

https://doi.org/10.1042/cs0860149

Published: 01 February 1994

... in disease states such as hypertension, renal failure, Parkinsonism and congenital dopamine β-hydroxylase deficiency. 2. Authentic, physically stable dopamine β-hydroxylase immunoreactivity was present in normal human cerebrospinal fluid at a concentration of 31.3 ± 1.4 ng/ml (range: 18.5–52.5 ng/ml...

View articletitled, Dopamine β -Hydroxylase Immunoreactivity in Human Cerebrospinal Fluid: Properties, Relationship to Central Noradrenergic Neuronal Activity and Variation in Parkinson's Disease and Congenital Dopamine β -Hydroxylase Deficiency

Articles

Changes in Renal Function in Acute Experimental Pancreatitis in Rats: A Therapeutic Role for Somatostatin

M. González-Rubio, C. García-Escribano, M. L. Díez-Marqués, I. Arribas, P. Martínez-Onsurbe, M. Rodríguez-Puyol, D. Rodríguez-Puyol

Clin Sci (Lond) (1993) 85 (5): 615–621.

https://doi.org/10.1042/cs0850615

Published: 01 November 1993

... in a large number of patients [l]. Acute renal failure sometimes appears in patients with pancreatitis [2]. Although the incidence of this complication changes in the different series, ranging between 1 and 6% [3], the mortality rate in acute pancreatitis when renal failure occurs is so high that renal...

View articletitled, Changes in Renal Function in Acute Experimental Pancreatitis in Rats: A Therapeutic Role for Somatostatin

Articles

Plasma concentrations and comparisons of brain natriuretic peptide and atrial natriuretic peptide in normal subjects, cardiac transplant recipients and patients with dialysis-independent or dialysis-dependent chronic renal failure

M. G. Buckley, D. Sethi, N. D. Markandu, G. A. Sagnella, D. R. J. Singer, G. A. MacGregor

Clin Sci (Lond) (1992) 83 (4): 437–444.

https://doi.org/10.1042/cs0830437

Published: 01 October 1992

... (18.8 ± 3.9 pmol/l, n = 12) and in patients with dialysis-independent (8.8 ± 1.5 pmol/l, n = 11) or dialysis-dependent (41.6 ± 8.8 pmol/l, n = 14) chronic renal failure. Similarly, in these groups of patients plasma levels of atrial natriuretic peptide were also significantly raised when compared...

View articletitled, Plasma concentrations and comparisons of brain natriuretic peptide and atrial natriuretic peptide in normal subjects, cardiac transplant recipients and patients with dialysis-independent or dialysis-dependent chronic renal failure

Articles

Platelets from patients on haemodialysis show impaired responses to nitric oxide

M. P. Gordge, G. H. Neild

Clin Sci (Lond) (1992) 83 (3): 313–318.

https://doi.org/10.1042/cs0830313

Published: 01 September 1992

... was receiving nitrates, and no other drugs known to influence platelet function were being taken. The study was approved by the Ethics Committee of the Institute of Urology, and informed consent was obtained from each subject. Key words: haemodialysis. guanylate cyclase, nitric oxide, platelets, renal failure...

View articletitled, Platelets from patients on haemodialysis show impaired responses to nitric oxide

Articles

Orotidine Accumulation in Human Erythrocytes during Allopurinol Therapy: Association with High Urinary Oxypurinol-7-Riboside Concentrations in Renal Failure and in the Lesch-Nyhan Syndrome

H. A. Simmonds, S. Reiter, P. M. Davies, J. S. Cameron

Clin Sci (Lond) (1991) 80 (3): 191–197.

https://doi.org/10.1042/cs0800191

Published: 01 March 1991

...H. A. Simmonds; S. Reiter; P. M. Davies; J. S. Cameron 1. A compound identified as orotidine has been found in the erythrocytes of all subjects on allopurinol. 2. The erythrocyte orotidine concentrations were much higher in patients with renal failure or with the Lesch-Nyhan syndrome. 3...

