...Christine Maric-Bilkan Vascular complications are a leading cause of morbidity and mortality in both men and women with type 1 (T1DM) or type 2 (T2DM) diabetes mellitus, however the prevalence, progression and pathophysiology of both microvascular (nephropathy, neuropathy and retinopathy...

...Devy Deliyanti; Jae Young Lee; Steven Petratos; Colin J. Meyer; Keith W. Ward; Jennifer L. Wilkinson-Berka; Judy B. de Haan An imbalance in oxidative stress and antioxidant defense mechanisms contributes to the development of ischaemic retinopathies such as diabetic retinopathy and retinopathy...

... neurovascular unit disorders including stroke and retinopathy. Moreover, the beneficial actions of RAS modulation in brain and retina have been documented in experimental research, but not yet exploited clinically. The RAS is a complex system with distinct yet interconnected components. Understanding...

... and erythrocytes, 5-MTHF (5-methyltetrahydrofolate), and vitamins B12 and B6. Participants were examined ophthalmologically by means of indirect funduscopy and two-field 45 ° fundus photography, and were graded for retinopathy and retinal sclerotic vessel abnormalities. A computer-assisted method was used...

... of VEGF in hypertension-induced vascular injury and its relationship with endothelial function have not been studied. This study included 20 untreated hypertensive men with grade 1 or 2 hypertensive retinopathy, 10 untreated hypertensive men without hypertensive retinopathy and 10 healthy controls. None...

... diabetes with retinopathy. Serum PON1 activity in the group with no complications [median 164.1 nmol·min -1 ·ml -1 (range 8.0–467.8)] was significantly higher than in the group with retinopathy [113.4 nmol·min -1 ·ml -1 (3.0–414.6)] ( P < 0.001), but the serum PON1 concentration was not different...

...-diabetic controls. After correction to 45% packed cell volume, the abnormality had a tendency to be greater in patients with proliferative (mean low shear viscosity, 30·8 mPa s) than background (29·2 mPa s) or nil/minimal retinopathy (27·6 mPa s, 0·05 < P < 0·07, permutational trend test). 2...

...-blockers practolol propranolol retinopathy Clinical Science and Molecular Medicine (1973) 45, 167s-170~. THE EFFECT OF PRACTOLOL ( ERALDIN ) I N THE LONG-TERM TREATMENT OF SEVERE AND MODERATE HYPERTENSION R. M. FULTON, E. H I L D A F U L T O N AND K. G. G R E E N Department of Medicine, Stepping Hill...