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Keywords: rupture
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Articles
Epidermal growth factor receptor inhibitor protects against abdominal aortic aneurysm in a mouse model
Available to PurchaseTakashi Obama, Toshiyuki Tsuji, Tomonori Kobayashi, Yamato Fukuda, Takehiko Takayanagi, Yoshinori Taro, Tatsuo Kawai, Steven J. Forrester, Katherine J. Elliott, Eric Choi, Alan Daugherty, Victor Rizzo, Satoru Eguchi
Journal:
Clinical Science
Clin Sci (Lond) (2015) 128 (9): 559–565.
Published: 11 February 2015
... inhibitor, erlotinib. Without erlotinib, 64.3% of mice were dead due to aortic rupture. All surviving mice had AAA associated with EGFR activation. Erlotinib-treated mice did not die and developed far fewer AAA. The maximum diameters of abdominal aortas were significantly shorter with erlotinib treatment...
Includes: Supplementary data
Articles
Higher levels of collagen and facilitated healing protect against ventricular rupture following myocardial infarction
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (2008) 115 (3): 99–106.
Published: 02 July 2008
...Lu Fang; Xiao-Ming Gao; Chrishan S. Samuel; Yidan Su; Yean Leng Lim; Anthony M. Dart; Xiao-Jun Du The mechanism of cardiac rupture after MI (myocardial infarction) is not fully understood. Rupture has not been reported in most laboratory species, including the rat, but does occur in mice. We have...