View articletitled, Orotidine Accumulation in Human Erythrocytes during Allopurinol Therapy: Association with High Urinary Oxypurinol-7-Riboside Concentrations in Renal Failure and in the Lesch-Nyhan Syndrome

Articles

Cardiac output and oxygen uptake in patients with renal failure

C. H. Kong, F. D. Thompson, F. J. Imms

Clin Sci (Lond) (1990) 78 (6): 591–596.

https://doi.org/10.1042/cs0780591

Published: 01 June 1990

...C. H. Kong; F. D. Thompson; F. J. Imms 1. Cardiac index, oxygen uptake and haemoglobin concentration have been measured in eight patients with end-stage renal failure, and the values compared with those in eight healthy control subjects. Assuming the arterial blood to be 97% saturated, the oxygen...

View articletitled, Cardiac output and oxygen uptake in patients with renal failure

Articles

Immunoreactive N -terminal Pro-Atrial Natriuretic Peptide in Human Plasma: Plasma Levels and Comparisons with α-Human Atrial Natriuretic Peptide in Normal Subjects, Patients with Essential Hypertension, Cardiac Transplant and Chronic Renal Failure

M. G. Buckley, G. A. Sagnella, N. D. Markandu, D. R. J. Singer, G. A. MacGregor

Clin Sci (Lond) (1989) 77 (5): 573–579.

https://doi.org/10.1042/cs0770573

Published: 01 November 1989

..., seven patients with dialysis-independent chronic renal failure and 11 patients with haemodialysis-dependent chronic renal failure. Plasma was extracted on Sep-Pak cartridges and N -terminal ANP immunoreactivity was measured using an antibody directed against pro-ANP (1–30). 2. Plasma levels of TV...

View articletitled, Immunoreactive N -terminal Pro-Atrial Natriuretic Peptide in Human Plasma: Plasma Levels and Comparisons with α-Human Atrial Natriuretic Peptide in Normal Subjects, Patients with Essential Hypertension, Cardiac Transplant and Chronic Renal Failure

Articles

Protective Effect of p -Chlorophenylalanine in Glycerol-Induced Acute Renal Failure in Rats

Richard J. Barrett, David R. Taylor, Kathryn F. Wright

Clin Sci (Lond) (1989) 77 (2): 145–147.

https://doi.org/10.1042/cs0770145

Published: 01 August 1989

...Richard J. Barrett; David R. Taylor; Kathryn F. Wright 1. Studies were conducted to test the hypothesis that glycerol-induced acute renal failure in rats may be mediated by 5-hydroxytryptamine. 2. The tryptophan hydroxylase inhibitor, β-chlorophenylalanine, or saline was administered for 4 days...

View articletitled, Protective Effect of p -Chlorophenylalanine in Glycerol-Induced Acute Renal Failure in Rats

Articles

Influence of hyperinsulinaemia on intracellular amino acid levels and amino acid exchange across splanchnic and leg tissues in uraemia

Anders Alvestrand, Ralph A. Defronzo, Douglas Smith, John Wahren

Clin Sci (Lond) (1988) 74 (2): 155–163.

https://doi.org/10.1042/cs0740155

Published: 01 February 1988

... Research Society 1970 leg (muscle) tissue renal failure splanchnic tissues uraemia Clinical Science (1988) 74,155-163 155 Influence of hyperinsulinaemia on intracellular amino acid levels and amino acid exchange across splanchnic and leg tissues in uraemia ANDERS ALVESTRAND, RALPH A. DEFRONZO...

View articletitled, Influence of hyperinsulinaemia on intracellular amino acid levels and amino acid exchange across splanchnic and leg tissues in uraemia

Articles

Effect of different levels of protein intake on renal deterioration and nutritional state in experimental renal disease

Seiya Okuda, Kenichi Motomura, Tohru Sanai, Hideki Hirakata, Fumio Nanishi, Kaotu Onoyama, Masatoshi Fujishima

Clin Sci (Lond) (1987) 73 (1): 33–39.

https://doi.org/10.1042/cs0730033

Published: 01 July 1987

... nephrotic syndrome nutrition protein restriction renal failure ...

View articletitled, Effect of different levels of protein intake on renal deterioration and nutritional state in experimental renal disease

Articles

Extrarenal synthesis of 1,25-dihydroxyvitamin D: Sensitivity to glucocorticoid treatment

Silvano Adami, G. Graziani, D. Tartarotti, R. Cappelli, S. Casati, A. Cantaluppi, V. Braga, V. Lo Cascio

Clin Sci (Lond) (1987) 72 (3): 329–334.

https://doi.org/10.1042/cs0720329

Published: 01 March 1987

... in five anephric subjects, six patients with chronic renal failure (CRF), two patients with vitamin D intoxication and four patients with hypoparathyroidism. 2. In anephric subjects serum 25-hydroxyvitamin D [25-(OH)D] rose from 58 ± 48 ( sd ) to 377±221 ( sd ) nmol/l after administration of 150 μg of 25...

