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Keywords: salt-sensitive
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Articles
Sodium bicarbonate loading limits tubular cast formation independent of glomerular injury and proteinuria in Dahl salt-sensitive rats
Available to PurchaseSarah C. Ray, Bansari Patel, Debra L. Irsik, Jingping Sun, Hiram Ocasio, Gene R. Crislip, Chunhua H. Jin, JianKang Chen, Babak Baban, Aaron J. Polichnowski, Paul M. O’Connor
Journal:
Clinical Science
Clin Sci (Lond) (2018) 132 (11): 1179–1197.
Published: 15 June 2018
... the mechanisms mediating this effect remain unclear. The Dahl salt-sensitive (SS) rat develops hypertension and progressive renal injury when fed a high salt diet; however, the effect of alkali loading on kidney injury has never been investigated in this model. We hypothesized that NaHCO 3 protects from...
Articles
Role of the CYP4A/20-HETE pathway in vascular dysfunction of the Dahl salt-sensitive rat
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (2013) 124 (12): 695–700.
Published: 26 February 2013
... dysfunction. There have been a number of reports in human subjects demonstrating an association between elevated urinary excretion of 20-HETE and hypertension, as well as increased 20-HETE production and vascular dysfunction. The Dahl SS (salt-sensitive) rat is a genetic model of salt-sensitive hypertension...
