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Keywords: renal hypertension
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Articles
Clin Sci (Lond) (1984) 66 (3): 351–355.
Published: 01 March 1984
... + content ratio suggest an inhibition of the Na + pump in the patients with chronic renal disease. 4. The inhibition of the Na + pump may be secondary to the hypervolaemia which we suggest is the initial event leading to renal hypertension. 6 11 1983 24 10 1983 © 1984 The Biochemical...
Articles
Clin Sci (Lond) (1983) 64 (3): 355–358.
Published: 01 March 1983
...Ricardo Exequiel Chatelain 1. To determine the possible role of arterial cyclic AMP in the pathogenesis of hypertensive vascular hypertrophy and hyperplasia, the changes in the level of this nucleotide were studied during the development of renal hypertension in rats with aortic ligation between...
Articles
Clin Sci (Lond) (1982) 63 (s8): 211s–213s.
Published: 01 October 1982
...Yutaka Takata; Austin E. Doyle; Margherita Veroni; Stuart G. Duffy 1. The aim of this study was to determine whether the urinary excretory function of the contralateral kidney is essential for angiotensin dependency in two-kidney, one-clip renal hypertensive rats. Ureteric ligation was used...
Articles
Clin Sci (Lond) (1981) 60 (6): 625–631.
Published: 01 June 1981
.... 7. PGE released from the kidney may be important in mediating the excretion of sodium and water that is retained during the development of renal hypertension. 16 1 1981 2 2 1981 © 1981 The Biochemical Society and the Medical Research Society 1981 aldosterone dialysis...
Articles
Clin Sci (Lond) (1981) 60 (4): 387–392.
Published: 01 April 1981
... plasma renin activity is undetectable. 6 5 1980 22 10 1980 © 1981 The Biochemical Society and the Medical Research Society 1981 angiotensin I-converting enzyme bradykinin captopril renal hypertension Clinical Science (1981) 60. 387-392 387 Effect of the converting-enzyme...
Articles
Clin Sci (Lond) (1980) 59 (s6): 183s–185s.
Published: 01 December 1980
... with renal hypertension (0.475 ± 0.250 μmol of phosphate h −1 mg −1 ) ( P <0.025). 4. There was no difference in ouabain-insensitive ATPase between the controls and the different types of hypertension. 5. The data support the hypothesis of an activation of the Na + pump in patients with glucocorticoid...
Articles
Clin Sci (Lond) (1980) 59 (s6): 335s–338s.
Published: 01 December 1980
...G. L. Rorive; P. J. Carlier; J. M. Foidart 1. Renal hypertension produces a marked and rapidly detectable hypertrophy of the rat aorta, due to smooth muscle cell hyperplasia and connective tissue deposition. 2. As we described previously for collagen synthesis, cell hyperplasia is a very early...
Articles
Clin Sci (Lond) (1980) 59 (s6): 153s–156s.
Published: 01 December 1980
... renal hypertension Clinical Science (1980) 59,153s-156s 153s Blood volume and interstitial fluid pressure in the development and reversal of renal hypertension in rats N . C. T R I P P O D O A N D L . P . Z I E G L E R Division of Research, AIton Ochsner Medical Foundation, New Orleans, Louisiana, U...
Articles
Clin Sci (Lond) (1979) 57 (s5): 337s–339s.
Published: 01 December 1979
... in normotensive control (NC) rats, spontaneously hypertensive (SH) rats, rats with short-standing renal hypertension induced early in pregnancy and rats with established renal hypertension induced 4 weeks before pregnancy. Non-pregnant rats in comparable states served as controls. 2. In normal pregnancy cardiac...
Articles
Clin Sci (Lond) (1979) 57 (s5): 15s–17s.
Published: 01 December 1979
...Margareta Hallbäck-Nordlander; E. Noresson; Y. Lundgren 1. Cardiac output, heart rate and mean arterial pressure were determined in two-kidney Goldblatt hypertensive rats of 4 weeks' duration, in matched normotensive controls and in declipped renal hypertensive rats 2 h-28 days after renal artery...
Articles
Clin Sci (Lond) (1979) 56 (3): 227–233.
Published: 01 March 1979
... plasma kininogen plasma urea plasma volume renal tissue kininogenase activity renal hypertension urinary kallikrein Clinical Science (1979) 56,227-233 Kallikrein-kinin system in one- and two-kidney Goldblatt hypertensive rats R. ALBERTINI , R. ROSAS, H. R. CROXATTO A N D J . ROBLERO Instituto de...
Articles
Clin Sci Mol Med (1978) 55 (s4): 167s–169s.
Published: 01 December 1978
... of magnitude as that of pepstatin A. 4. In renal hypertensive rats, the bolus injection of pepstatinyl-arginine- O -methyl-ester or of the arginine salt of pepstatin decreased blood pressure to the same extent as a bolus injection of Sar 1 , Ala 8 -angiotensin II. Clinical Science and Molecular Medicine (1978...