View articletitled, Extrarenal synthesis of 1,25-dihydroxyvitamin D: Sensitivity to glucocorticoid treatment

Articles

Changing effects on erythrocyte sodium and potassium during the development of chronic renal failure with anaemia in rats

T. H. Thomas, C. Mason, K. M. Illingworth

Clin Sci (Lond) (1986) 71 (6): 639–646.

https://doi.org/10.1042/cs0710639

Published: 01 December 1986

...T. H. Thomas; C. Mason; K. M. Illingworth 1. Rats were studied 7 days and 17 days after the onset of renal failure which was induced by a surgical technique. 2. Plasma urea, creatinine ( P Cr ) and potassium had increased after 7 days; plasma potassium increased much more after 17 days but P Cr...

View articletitled, Changing effects on erythrocyte sodium and potassium during the development of chronic renal failure with anaemia in rats

Articles

Intracellular ion metabolism in erythrocytes and uraemia: The effect of different dialysis treatments

Maurizio Trevisani, Natale De Santo, Martin Laurenzi, Michele Di Muro, Franco De Chiara, Maurizio Latte, Antonietta Franzese, Roberto Iacone, Giuseppe Capodicasa, Carmelo Giordano

Clin Sci (Lond) (1986) 71 (5): 545–552.

https://doi.org/10.1042/cs0710545

Published: 01 November 1986

... countertransport dialysis erythrocytes ion transport renal failure ClinicalScience(1986) 71, 545-552 545 Intracellular ion metabolism in erythrocytes and uraemia: the effect of different dialysis treatments MAURIZIO TREVISANI, NATALE DE SANTO', MARTIN0 LAURENZI3, MICHELE DI MUROI, FRANC0 DE CHIARA...

View articletitled, Intracellular ion metabolism in erythrocytes and uraemia: The effect of different dialysis treatments

Articles

Evidence for extrarenal metabolism of 25-hydroxyvitamin D 3 in man

L. J. Fraher, S. Adami, S. E. Papapoulos, H. L. Sudan, R. J. McGonigle, V. Parsons, J. L. H. O'Riordan

Clin Sci (Lond) (1986) 71 (1): 89–95.

https://doi.org/10.1042/cs0710089

Published: 01 July 1986

... 1986 The Biochemical Society and the Medical Research Society 1986 27 1 1986 11 2 1986 calcidiol lactone 1,25-dihydroxycholecalciferol 24,25-dihydroxycholecalciferol 25,26-dihydroxycholecalciferol renal failure vitamin D metabolism-extrarenal synthesis of metabolites...

View articletitled, Evidence for extrarenal metabolism of 25-hydroxyvitamin D 3 in man

Articles

The rate of Purine Synthesis de nova in Blood Mononuclear Cells in vitro from Patients with Familial Hyperuricaemic Nephropathy

Kay D. Macdermot, Jennifer Allsop, R. W. E. Watts

Clin Sci (Lond) (1984) 67 (2): 249–258.

https://doi.org/10.1042/cs0670249

Published: 01 August 1984

... 2.4.2.7)] and ribosephosphate pyrophosphokinase (PP-ribose-P synthetase;EC 2.7.6.1)] and the concentration of phosphoribosylpyrophosphate (PP-ribose-P) in the erythrocytes of affected family members. 2. These subjects belong to families where hyperuricaemia and renal failure occur together early in life...

View articletitled, The rate of Purine Synthesis de nova in Blood Mononuclear Cells in vitro from Patients with Familial Hyperuricaemic Nephropathy

Articles

A Method for the Study of Cation Transport in vivo : Effects of Digoxin Administration and of Chronic Renal Failure on the Disposition of An Oral Load of Rubidium Chloride

N. A. Boon, J. K. Aronson, K. F. Hallis, N. J. White, A. E. G. Raine, D. G. Grahame-Smith

Clin Sci (Lond) (1984) 66 (5): 569–574.

https://doi.org/10.1042/cs0660569

Published: 01 May 1984

... in plasma rubidium concentrations and attenuated the rise in intra-erythrocytic rubidium concentrations after the oral load of rubidium chloride. 3. Ten patients with chronic renal failure, compared with a well-matched control group, were found to have changes similar to, but more marked than, those caused...

