...Kaj Metsärinne; Frej Fyhrquist; Carola Grönhagen-Riska 1. Renin substrate (RS) and certain serine protease inhibitors share structural homology. Previous studies have shown that RS may be an acute-phase protein. 2. This prospective study was carried out to monitor plasma RS and other components...

...S. Rasmussen; M. Damkjaer Nielsen; J. Giese 1. We have measured plasma concentrations of renin, renin substrate and angiotensins I and II as well as plasma renin activity in nine patients with severe or malignant hypertension during treatment with captopril, hydrochlorothiazide and propranolol. 2...

...P. F. Semple; W. A. MacRae; J. J. Morton 1. Concentrations of angiotensin II (ANG II) were measured by radioimmunoassay in cerebrospinal fluid and plasma from neurosurgical patients and patients having spinal anaesthesia. Cerebrospinal fluid concentrations of renin, renin substrate and ANG I were...

...Eiki Murakami; Kunio Hiwada; Tatsuo Kokubu 1. The effects of prostaglandin (PG) E 1 , PGE 2 and PGF 2α on plasma renin substrate concentration in rats and renin substrate production by perfused rat liver were investigated. 2. After bilateral nephrectomy, both plasma renin substrate concentration...

...J. Menard; F.-X. Galen; C. Devaux; N. Kopp; Colette Auzan; P. Corvol 1. Human plasma, amniotic fluid and acidified amniotic fluid were incubated at pH 5.5 with the same concentrations of human plasma renin substrate and rat plasma renin substrate. They produced three to eight times more angiotensin...

... renin renin substrate Clinical Science (1979) 57,101~103s Release of active and inactive renin by the human kidney W. AOI, S. SETO, Y. DOI, M. MURAYAMA, S. TASAKI , S. SUZUKI , M. K U R A M O C H I AND K. HASHIBA Third Departmenr of Internal Medicine, Nagasaki University School of Medicfne, Nagasaki...

... pairs). 4. Both factors contribute towards the prolongation of the blood pressure increase after intravenously administered renin in the nephrectomized animal. © 1976 The Biochemical Society and the Medical Research Society 1976 angiotensin I immunoassay renin clearance renin substrate...

... urine flow and the sum of fractional free water and sodium clearances) increased significantly in both groups. The progesterone-induced increase in sodium excretion was not related to changes in plasma renin activity, renin substrate or urinary aldosterone. After 3 days of progesterone, the increase...

... concentration (PRC), plasma renin substrate (PRS) and blood volume. Parallel measurements of PRC and blood volume were carried out before and during the period of regular dialysis treatment. PRS was measured during this period only. 2. Both before and during regular dialysis PRC was higher in relation to blood...

...E. Rosset; J. R. Scherrer; R. Veyrat 1. In normal man, in deoxycorticosterone/salt hypertension, and in renal artery stenosis, an inverse relationship between plasma renin activity (PRA) and renin-substrate (RS) is found. 2. PRA and RS were found to be inversely related in primary aldosteronism...

...L. R. Krakoff; M. Mendlowitz 1. Plasma renin activity and plasma renin substrate were measured by radioimmunoassay of generated angiotensin I in patients with steroid excess syndromes. Significant increases in substrate were observed in patients with Cushing's syndrome, during glucocorticoid...

...K. G. Hofbauer; H. Zschiedrich; W. Rauh; F. Gross 1. In the isolated rat kidney, perfused at constant pressure with a medium free from renin substrate, addition of angiotensin I to the perfusate decreases renal ‘plasma’ flow. 2. A peptide inhibitor, SQ 20881, of converting enzyme reduces...

...S. L. Skinner; Eugenie R. Lumbers; E. M. Symonds 1. Determinations of plasma renin activity (PRA), plasma renin concentration (PRC) and renin substrate (RS) were made on single plasma samples from thirty-four women at various stages of pregnancy. Comparisons were made with non-pregnant control...