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Keywords: salmeterol
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Articles

A tailored approach to asthma management: Arg 16 holds the key?

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Ian Sayers
Journal: Clinical Science
Clin Sci (Lond) (2013) 124 (8): 517–519.
https://doi.org/10.1042/CS20120640
Published: 08 January 2013
... Biochemistry 1994 33 9414 9419 5 Basu K. Palmer C. N. Tavendale R. Lipworth B. J. Mukhopadhyay S. Adrenergic β2-receptor genotype predisposes to exacerbations in steroid-treated asthmatic patients taking frequent albuterol or salmeterol J. Allergy Clin. Immunol. 2009 124...
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Articles

Tailored second-line therapy in asthmatic children with the Arg 16 genotype

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Brian J. Lipworth, Kaninika Basu, Helen P. Donald, Roger Tavendale, Donald F. Macgregor, Simon A. Ogston, Colin N. A. Palmer, Somnath Mukhopadhyay
Journal: Clinical Science
Clin Sci (Lond) (2013) 124 (8): 521–528.
https://doi.org/10.1042/CS20120528
Published: 08 January 2013
...). We therefore evaluated using montelukast as an alternative to salmeterol as tailored second-line asthma controller therapy in children expressing this susceptible genotype. A total of 62 persistent asthmatic children with the homozygous Arg 16 genotype were randomized to receive salmeterol (50 μg...
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