... for non-clipped kidneys increased from 5.9 ± 0.4 to 6.5 ± 0.3 ml/min, indicating a 30% reduction of renal vascular resistance ( P values 0.01; n = 9). Glomerular filtration rate (GFR) for non-clipped kidneys ( n = 24) increased from 0.91 ± 0.09 to 1.47 ± 0.14 ml/min and filtration fraction increased from...

... pressure. The increases in renal blood flow and GFR were less than those observed in the non-clipped kidneys of hypertensive rats. 5. These data provide further support to the hypothesis that an angiotensin II-mediated elevation in renal vascular resistance and impairment of renal function exist in the non...

... blood pressure. 2. At their respective spontaneous blood pressures, renal vascular resistance was higher and glomerular filtration rate (GFR) and renal blood flow were not different in the contralateral kidneys of the hypertensive rats (170 ± 5 mmHg) compared with normal animals (129 ± 1 mmHg). Urine...

... rats, blood pressure did not rise in rats with diabetes insipidus after the injection of glycerol. 5. When 2 h after the injection of glycerol kidneys were taken from rats with diabetes insipidus and perfused with an electrolyte solution in a single-pass system for 1 h, renal vascular resistance was 30...

... (Haemaccel, 35 g/l) at pressures between 90 and 100 mmHg in a single-pass system. 2. In kidneys taken from rats with acute renal failure renal vascular resistance was markedly increased immediately after the start of the perfusion as compared with control kidneys taken from untreated rats. During...

... was found to decrease temporarily in some subjects. The ultimate change was a gradual rise. In those subjects who suffered myocardial infarction renin tended to rise more sharply. 3. A relationship was established with the rise in renal vascular resistance, which almost invariably occurred over the years...