...R. Vandongen; Dianne M. Greenwood 1. The effect of adrenaline and noradrenaline on renin secretion in the isolated perfused rat kidney was examined. The doses of catecholamines used were such that renal vasoconstriction and therefore increases in renal perfusion pressure were avoided. Under...

..., did not prevent the increase seen with renal artery constriction. 4. Reduction of renal perfusion pressure within the autoregulatory range for 20 min resulted in a rise in PRA in all experiments. (±)-Propranolol did not significantly affect the response. 5. It is concluded that the release of renin...