... in the renal kallikrein content in this hypertensive model. 2. Active and total kallikrein were measured (amidolytic assay) in the renal cortex of newborn and 4-, 8- and 12-week-old SHR and age-matched WKY. Active and total kallikrein were also measured in urine at the same ages, except at birth. 3. Tissue...

...M. Marin-Grez; G. Schaechtelin; G. Bönner; G. Speck; D. Ganten; F. Gross 1. Rats were made hypertensive by ligating the aorta between the origins of both renal arteries. Sham-operated animals served as controls. Urinary and renal kallikrein activities, as well as plasma and renal renin activities...

..., and that this release can be hormonally regulated by a mechanism involving prostaglandin synthesis. arachidonic acid indomethacin isolated kidney kallikrein-kinin system renal prostaglandins renal kallikrein © 1982 The Biochemical Society and the Medical Research Society 1982 Clfnical Science (1982...

... i.u. of renin strikingly reduced kallikrein excretion ( P < 0·01) but considerably increased sodium excretion ( P < 0·001). 2. Renal kallikrein, measured by its kininogenase activity within 2 h of water loading, was significantly increased ( P < 0·05); after water loading and frusemide...