... produced by infusion of the corresponding volumes of 5% (w/v) d -glucose alone. 2. The energy expenditure increased and was 33% higher than control ( P <0.001) at 10 μg of dobutamine min −1 kg −1 . The respiratory exchange ratio decreased from 0.85 ( sem 0.02) before infusion to 0.80 ( sem 0.01) at 10...

...) and 70% maximum power (heavy work) on separate days, after an overnight fast. 2. A steady state was achieved in both studies between 20 and 40 min in: oxygen intake (1.42 and 2.64 litres/min respectively); respiratory exchange ratio (0.89 and 1.01); plasma lactate concentration (1.78 and 9.94 mmol/l). 3...

... lactate values in exercise were unchanged by lactate infusion. 3. At rest lactate infusion was associated with an increase in O 2 intake and CO 2 output, the respiratory exchange ratio was unchanged, and plasma HCO − 3 rose by 1·85 mmol/l. 4. During exercise lactate infusion was associated with a smaller...