View articletitled, A Method for the Study of Cation Transport in vivo : Effects of Digoxin Administration and of Chronic Renal Failure on the Disposition of An Oral Load of Rubidium Chloride

Articles

Oxalate Dynamics and Removal Rates during Haemodialysis and Peritoneal Dialysis in Patients with Primary Hyperoxaluria and Severe Renal Failure

R. W. E. Watts, N. Veall, P. Purkiss

Clin Sci (Lond) (1984) 66 (5): 591–597.

https://doi.org/10.1042/cs0660591

Published: 01 May 1984

... clearance (RC Ox ), non-renal oxalate clearance (NRC Ox ) and the tissue oxalate accretion rate (TOA)= [(NRC Ox ) × (P Ox )] in three patients with severe renal failure due to primary hyperoxaluria who were being treated by peritoneal dialysis or haemodialysis, or by renal transplantation. The clearance...

View articletitled, Oxalate Dynamics and Removal Rates during Haemodialysis and Peritoneal Dialysis in Patients with Primary Hyperoxaluria and Severe Renal Failure

Articles

The Importance of Urinary Immunoglobulin Light Chain Isoelectric Point (Pi) in Nephrotoxicity in Multiple Myeloma

R. A. Coward, I. W. Delamore, N. P. Mallick, E. L. Robinson

Clin Sci (Lond) (1984) 66 (2): 229–232.

https://doi.org/10.1042/cs0660229

Published: 01 February 1984

... 1984 The Biochemical Society and the Medical Research Society 1984 immunoglobulin isoelectric focussing light chain nephrotoxicity multiple myeloma renal failure Clinical Science (1984) 66, 229-232 229 SHOR T COMMUNICA TION The importance of urinary immunoglobulin light chain isoelectric...

View articletitled, The Importance of Urinary Immunoglobulin Light Chain Isoelectric Point (Pi) in Nephrotoxicity in Multiple Myeloma

Articles

A Study on the Distribution of Body Fluids after Rapid Saline Expansion in Normal Subjects and in Patients with Renal Insufficiency: Preferential Intravascular Deposition in Renal Failure

Hendrik A. Koomans, Anton B. Geers, Peter Boer, Jan C. Roos, Evert J. Dorhout Mees

Clin Sci (Lond) (1983) 64 (2): 153–160.

https://doi.org/10.1042/cs0640153

Published: 01 February 1983

... renal failure the control of fluid distribution is changed in a way which leads to a preferential distribution of rapidly infused saline into the intravascular compartment. 23 4 1982 13 9 1982 © 1983 The Biochemical Society and the Medical Research Society 1983 extracellular fluid...

View articletitled, A Study on the Distribution of Body Fluids after Rapid Saline Expansion in Normal Subjects and in Patients with Renal Insufficiency: Preferential Intravascular Deposition in Renal Failure

Articles

Homocysteine in the Plasma of Renal Transplant Recipients: Effects of Cofactors for Methionine Metabolism

D. E. L. Wilcken, Vatsala J. Gupta, A. K. Betts

Clin Sci (Lond) (1981) 61 (6): 743–749.

https://doi.org/10.1042/cs0610743

Published: 01 December 1981

... cystine folic acid homocysteine homocystinuria pyridoxine renal failure vascular disease © 1981 The Biochemical Society and the Medical Research Society 1981 16 3 1981 11 6 1981 Clinical Science (1981) 61,743-749 743 Homocysteine in the plasma of renal transplant recipients...

View articletitled, Homocysteine in the Plasma of Renal Transplant Recipients: Effects of Cofactors for Methionine Metabolism

Articles

Effect of Renal Failure on Erythrocyte Purine Nucleotide, Nucleoside and Base Concentrations and Some Related Enzyme Activities

M. A. Mansell, J. Allsop, M. E. North, R. J. Simmonds, R. A. Harkness, R. W. E. Watts

Clin Sci (Lond) (1981) 61 (6): 757–764.

https://doi.org/10.1042/cs0610757

Published: 01 December 1981

...M. A. Mansell; J. Allsop; M. E. North; R. J. Simmonds; R. A. Harkness; R. W. E. Watts 1. We have studied purine metabolism in renal failure using high-pressure liquid chromatography to determine metabolite concentrations in erythrocytes and plasma, and microradiochemical assays of enzyme activity...

