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Keywords: salt-sensitive hypertension
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Articles
Sheon Mary, Philipp Boder, Giacomo Rossitto, Lesley Graham, Kayley Scott, Arun Flynn, David Kipgen, Delyth Graham, Christian Delles
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (24): 2749–2761.
Published: 17 December 2021
... is still elusive [ 3 ]. blood pressure renal physiology Salt salt-sensitive hypertension Tamm Horsfall protein Correspondence: Christian Delles ( [email protected] ) * These authors contributed equally to this work. 21 10 2021 24 11 2021 06 12 2021...
Includes: Supplementary data
Articles
No evidence for brain renin–angiotensin system activation during DOCA-salt hypertension
Available to PurchaseEstrellita Uijl, Liwei Ren, Katrina M. Mirabito Colafella, Richard van Veghel, Ingrid M. Garrelds, Oliver Domenig, Marko Poglitsch, Ivan Zlatev, Jae B. Kim, Stephen Huang, Lauren Melton, Ewout J. Hoorn, Don Foster, A.H. Jan Danser
Journal:
Clinical Science
Clin Sci (Lond) (2021) 135 (2): 259–274.
Published: 22 January 2021
... Limited on behalf of the Biochemical Society 2021 angiotensin II angiotensinogen brain mineralocorticoid receptor antagonism RNAi therapeutics salt-sensitive hypertension Parametric data are expressed as mean values ± SEM and were analyzed using a one-way analysis of variance (ANOVA...
Includes: Supplementary data
Articles
Relationship between the renin–angiotensin–aldosterone system and renal K ir 5.1 channels
Available to PurchaseAnna D. Manis, Oleg Palygin, Sherif Khedr, Vladislav Levchenko, Matthew R. Hodges, Alexander Staruschenko
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (24): 2449–2461.
Published: 18 December 2019
... in salt-sensitive hypertension. However, mechanisms pertaining to the impact of K ir 4.1/K ir 5.1-mediated K + transport on the renin–angiotensin–aldosterone system (RAAS) remain unclear. Herein, we utilized a knockout of Kcnj16 in the Dahl salt-sensitive rat (SS Kcnj16-/- ) to investigate...
Includes: Supplementary data
Articles
Introgression of Brown Norway CYP4A genes on to the Dahl salt-sensitive background restores vascular function in SS-5 BN consomic rats
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (2013) 124 (5): 333–342.
Published: 16 November 2012
... (CYP4A) oxidative stress salt-sensitive hypertension vascular dysfunction • Recent studies have reported an association between increased urinary 20-HETE excretion, endothelial dysfunction and elevated blood pressure in humans. • The present study used Dahl SS (salt-sensitive) rats...
Articles
Riboflavin Analogues: A Novel Class of Antihypertensive Drugs
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (s8): 129s–132s.
Published: 01 October 1982
... as dual-mechanism diuretic agents with K + sparing properties and thus act as a novel class of antihypertensive drugs. © 1982 The Biochemical Society and the Medical Research Society 1982 aldosterone hydrochlorothiazide potassium riboflavin analogues salt-sensitive hypertension sodium balance...