Articles
Clin Sci Mol Med (1978) 55 (s4): 45s–56s.
Published: 01 December 1978
... role in the development of the high blood pressure. (c) Renal hypertension: both central and peripheral nervous mechanisms contribute to the development and the early phase of ‘one-kidney’ hypertension in animals. Their role in the maintenance of this form of hypertension is still controversial. (d...
Articles
Clin Sci Mol Med (1978) 55 (s4): 211s.
Published: 01 December 1978
...Dr D. Ganten © 1978 The Biochemical Society and the Medical Research Society 1978 Nomenclature Committee Report renal hypertension Clinical Science and Molecular Medicine (1978) 55.2 1 1s I Nomenclature of experimental renal hypertension Goldblatt Page Grollman Two kidney. Two kidney...
Articles
Clin Sci Mol Med (1978) 55 (s4): 217s–220s.
Published: 01 December 1978
... of the peptide can sustain a higher arterial pressure than it can during acute infusions. © 1978 The Biochemical Society and the Medical Research Society 1978 angiotensin II blood pressure sodium aldosterone renal hypertension Clinical Science and Molecular Medicine ( 1978) 55.2 17s-220s...
Articles
Clin Sci Mol Med (1978) 55 (2): 149–156.
Published: 01 August 1978
...R. E. Chatelain; C. M. Ferrario 1. Structural changes in the thymus during the evolution of experimental renal hypertension were investigated to determine their possible role in the genesis of hypertensive vascular disease. 2. The thymus, adrenal glands and the progression of hypertensive vascular...
Articles
Clin Sci Mol Med (1978) 55 (1): 81–87.
Published: 01 July 1978
... extracellular space plasma volume renal hypertension salt-free diet 10 10 1977 13 2 1978 Clinical Science and Molecular Medicine (1978) 5 5 , 8 1 4 7 Determinants of high blood pressure in salt-deprived renal hypertensive rats: role of changes in plasma volume, extracellular fluid volume...
Articles
Clin Sci Mol Med (1978) 54 (5): 561–566.
Published: 01 May 1978
... hypertension renal prostaglandin Renal prostagiandins in renal hypertensive dogs K. K. DIGHE, G. W. SMITH, A. UNGAR AND P. H. WHELPDALE Department of Pharmacology, University of Edinburgh, Edinburgh, Scotland, U.K. (Received 28 June 1977; accepted 13 December 1977) Clinical Science and Molecular Medicine...
Articles
Clin Sci Mol Med (1977) 52 (2): 163–170.
Published: 01 February 1977
... arterial pressure to fall during the acute but not the chronic phase of renal hypertension. In this latter phase plasma renin activity had returned to control values. 4. We conclude that the renin—angiotensin system appears not to be directly involved in the chronic phase of two-kidney hypertension...
Articles
Clin Sci Mol Med (1976) 51 (s3): 361s–364s.
Published: 01 December 1976
... circumflex conductance appear to be absent in renal hypertension. 5. The absence of the transient autonomic rise in circumflex flow and conductance in response to rapid elevations in aortic pressure in certain forms of hypertension, e.g. during tachyarrhythmias and behavioural disturbances, may result...
Articles
Clin Sci Mol Med (1976) 51 (s3): 227s–230s.
Published: 01 December 1976
... Research Society 1976 extracellular volume renal hypertension renin—angiotensin system transplantation Clinical Science and Molecular Medicine (1976) 51,227s-230s. Plasma renin activity, plasma angiotensin I1 and extracellular fluid volume in patients after renal transplantation J . S. HORVATH...
Articles
Clin Sci Mol Med (1976) 51 (s3): 231s–233s.
Published: 01 December 1976
...R. M. Graham; E. F. Sebel; G. S. Stokes 1. A prospective study was undertaken in seventy-eight patients with renal hypertension (fifty-eight with renovascular disease and twenty with renal parenchymal disease), after their presentation to an advisory group as possible candidates for surgical...
Articles
Clin Sci Mol Med (1976) 51 (s3): 243s–245s.
Published: 01 December 1976
...F. Skrabal; W. Czaykowska; P. Dittrich; H. Braunsteiner 1. The immediate short-term effects of intravenous injections of propranolol on plasma renin activity were studied in thirty-one normal subjects, 102 patients with benign essential and sixty-six patients with renal hypertension. 2...
Articles
Clin Sci Mol Med (1976) 51 (s3): 57s–59s.
Published: 01 December 1976
... nervous system renal hypertension smooth muscle tone vascular reactivity vascular resistance Clinical Science and Molecular Medicine (1976) 51, 57s-59s. Assessment of autonomic and non-autonomic components of resting hindlimb vascular resistance and reactivity to pressor substances in renal...