View articletitled, Effect of Renal Failure on Erythrocyte Purine Nucleotide, Nucleoside and Base Concentrations and Some Related Enzyme Activities

Articles

Accumulation of Sulphur-Containing Amino Acids Including Cysteine-Homocysteine in Patients on Maintenance Haemodialysis

D. E. L. Wilcken, Vatsala J. Gupta, S. G. Reddy

Clin Sci (Lond) (1980) 58 (5): 427–430.

https://doi.org/10.1042/cs0580427

Published: 01 May 1980

...D. E. L. Wilcken; Vatsala J. Gupta; S. G. Reddy 1. Plasma sulphur-containing amino acids were measured in 19 patients with renal failure on chronic haemodialysis and in 22 normal subjects, to determine the rate of accumulation of these amino acids in chronic azotaemia. 2. Cysteine-homocysteine...

View articletitled, Accumulation of Sulphur-Containing Amino Acids Including Cysteine-Homocysteine in Patients on Maintenance Haemodialysis

Articles

Effects of Indomethacin on the Metabolism of Glycerol by Rat-Kidney Tubules: An Alternative Explanation for the Enhancement of Glycerol-Induced Acute Renal Failure by Indomethacin

Elizabeth Craig, G. J. Cooney, A. G. Dawson

Clin Sci (Lond) (1980) 58 (4): 337–340.

https://doi.org/10.1042/cs0580337

Published: 01 April 1980

... production rose significantly when indomethacin was present, indicating a fall in the rate at which glycerol 3-phosphate was oxidized. 4. The results are discussed in relation to the observation that indomethacin increases the severity of glycerol-induced acute renal failure. © 1980 The Biochemical Society...

View articletitled, Effects of Indomethacin on the Metabolism of Glycerol by Rat-Kidney Tubules: An Alternative Explanation for the Enhancement of Glycerol-Induced Acute Renal Failure by Indomethacin

Articles

Responsiveness to Prazosin in Renal Failure

G. S. Stokes, J. C. Monaghan, G. W. Frost, E. P. MacCarthy

Clin Sci (Lond) (1979) 57 (s5): 383s–385s.

https://doi.org/10.1042/cs057383s

Published: 01 December 1979

...G. S. Stokes; J. C. Monaghan; G. W. Frost; E. P. MacCarthy 1. The fall in blood pressure produced by a test dose of prazosin was greater in a group of patients with chronic renal failure than in a group with normal renal function. 2. This difference could not be attributed to increased reactivity...

View articletitled, Responsiveness to Prazosin in Renal Failure

Articles

Distribution of Circulating Immunoreactive Components of Parathyroid Hormone in Normal Subjects and in Patients with Primary and Secondary Hyperparathyroidism: The Role of the Kidney and of the Serum Calcium Concentration

M. A. Dambacher, J. A. Fischer, W. H. Hunziker, W. Born, J. Moran, H.-R. Roth, E. E. Delvin, F. H. Glorieux

Clin Sci (Lond) (1979) 57 (5): 435–443.

https://doi.org/10.1042/cs0570435

Published: 01 November 1979

... renal failure as compared with those of normal subjects. Mean amounts of peak II were higher in patients with chronic renal insufficiency than in nutritional vitamin D deficiency, in pseudohypoparathyroidism and in primary hyperparathyroidism, despite comparable amounts of PTH-(1–84). 3. In chronic...

View articletitled, Distribution of Circulating Immunoreactive Components of Parathyroid Hormone in Normal Subjects and in Patients with Primary and Secondary Hyperparathyroidism: The Role of the Kidney and of the Serum Calcium Concentration

Articles

Study of the Oligosaccharide Units from Mucus Glycoproteins of Meconium from Normal Infants and from Cases of Cystic Fibrosis with Meconium Ileus

J. R. Clamp, M. Gough

Clin Sci (Lond) (1979) 57 (5): 445–451.

https://doi.org/10.1042/cs0570445

Published: 01 November 1979

... specimens. 9 1 1979 17 7 1979 © 1979 The Biochemical Society and the Medical Research Society 1979 renal failure cystic fibrosis glycoproteins meconium, mucus Clinical Science (1979) 57,445-45 1 Study of the oligosaccharide units from mucus glycoproteins of meconium from normal...

