... another. 5. These results show that arginine in high dose is a vasodilator in both human resistance vessels and superficial veins in vivo. The response to arginine was not stereospecific: both the l - and d -enantiomers had the same effect. The dilator effect of high-dose arginine showed neither arterio...

...C. Aalkjaer; H. Danielsen; P. Johannesen; E. B. Pedersen; A. Rasmussen; M. J. Mulvany 1. In order to obtain direct information about vascular changes associated with pre-eclampsia, the morphological and functional characteristics of isolated omental resistance vessels from 11 women with pre...

... no long-lasting effect on 150 μm mesenteric and 150 μm femoral resistance vessels over a 3 h period. Much lower concentrations of ouabain (1 μmol/l) caused contraction of guinea pig aorta, but had no effect on the mesenteric and femoral resistance vessels. 3. In the mesenteric resistance vessels, ouabain...

...-activated calcium sensitivity of spontaneously hypertensive rat blood vessels may be associated with an increased sodium-potassium-ATPase activity. © 1980 The Biochemical Society and the Medical Research Society 1980 calcium sodium-potassium-dependent ATPase resistance vessels spontaneous...

...M. J. Mulvany; C. Aalkjær; J. Christensen 1. We have compared the noradrenaline sensitivity of 150 μm arterial resistance vessels taken from a specific place in the mesenteric bed of spontaneously hypertensive (SH) rats and of control Wistar—Kyoto (WK) rats at three ages: 6 weeks, 12 weeks and 24...

... control rats. 3. All parameters reflecting design and reactivity of the resistance vessels and left ventricular weight decreased significantly, but not as much as mean arterial pressure, and were still significantly increased compared with those of control rats. 4. Thus neither mean arterial pressure nor...

...B. Folkow A haemodynamic analysis of resistance vessel behaviour in normo- and hyper-tension has been performed, relating vessel design, degree of contraction, wall distensibility and transmural pressure to each other in a way which allows a semiquantitative prediction of their respective...