Articles
Clin Sci Mol Med (1976) 51 (s3): 129s–132s.
Published: 01 December 1976
...M. Fernandes; G. Onesti; R. Dykyj; R. Fiorentini; Anne B. Gould; K. E. Kim; C. Swartz 1. Sodium-deficient diet failed to alter development and maintenance of severe renal hypertension produced in the rat by ligation of the aorta between the renal arteries. 2. High sodium diet did not alter...
Articles
Clin Sci Mol Med (1976) 51 (s3): 137s–139s.
Published: 01 December 1976
... of 10%. The rise in cardiac output was more transient than in other species, and was not essential for subsequent development of hypertension. © 1976 The Biochemical Society and the Medical Research Society 1976 cardiac output renal hypertension vascular resistance Clinical Science...
Articles
Clin Sci Mol Med (1976) 51 (s3): 69s–71s.
Published: 01 December 1976
.... © 1976 The Biochemical Society and the Medical Research Society 1976 malignant hypertension renal hypertension renin Clinical Science and Molecular Medicine (1976) 51,69~-71s. Accelerated hypertension in the rat: relation between renin, renal vascular lesions, salt intake and blood...
Articles
Clin Sci Mol Med (1975) 48 (2): 147–151.
Published: 01 February 1975
...C. S. Sweet; M. Mandradjieff 1. Renal hypertensive dogs were treated with hydrochlorothiazide (8−2 μmol/kg or 33 μmol/kg daily for 7 days), or timolol (4.6 μmol/kg daily for 4 days), a potent β-adrenergic blocking agent, or combinations of these drugs). Changes in mean arterial blood pressure...
Articles
Clin Sci Mol Med (1975) 48 (2): 115–119.
Published: 01 February 1975
... role in renin-dependent hypertension. 1 10 1974 © 1975 The Biochemical Society and the Medical Research Society 1975 angiotensin renal hypertension area postrema Clinical Science and Molecular Medicine (1975) 48. 115-119. Evidence for a significant contribution from central...
Articles
Clin Sci Mol Med (1975) 48 (1): 17–26.
Published: 01 January 1975
...) and severe (200–230 mmHg; clip i.d. 0.20 mm) renal hypertension in rats with an undisturbed contralateral kidney. 2. In severely hypertensive rats renin activity in the peripheral plasma increased from day 9, by which time the systolic blood pressure was elevated to 160–180 mmHg. The rate of total...
Articles
Clin Sci Mol Med (1975) 48 (s2): 279s–282s.
Published: 01 January 1975
... in control animals and reversed it when given after sustained neurogenic hypertension had developed in denervated animals. These studies suggest that central serotonergic neurons participate in the baroreceptor reflex arc. 4. Intracisternal 5,6-DHT did not modify the renal hypertension that follows bilateral...
Articles
Clin Sci Mol Med (1974) 47 (1): 1–11.
Published: 01 July 1974
...J. Lucas; M. A. Floyer 1. To determine the part played by changes in interstitial tissue compliance in the mechanism of experimental renal hypertension, pressure and volume measurements were made in rats 60 days after partial constriction of one renal artery with a clip and removal of the opposite...
Articles
Clin Sci Mol Med (1973) 45 (5): 701–709.
Published: 01 November 1973
... followed by injection of clonidine (1 μg/kg) into the cisterna magna lowered mean arterial pressure (MAP) from 100·5 ± 1·5 mmHg to 45·0 ± 2·5 mmHg. In normal animals treated similarly MAP fell from 79·1 ± 2·3 mmHg to 49·1 ± 3·9 mmHg. 3. In renal hypertensive rabbits with cellophane perinephritis...
Articles
Clin Sci Mol Med (1973) 45 (s1): 115s–118s.
Published: 01 August 1973
... to intraventricular angiotensin (100 ng) was decreased in normotensive rabbits pretreated with intracisternal 6-OHD from a pressure rise of 20 mmHg in 1 min to 10 mmHg in 1 min. © 1994 The Biochemical Society and the Medical Research Society 1994 renal hypertension 6-hydroxydopamine angiotensin central...
Articles
Clin Sci Mol Med (1973) 45 (s1): 251s–255s.
Published: 01 August 1973
...G. Dauda; J. Möhring; K. G. Hofbauer; E. Homsy; Ulrike Miksche; H. Orth; F. Gross 1. In renal hypertensive rats, increase in blood pressure above 180 mmHg may induce sodium and water loss, reduced growth rate, elevated haematocrit, a marked rise in plasma renin concentration, an increase in renin...
Articles
Clin Sci (1972) 43 (4): 577–581.
Published: 01 October 1972
... ratio, sodium balance, aldosterone, renal hypertension. The development of secondary aldosteronism in experimental hypertension appears to be critically dependent upon the procedure used. In the sheep and rat there is evidence that hypertension produced by unilateral renal ischaemia is associated...