View articletitled, Study of the Oligosaccharide Units from Mucus Glycoproteins of Meconium from Normal Infants and from Cases of Cystic Fibrosis with Meconium Ileus

Articles

Plasma 25-Hydroxy-Vitamin D in Normal Subjects and Patients with Terminal Renal Failure, on Maintenance Haemodialysis and after Transplantation

J. B. Eastwood, A. Daly, G. D. Carter, J. Alaghband-Zadeh, H. E. De Wardener

Clin Sci (Lond) (1979) 57 (5): 473–476.

https://doi.org/10.1042/cs0570473

Published: 01 November 1979

...J. B. Eastwood; A. Daly; G. D. Carter; J. Alaghband-Zadeh; H. E. De Wardener 1. Plasma 25-hydroxy-vitamin D concentration was measured in 40 normal subjects, 19 patients with terminal renal failure, 137 patients who had been on dialysis up to 11 years and in 17 renal transplant patients. 2...

View articletitled, Plasma 25-Hydroxy-Vitamin D in Normal Subjects and Patients with Terminal Renal Failure, on Maintenance Haemodialysis and after Transplantation

Articles

Role of Endotoxin in Glycerol-Induced Renal Failure in the Rat

J. P. Nolan, R. C. Venuto, Gwendolyn S. Goldmann

Clin Sci Mol Med (1978) 54 (6): 615–620.

https://doi.org/10.1042/cs0540615

Published: 01 June 1978

...J. P. Nolan; R. C. Venuto; Gwendolyn S. Goldmann 1. A relationship between bacterial endotoxin absorbed from the gut and acute renal failure has been postulated. Experiments employing either the endotoxin-tolerant state or the enhancement of endotoxin injury were undertaken to test...

View articletitled, Role of Endotoxin in Glycerol-Induced Renal Failure in the Rat

Articles

Hepatic Metabolism of Aminopyrine in Patients with Chronic Renal Failure

S. Scherrer, B. Haldimann, A. Küpfer, F. Reubi, J. Bircher

Clin Sci Mol Med (1978) 54 (2): 133–140.

https://doi.org/10.1042/cs0540133

Published: 01 February 1978

...S. Scherrer; B. Haldimann; A. Küpfer; F. Reubi; J. Bircher 1. To evaluate potential alterations in hepatic metabolism of drugs occurring in patients with renal insufficiency the fate of aminopyrine was studied in 17 patients with chronic renal failure and in 27 normal subjects. 2. Although patients...

View articletitled, Hepatic Metabolism of Aminopyrine in Patients with Chronic Renal Failure

Articles

Arrested Bone Growth and Mineral Maturation in Sub-Totally Nephrectomized Rats

J. M. Letteri, R. M. Biltz, K. J. Ellis, A. Martino, S. Yasumura, D. Brook, S. H. Cohn, E. D. Pellegrino

Clin Sci Mol Med (1977) 53 (5): 479–484.

https://doi.org/10.1042/cs0530479

Published: 01 November 1977

...J. M. Letteri; R. M. Biltz; K. J. Ellis; A. Martino; S. Yasumura; D. Brook; S. H. Cohn; E. D. Pellegrino 1. Young, sub-totally nephrectomized rats were used to study the altered mineral metabolism of renal failure and its effects on bone growth and mineral maturation. 2. Rats killed at 4 weeks...

View articletitled, Arrested Bone Growth and Mineral Maturation in Sub-Totally Nephrectomized Rats

Articles

Plasma Calcitonin in Chronic Renal Failure: Relation to other Factors of Importance in Bivalent Ion Metabolism

R. Shainkin-Kestenbaum, R. Lerman, A. Reuben, G. M. Berlyne

Clin Sci Mol Med (1977) 52 (6): 577–583.

https://doi.org/10.1042/cs0520577

Published: 01 June 1977

...R. Shainkin-Kestenbaum; R. Lerman; A. Reuben; G. M. Berlyne 1. Plasma concentrations of human calcitonin were measured in groups of patients with chronic renal failure, treated either conservatively or by haemodialysis, and compared with a normal group of persons. 2. Plasma calcitonin...

View articletitled, Plasma Calcitonin in Chronic Renal Failure: Relation to other Factors of Importance in Bivalent Ion Metabolism

Articles

The Effect of 25-Hydroxy Vitamin D 3 in the Osteomalacia of Chronic Renal Failure

J. B. Eastwood, T. C. B. Stamp, H. E. De Wardener, P. J. Bordier, C. D. Arnaud

Clin Sci Mol Med (1977) 52 (5): 499–508.

https://doi.org/10.1042/cs0520499

Published: 01 May 1977

...J. B. Eastwood; T. C. B. Stamp; H. E. De Wardener; P. J. Bordier; C. D. Arnaud 1. Five patients with the osteomalacia of chronic renal failure were given 50–100 nmol of 25-hydroxy vitamin D 3 intravenously per day for 24–28 days. 2. In all five patients, during administration of 25-hydroxy vitamin...

View articletitled, The Effect of 25-Hydroxy Vitamin D 3 in the Osteomalacia of Chronic Renal Failure

Articles

Selective Hypoaldosteronism: A Study of Steroid Biosynthetic Pathways under Adrenocorticotrophin and Angiotensin II Infusion

M. Lebel, J. H. Grose

Clin Sci Mol Med (1976) 51 (s3): 335s–337s.

https://doi.org/10.1042/cs051335s

Published: 01 December 1976

... adrenocorticotrophin aldosterone angiotensin II hyperkalaemia renin renal failure Clinical Science and Molecular Medicine (1976) 51. 335s-337s. Selective hypoaldosteronism: a study of steroid biosynthetic pathways under adrenocorticotrophin and angiotensin 11 infusion M. LEBEL A N D J. H . GROSE Nephrology...

View articletitled, Selective Hypoaldosteronism: A Study of Steroid Biosynthetic Pathways under Adrenocorticotrophin and Angiotensin II Infusion

Articles

Significance of Increase in Labelled Albumin Disappearance Rate in Arterial Hypertension

M. Ulrych, Z. Ulrych

Clin Sci Mol Med (1976) 51 (s3): 211s–213s.

https://doi.org/10.1042/cs051211s

Published: 01 December 1976

... 1976 albumin blood pressure blood volume capillary Evans Blue heart failure liver cirrhosis packed cell volume renal artery stenosis renal failure renin Clinical Science and Molecular Medicine (1976) 51, 211s-213s. Significance of increase in labelled albumin disappearance rate...

View articletitled, Significance of Increase in Labelled Albumin Disappearance Rate in Arterial Hypertension

Articles

The Effect of Aluminium Hydroxide Orally on Calcium, Phosphorus and Aluminium Metabolism in Normal Subjects

J. M. Cam, V. A. Luck, J. B. Eastwood, H. E. de Wardener

Clin Sci Mol Med (1976) 51 (4): 407–414.

https://doi.org/10.1042/cs0510407

Published: 01 October 1976

.... This was accompanied by a rise in the concentration of the fasting morning plasma phosphorus. Calcium balance did not change. 3. The normal subjects absorbed 0·3–3·6 mmol of aluminium/day, which is significantly less than that absorbed by five patients with chronic renal failure, three of whom were studied before...

View articletitled, The Effect of Aluminium Hydroxide Orally on Calcium, Phosphorus and Aluminium Metabolism in Normal Subjects

Articles

Increased Plasma Calcitonin in Early Acute Renal Failure

R. Ardaillou, M. Beaufils, Marie-Paule Nivez, R. Isaac, C. Mayaud, J.-D. Sraer

Clin Sci Mol Med (1975) 49 (4): 301–304.

https://doi.org/10.1042/cs0490301

Published: 01 October 1975

...R. Ardaillou; M. Beaufils; Marie-Paule Nivez; R. Isaac; C. Mayaud; J.-D. Sraer 1. High plasma immunoreactive calcitonin concentrations were observed in ten of eleven patients with acute renal failure, particularly in the oliguric phase. 2. Immunoreactive calcitonin decreased progressively with time...

View articletitled, Increased Plasma Calcitonin in Early Acute Renal Failure

Articles

Platelet Survival in Acute Proliferative Glomerulonephritis

J. A. Carruthers, I. Ralfs, T. M. D. Gimlette, R. Finn

Clin Sci Mol Med (1974) 47 (5): 507–513.

https://doi.org/10.1042/cs0470507

Published: 01 November 1974

...J. A. Carruthers; I. Ralfs; T. M. D. Gimlette; R. Finn 1. Platelet survival was measured in patients with acute proliferative glomerulonephritis or chronic renal failure and also in control subjects. 2. Platelet survival is markedly reduced in acute proliferative glomerulonephritis as compared...

View articletitled, Platelet Survival in Acute Proliferative Glomerulonephritis

Articles

Lung Function in Chronic Uraemia before and after Removal of Excess of Fluid by Haemodialysis

D. C. Stănescu, C. Veriter, J. F. De Plaen, A. Frans, C. Van Ypersele De Strihou, L. Brasseur

Clin Sci Mol Med (1974) 47 (2): 143–151.

https://doi.org/10.1042/cs0470143

Published: 01 August 1974

... lung volume. 2 11 1973 © 1974 The Biochemical Society and the Medical Research Society 1974 renal failure pulmonary oedema closing volume lung function Clinical Science and Molecular Medicine (1974) 47, 143-151. L U N G F U N C T I O N I N CHRONIC U R A E M I A BEFORE A N D...

View articletitled, Lung Function in Chronic Uraemia before and after Removal of Excess of Fluid by Haemodialysis

Articles

The Contrasting Effects on Bone Histology of Vitamin D and of Calcium Carbonate in the Osteomalacia of Chronic Renal Failure

J. B. Eastwood, P. J. Bordier, E. M. Clarkson, S. Tun Chot, H. E. De Wardener

Clin Sci Mol Med (1974) 47 (1): 23–42.

https://doi.org/10.1042/cs0470023

Published: 01 July 1974

...J. B. Eastwood; P. J. Bordier; E. M. Clarkson; S. Tun Chot; H. E. De Wardener 1. The histological appearances of cancellous bone from the ilium have been quantified in thirteen patients with osteomalacia due to chronic renal failure. 2. There was an excess of osteoid tissue and a reduction...

View articletitled, The Contrasting Effects on Bone Histology of Vitamin D and of Calcium Carbonate in the Osteomalacia of Chronic Renal Failure

Articles

Interrelationships between Blood Pressure, Renin, Renin Substrate and Blood Volume in Terminal Renal Failure

M. A. D. H. Schalekamp, M. P. A. Schalekamp-Kuyken, M. de Moor-Fruytier, Th. Meininger, D. J. Vaandrager-Kranenburg, W. H. Birkenhäger

Clin Sci Mol Med (1973) 45 (4): 417–428.

https://doi.org/10.1042/cs0450417

Published: 01 October 1973

... 1973 hypertension renal failure renin renin substrate blood volume Clinical Science and Molecular Medicine (1973) 45,417428. INTERRELATIONSHIPS BETWEEN BLOOD PRESSURE, RENIN, RENIN SUBSTRATE A N D BLOOD VOLUME I N TERMINAL RENAL FAILURE M . A. D. H . SCHALEKAMP, M. P. A. SCHALEKAMP-KUYKEN...

View articletitled, Interrelationships between Blood Pressure, Renin, Renin Substrate and Blood Volume in Terminal Renal Failure

Articles

Haemodynamic and Blood Volume Studies in Long-Term Haemodialysis Patients, and in Patients with Successfully Transplanted Kidneys

J. Tuckman, J.-L. Benninger, F. Reubi

Clin Sci Mol Med (1973) 45 (s1): 155s–157s.

https://doi.org/10.1042/cs045155s

Published: 01 August 1973

... haemodialysis hypertension renal failure renal transplantation cardiac index blood volume Clinical Science and Molecular Medicine (1973) 45, 155s-157s. HAEMODYNAMIC A N D BLOOD VOLUME STUDIES I N LONG-TERM HAEMODIALYSIS PATIENTS, A N D I N PATIENTS WITH SUCCESSFULLY TRANSPLANTED KIDNEYS J. TUCKMAN. J.-L...

View articletitled, Haemodynamic and Blood Volume Studies in Long-Term Haemodialysis Patients, and in Patients with Successfully Transplanted Kidneys

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